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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:03 AM EDT

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Showing 1–24 of 666 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: TDCS (Transcranial Direct-current Stimulation) Clear all
Completed No phase listed Observational Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) and Cognitive Processing

NCT01602263
View directory record Official record
Conditions
Aphasia, Autism, Schizophrenia
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 79 Years
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 19, 2026, 8:03 AM EDT
Active, not recruiting Not applicable Interventional

Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health

NCT07812987
View directory record Official record
Conditions
Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions
AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation
Behavioral · Device
Lead sponsor
Tactical Mind Research Coalition, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD)

NCT05478681
View directory record Official record
Conditions
Alzheimer Disease
Interventions
active tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
60 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944
View directory record Official record
Conditions
Depression, Anxiety and Fear
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Evaluating tDCS Brain-stimulation in Depression Using MRI

NCT05598034
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Left DLPFC tDCS, Right DLPFC tDCS, Cognitive task
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Not listed Not applicable Interventional

Priming With tDCS: Expanding the Window of Recovery in Chronic Stroke

NCT03964467
View directory record Official record
Conditions
Upper Extremity Paresis
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of the Sciences in Philadelphia
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2023 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) for Post COVID-19 Fatigue

NCT04876417
View directory record Official record
Conditions
Post Covid-19 Patients
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 19, 2026, 8:03 AM EDT
Not listed Not applicable Interventional

The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain

NCT05571215
View directory record Official record
Conditions
Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
Interventions
Transcranial Direct Current Stimulation, Pain Neuroscience Education
Device · Behavioral
Lead sponsor
High Point University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Regulating Homeostatic Plasticity and the Physiological Response to rTMS

NCT03309696
View directory record Official record
Conditions
Tinnitus
Interventions
sham tDCS and sham rTMS, sham tDCS and active rTMS, active tDCS and active rTMS
Device
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits

NCT06771531
View directory record Official record
Conditions
Somatosensory Function, Balance Control, Mobility
Interventions
transcranial direct current stimulation, active sham stimulation
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Optimization of NIBS for Treatment of Addiction

NCT04379115
View directory record Official record
Conditions
Opioid-use Disorder, Chronic Pain
Interventions
Active Comparator: Active tDCS + Active TUS, Sham Comparator: Sham tDCS + Sham TUS
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 85 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Hinsdale, Illinois • Cambridge, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

NCT04897334
View directory record Official record
Conditions
Ischemic Stroke, Cognitive Impairment
Interventions
tDCS, sham tDCS, Cognitive Therapy
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury

NCT03302793
View directory record Official record
Conditions
Pain Management
Interventions
BreEStim, tDCS, tDCS sham
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 19, 2026, 8:03 AM EDT
Not yet recruiting Not applicable Interventional

Lily's Grace Temporal Interference

NCT07520955
View directory record Official record
Conditions
Epilepsy
Interventions
TES-TI, Sham Stimulation, Structural and Functional MRI
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Active, not recruiting Not applicable Interventional

Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

NCT04675398
View directory record Official record
Conditions
Parkinson Disease
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated Phase 1 Interventional

Adaptive tDCS for Treatment-Resistant MDD

NCT02942368
View directory record Official record
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
tDCS
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TDCS to Improve Motivation and Memory in Elderly (TIME)

NCT04268186
View directory record Official record
Conditions
Motivation
Interventions
Direct tDCS, Indirect tDCS, Personalized tDCS, Sham tDCS
Device
Lead sponsor
Northeastern University
Other
Eligibility
65 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Phase 1Phase 2 Interventional

Effects of Direct Transcranial Current Stimulation on Central Neural Pain Processing in Fibromyalgia

NCT01745003
View directory record Official record
Conditions
Fibromyalgia
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional

NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery

NCT02020421
View directory record Official record
Conditions
Aphasia
Interventions
rTMS, tDCS, Sham rTMS, Sham tDCS
Device
Lead sponsor
Dr. Alexander Thiel
Individual
Eligibility
50 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep

NCT04461769
View directory record Official record
Conditions
Sleep, Sleep Hygiene
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
Brain Electrophysiology Laboratory Company
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Home-based Transcranial Direct Current Stimulation for Pain Management in Persons With Alzheimer's Disease and Related Dementias

NCT04457973
View directory record Official record
Conditions
Alzheimer's Disease and Related Dementias
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Improving SCI Rehabilitation Interventions by Retraining the Brain

NCT03892746
View directory record Official record
Conditions
Cervical Spinal Cord Injruy
Interventions
Active tDCS + task oriented practice, Sham tDCS + task oriented practice
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
4
States / cities
West Orange, New Jersey • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 19, 2026, 8:03 AM EDT
Not yet recruiting Not applicable Interventional

Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments

NCT07599774
View directory record Official record
Conditions
Hemiparetic Stroke
Interventions
High-definition transcranial direct stimulation: sham, High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy
Device · Behavioral
Lead sponsor
Carle Foundation Hospital
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated Not applicable Interventional

Modulating Neuropathic Pain With Transcranial Direct Current Stimulation

NCT04581525
View directory record Official record
Conditions
Pain, Neuropathic, Complex Regional Pain Syndromes, Phantom Limb Pain, Spinal Cord Injuries
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Susan McDowell
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 19, 2026, 8:03 AM EDT