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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Tenaculum Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion

NCT02391714
View directory record Official record
Conditions
Contraception
Interventions
IUD insertion, Povidone-Iodine, Chlorhexidine, Oxygen, Nitrous oxide
Procedure · Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
12 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Lidocaine for Intrauterine Device Insertion Pain

NCT01411995
View directory record Official record
Conditions
Pain
Interventions
2% lidocaine gel, Water based lubricant
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Allis Clamp Versus Single-tooth Tenaculum

NCT05187078
View directory record Official record
Conditions
IUD
Interventions
Allis clamp, Single-tooth tenaculum
Procedure
Lead sponsor
Brooke Andrews
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 6, 2026, 2:13 AM EDT
Terminated Not applicable Interventional

Detection of Tumor Associated Cell-free DNA in Peritoneal Fluid Obtained by Culdocentesis

NCT02441140
View directory record Official record
Conditions
Stage III Ovarian Cancer, Stage IV Ovarian Cancer
Interventions
Culdocentesis, Vaginal Swab, Chromopertubation, Blood collection, Tissue collection
Procedure
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Sep 6, 2026, 2:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Menstrual Phase Endometrial Scratch in IUI Cycles

NCT04641598
View directory record Official record
Conditions
Fertility Disorders, Fertility Issues
Interventions
Endometrial Scratch, Sham procedure
Procedure
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 37 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Versus Intracervical Lidocaine

NCT00816751
View directory record Official record
Conditions
Abortion, Induced, Pain
Interventions
Paracervical block, Intracervical, Buffered Lidocaine, vasopressin, sodium bicarbonate
Procedure · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Phase 2 Interventional

Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement

NCT07487246
View directory record Official record
Conditions
Pain Management, Abortion, Second Trimester Abortion, Dilation and Evacuation
Interventions
Ketorolac, oral ibuprofen, Placebo, Lidocaine HCl 1%, Saline
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation

NCT02852434
View directory record Official record
Conditions
Pain Management, Cervical Preparation
Interventions
Lidocaine Gel (2%), Lidocaine Paracervical Block (1%)
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Topical Lidocaine for Pain Control With Intrauterine Device (IUD) Insertion

NCT01445756
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 25, 2014 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

RCT of Pain Perception With Fast and Slow Tenaculum Application

NCT05458037
View directory record Official record
Conditions
Pain, Acute, Pain, Procedural
Interventions
Speed of tenaculum application
Procedure
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intracervical Lidocaine Gel for IUD Insertional Pain

NCT01214161
View directory record Official record
Conditions
Pain
Interventions
2% lidocaine gel, placebo
Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Refining Paracervical Block Techniques for Pain Control in First Trimester Surgical Abortion

NCT01466491
View directory record Official record
Conditions
Pain
Interventions
Paracervical block technique with lidocaine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Sep 6, 2026, 2:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Novel Cervical Retraction Device

NCT02283463
View directory record Official record
Conditions
Pain Due to Certain Specified Procedures
Interventions
Intrauterine device (IUD) insertion, Endometrial biopsy
Device · Procedure
Lead sponsor
Bioceptive
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

Assessing Pain and Effectiveness of Carevix Device for IUD Insertions

NCT07290517
View directory record Official record
Conditions
IUD, Abnormal Uterine Bleeding, Pain, Cervical
Interventions
Carevix, Tenaculum
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

NCT06960317
View directory record Official record
Conditions
Contraception, Pain, Acute, Anesthesia, Local
Interventions
Buffered Lidocaine, Sham Comparator, Unbuffered lidocaine, Xylocaine jelly 2%, Surgilube
Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Two Instruments for Stabilization of the Cervix During Office Procedures

NCT01769131
View directory record Official record
Conditions
Comparing Two Clamps for Mobilization of the Cervix During Common Gynecologic Office Procedures
Interventions
Not listed
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 6, 2026, 2:13 AM EDT
Not yet recruiting Phase 2 Interventional

Investigating Pre-Procedural Anxiety and Effect of Analgesia on Intrauterine Device Placement and Endometrial Biopsy

NCT07031206
View directory record Official record
Conditions
Anxiety, Pain
Interventions
Paracervical block- Lidocaine without epinephrine, Benzocaine Gel applied to the cervix, Hydroxyzine Hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Block for Pain Control With Osmotic Dilator Placement

NCT02354092
View directory record Official record
Conditions
Abortion Late, Pain
Interventions
Local anesthetic for tenaculum placement, Sham, Paracervical Block, Dilator Placement, Post-procedural assessment, Preprocedural pain control
Procedure · Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tenaculum Pain Control Study

NCT01421641
View directory record Official record
Conditions
Cervical Pain, Pelvic Pain
Interventions
Intracervical Lidocaine Injection, Topical Lidocaine Gel
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

12 Versus 20 mL PCB for D&E Cervical Prep

NCT03356145
View directory record Official record
Conditions
Pain
Interventions
12 mL paracervical block, 20 mL paracervical block
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Suction Cervical Stabilizer Compared to Standard Tenaculum for Intrauterine Procedures

NCT06193590
View directory record Official record
Conditions
Intrauterine Device (IUD), Abnormal Uterine Bleeding
Interventions
Carevix, Tenaculum
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Pain Control With Hormonal IUS Insertion

NCT02352714
View directory record Official record
Conditions
Pain
Interventions
Paracervical Nerve Block, Sham Paracervical Block
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 22 Years · Female only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

NCT06141447
View directory record Official record
Conditions
Hemorrhage
Interventions
Oxytocin + normal saline, Normal saline
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pain Control for Intrauterine Device Placement Using Paracervical Block

NCT02219308
View directory record Official record
Conditions
Pain Due to Intrauterine Contraceptive Device
Interventions
Paracervical Block (PCB), No Paracervical Block (Sham PCB)
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 6, 2026, 2:13 AM EDT