- Conditions
- Total Knee Arthroplasty
- Interventions
- IO Administration of Cefazolin, IO Administration of Vancomycin, IV Administration of Cefazolin, IV Administration of Vancomycin
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2035
- U.S. locations
- 1
- States / cities
- Houston, Texas
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 49–72
of 290
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Wear of Articular Bearing Surface of Prosthetic Joint, Total Knee Arthroplasty
- Interventions
- Polyethylene
- Device
- Lead sponsor
- Osaka Metropolitan University
- Other
- Eligibility
- 20 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Knee Osteoarthritis, Pain Management
- Interventions
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 167 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 6
- States / cities
- Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 3 more
- Conditions
- Knee Arthroplasty
- Interventions
- Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System
- Procedure · Device
- Lead sponsor
- Northwest Surgical Specialists, Vancouver
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2023
- U.S. locations
- 1
- States / cities
- Vancouver, Washington
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methadone
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Denver, Colorado
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total Knee Arthroplasty
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 299 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2033
- U.S. locations
- 12
- States / cities
- Atlanta, Georgia • Boston, Massachusetts • Novi, Michigan + 8 more
- Conditions
- Knee Osteoarthritis, Arthroplasty Complications, Postoperative Pain
- Interventions
- Dexamethasone, Acetaminophen, Lyrica, Celebrex, Meloxicam, Oxycodone, Ropivacaine
- Drug
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Comprehensive Behavioral Intervention, Standard of Care Exercise Program
- Behavioral · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Knee
- Interventions
- Journey II Bi-Cruciate Stabilized TKA, Journey II Cruciate Retaining TKA, Journey II Bi-Cruciate Retaining TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Total Knee Replacement Surgery, Total Hip Replacement Surgery
- Interventions
- XPERIENCE Advanced Surgical Irrigation, Standard of Care Irrigation
- Device · Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Arthritis Knee
- Interventions
- Robotic assisted total knee arthroplasty, Manual total knee arthroplasty, Robotic assisted revision total knee arthroplasty, Manual revision total knee arthroplasty
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 30 participants
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Moderate Varus, Valgus or Flexion Deformities, Avascular Necrosis of the Femoral Condyle
- Interventions
- Zimmer Persona Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 737 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2027
- U.S. locations
- 14
- States / cities
- Denver, Colorado • Fort Collins, Colorado • Parker, Colorado + 11 more
- Conditions
- Osteo Arthritis Knee
- Interventions
- Unicompartmental knee arthroplasty, Total knee arthroplasty
- Procedure
- Lead sponsor
- Anderson Orthopaedic Research Institute
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Alexandria, Virginia
- Conditions
- Osteoarthritis, Knee
- Interventions
- Moving Well, Staying Well
- Behavioral
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Injuries, Knee Imlant
- Interventions
- MicroPort Medial Pivot TKA, DePuy Attune PCR TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 3
- States / cities
- Las Vegas, Nevada • Knoxville, Tennessee
- Conditions
- Total Knee Arthroplasty
- Interventions
- Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design, Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- TKA, THA, Anxiety, Binaural Beats, Music Exposure, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Total Knee Replacement, Total Hip Replacement
- Interventions
- Binaural Beats Audio Intervention, Music of Choice
- Other
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee, Arthrofibrosis
- Interventions
- Tryptase, Serum test
- Diagnostic Test
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 20 Years to 100 Years
- Enrollment
- 219 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
- Interventions
- SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
- Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Redwood City, California
- Conditions
- Anemia, Arthritis, Total Knee Arthroplasty, Total Hip Arthroplasty
- Interventions
- Conventional Oral TXA (Tranexamic Acid), Multi-Dose Oral TXA (Tranexamic Acid)
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Knee Osteoarthritis, Knee Arthropathy
- Interventions
- Mechanical Alignment (MA), Kinematic Alignment (KA) Interventions:
- Procedure
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 21 Years to 79 Years
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Prosthetic-joint Infection
- Interventions
- PLG0206, Placebo
- Drug
- Lead sponsor
- Peptilogics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 15
- States / cities
- Sarasota, Florida • Tamarac, Florida • Shreveport, Louisiana + 12 more
- Conditions
- Knee Replacement, Total Knee Arthroplasty, Post-Operative Pain
- Interventions
- Liposomal bupivacaine, Bupivacaine
- Drug
- Lead sponsor
- Northern Light Mercy Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Portland, Maine
- Conditions
- Unilateral Knee Arthroplasty
- Interventions
- Preop acetaminophen IV, Preop orphenadrine IV, Postop oral oxycodone & acetaminophen, Postop hydromorphone IV, Postop oral orphenadrine, Postop oral oxycodone, Postop acetaminophen IV, Postop orphenadrine IV
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Winter Park, Florida