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Conditions: Bone Metastases
Interventions: Bone Scan: F18-Fluoride PET/CT or TC-MDP; Device
Lead sponsor: American College of Radiology - Image Metrix; Industry
Eligibility: 18 Years and older
Enrollment: 550 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 15
States / cities: Scottsdale, Arizona • Freemont, California • Los Angeles, California + 9 more

Conditions: Cigarette Smoking
Interventions: E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling, Ecological Momentary Intervention (EMI) Text Messaging; Other · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Use Disorder
Interventions: CM-PST, CM only; Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 18 Years to 24 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Psychosis, Psychosis Nos/Other, Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Prodromal Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizophreniform Disorders, Major Depression With Psychotic Features, Unspecified Psychosis, Bipolar Disorder
Interventions: Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care; Device · Behavioral · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 15 Years to 40 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Congestive Heart Failure
Interventions: Drug therapy for HF, NT-proBNP guided HF therapy; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 21 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid Use
Interventions: Life Care Specialist (LCS) Intervention, Clinical Coordination with Referrals, Pilot Study of Pain Management Strategies; Behavioral · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 333 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tobacco Dependence
Interventions: Standard, Deep Cultural; Behavioral
Lead sponsor: University of Massachusetts, Boston; Other
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV, Opioid Abuse
Interventions: Standard Care, Text Messaging CBT (TXT-CBT); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
Interventions: Usual Care, Pain Self-Management; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 17
States / cities: Baltimore, Maryland • Allison Park, Pennsylvania • Blawnox, Pennsylvania + 9 more

Conditions: Tobacco Cessation
Interventions: Tailored behavioral counseling, Tobacco cessation pharmacotherapy; Behavioral · Drug
Lead sponsor: Iowa City Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: HIV/AIDS
Interventions: Seek and Test Phase, Treat and Retain Phase; Behavioral
Lead sponsor: New York University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Device-Related Thrombosis, Atrial Fibrillation, Left Atrial Appendage Occlusion
Interventions: ASA plus Clopidogrel, Genetic-Tailored AntiThrombotic Strategy, Half-Dose of novel OAC; Drug
Lead sponsor: Texas Cardiac Arrhythmia Research Foundation; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Dental Fear
Interventions: A stepped-care approach to the treatment of dental fear; Dental Fearless; Behavioral
Lead sponsor: New York University; Other
Eligibility: 13 Years to 99 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Head and Neck Cancer
Interventions: Tailored Nutrition Intervention, Nutrition plus Exercise; Other · Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Musculoskeletal Pain, Chronic Pain, Osteoarthritis, Pain, Chronic, Movement Evoked Pain
Interventions: PROACTIVE Intervention; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 92 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
Interventions: CBPT-ACLR, Education; Behavioral · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 14 Years to 35 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Garfield Heights, Ohio • Nashville, Tennessee

Conditions: Overweight, Obesity, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions: Simplified Dietary Self-Monitoring, Detailed Dietary Self-Monitoring, Core Behavioral Weight Loss Intervention; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 328 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Obesity, Metabolic Disease
Interventions: Standard Care, Culturally-tailored dietary and behavioral intensive lifestyle intervention, Placebo, Tirzepatide; Behavioral · Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 21 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Parent-Child Relations, Parenting Self Efficacy, Child Mental Health
Interventions: Project Support, Case Management Services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 6 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Suicide and Depression, Adolescent Behavior
Interventions: iCHART, Treatment As Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 18 Years
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 13
States / cities: Gibbsboro, New Jersey • Johnstown, Pennsylvania • Philadelphia, Pennsylvania + 4 more

Conditions: COVID-19 Testing Behaviors
Interventions: COVID-19 rapid test-to-treat, Standard COVID19 education control arm; Behavioral
Lead sponsor: University of Missouri, Kansas City; Other
Eligibility: 18 Years to 120 Years
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Suicide, Psychosis
Interventions: Cognitive Behavioral Suicide Prevention for psychosis CBSPp); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Type 2 Diabetes
Interventions: Decision support, Facilitated referral to a cardiometabolic team-based center; Other
Lead sponsor: American College of Cardiology; Other
Eligibility: 18 Years and older
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

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F18PET/CT Versus TC-MDP Scanning to Detect Bone Mets

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

StuDy AimED at Increasing AlCohol AbsTinEnce

EPI-MINN: Targeting Cognition and Motivation - National

Use of NT-proBNP Testing to Guide Heart Failure Therapy in the Outpatient Setting.

Life Care Specialists (LCS) With a Focus on Patient Pain Management and Prevention of Substance Misuse

Tobacco Dependence Treatment for Asian Americans

Cell Phone Technology Targeting ART Adherence and Drug Use

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

Hybrid STTR Intervention for Heterosexuals: Anonymous Testing and Confidential Care Linkage

Efficacy of Different Anti-Thrombotic Strategies on Device-Related Thrombosis Prevention After Percutaneous Left Atrial Appendage Occlusion

A Stepped Care Approach to Treating Dental Fear

Nutrition and Resistance Training in Head and Neck Cancer

The PROACTIVE Study for Black Elders

Improving ACL Reconstruction Outcomes: CBPT

Simplifying Diet Tracking in a Digital Weight Loss Intervention

Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity

Examining Whether Project Support Works

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

COVID-19 Rapid Test-to-Treat With African American Churches (Faithful Response II)

Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1

Transform CV Risk in Diabetes