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ClinicalTrials.gov public records Last synced Oct 15, 2026, 10:49 AM EDT

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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
Conditions
Epilepsy
Interventions
temporally-interfering electric field stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
2
States / cities
Sacramento, California • Atlanta, Georgia
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Brain Stimulation

NCT03747601
Conditions
Visual Acuity
Interventions
Temporal Interference (TI) Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Healthy Volunteers
Interventions
Transcranial electrical stimulation with Temporal Interference (TES-TI)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Anxiety, PTSD
Interventions
Electrical stimulation device
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Healthy Participants
Interventions
Temporal Interference Transcranial electrical stimulation (TI-TES), Sham stimulation
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Not yet recruiting Not applicable Interventional

Lily's Grace Temporal Interference

NCT07520955
Conditions
Epilepsy
Interventions
TES-TI, Sham Stimulation, Structural and Functional MRI
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Schizophrenia
Interventions
TES-TI, Sham TES-TI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Interpersonal Expectations on Negative Affect

NCT06980090
Conditions
Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
Interventions
Session A: Positive Placebo + Active tTIS, Session B: Positive Placebo + Sham tTIS, Session C: Negative Placebo + Active tTIS, Session D: Negative Placebo + Sham tTIS, Session E: On-Placebo + Sham tTIS, Session F: Off-Placebo + Sham tTIS
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hanover, New Hampshire
Conditions
Epilepsy
Interventions
Temporal Interference Electrical Stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Conditions
Healthy Adult Participants, Healthy Participants
Interventions
Magnetic Resonance Imaging (MRI), Broad thalamic stimulation (TI-TES), Carrier only SHAM stimulation, Anterior thalamic stimulation (TI-TES), Posterior thalamic stimulation (TI-TES)
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Left and Right Hemisphere Contributions to Speech Perception

NCT04989309
Conditions
Neural Bases of Speech Perception
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.2

NCT07339072
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

The STRENGTHEN Study

NCT06267521
Conditions
Cognitive Flexibility, Emotional Regulation
Interventions
Healthy Minds Program, Sham Meditation Didactic Material, Sham Stimulation in Lab, Stimulation in Lab, MRI Scanner
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Power Nap With TES-TI

NCT07090135
Conditions
Non-restorative Sleep, Healthy Volunteer
Interventions
Transcranial electrical stimulation with Temporal Interference (TES-TI)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Not yet recruiting Not applicable Interventional

Overnight TI in TLE

NCT07434986
Conditions
Temporal Lobe Epilepsy (TLE), Drug Resistant Epilepsy, Sleep
Interventions
Non-invasive Temporal Interference (TI) Stimulation Targeting Bilateral Hippocampi
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 2

NCT06601699
Conditions
Healthy
Interventions
Transcranial electrical stimulation (TES), Transcranial electrical stimulation with temporal interference (TES-TI)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation and Decision-making

NCT04099056
Conditions
Depression
Interventions
Neurostimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 50 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Healthy Adult Participants
Interventions
transcranial Temporal Interference Stimulation
Device
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.3

NCT07594795
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Active, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Addiction Treatment

NCT07210268
Conditions
Nicotine Use Disorder, Substance Use Disorders
Interventions
TI-NDBS, Sham TI-NDBS
Device
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bloomington, Indiana • Indianapolis, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

NCT06601686
Conditions
Healthy
Interventions
Transcranial electrical stimulation (TES), Transcranial electrical stimulation with temporal interference (TES-TI), Sham stimulation
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Drug-Resistant Focal Epilepsy
Interventions
Temporal Interference Stimulation, Direct Electrical Stimulation
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.1

NCT07215299
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - NAcc TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc TI Sham, Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Active, Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Stimulation for Social Cognition

NCT06607432
Conditions
Healthy Controls
Interventions
Transcranial Interference Stimulation (tIS), Sham tIS
Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York