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ClinicalTrials.gov public records Last synced Oct 18, 2026, 11:59 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 208 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Test Lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)

NCT06698731
View directory record Official record
Conditions
Presbyopia Condition
Interventions
Test lens, Control lens
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
45 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

NCT05427539
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.

NCT03951610
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Anaheim, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens

NCT01412983
View directory record Official record
Conditions
Myopia
Interventions
Bausch & Lomb Test lens, Ciba Vision soft contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2014 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

A 6-Hour Clinical Evaluation of New Daily-Wear Soft Contact Lenses

NCT03235089
View directory record Official record
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional

A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add

NCT06869044
View directory record Official record
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Manufacturing Processes for a Reusable Multifocal Optical Design in a Presbyopic Population

NCT03787472
View directory record Official record
Conditions
Visual Acuity
Interventions
JJV Investigational senofilcon A Multifocal Lens1, JJV Investigational senofilcon A Multifocal Lens2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
5
States / cities
Maitland, Florida • Raytown, Missouri • Jamestown, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Oct 18, 2026, 11:59 AM EDT
Recruiting Not applicable Interventional

Ultrasound Neuromodulation in Essential Tremor

NCT06610877
View directory record Official record
Conditions
Essential Tremor, Neuromodulation
Interventions
Focused Ultrasound Neuromodulation - Sham Control, Focused ultrasound neuromodulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear

NCT06161012
View directory record Official record
Conditions
Ocular Physiology
Interventions
Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Granville, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05291936
View directory record Official record
Conditions
Ocular Physiology
Interventions
PRECISION1® for Astigmatism Contact Lenses, MyDay® Toric Soft Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle

NCT01234207
View directory record Official record
Conditions
Presbyopia
Interventions
Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
39 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye

NCT03417505
View directory record Official record
Conditions
Dry Eye, Dry Eye Syndromes
Interventions
Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
Device
Lead sponsor
Tangible Science
Industry
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Sacramento, California • Fort Lauderdale, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 18, 2026, 11:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
View directory record Official record
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Investigational Daily Disposable Multifocal Contact Lenses Produced With Different Manufacturing Processes in Myopes

NCT04889625
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A C3, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
Jacksonville, Florida • Saint Augustine, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear

NCT04050618
View directory record Official record
Conditions
Myopia
Interventions
fanfilcon A test lens, ocufilcon D control lens, etafilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
6
States / cities
Whittier, California • Longwood, Florida • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Reusable Soft Contact Lenses

NCT06119191
View directory record Official record
Conditions
Myopia
Interventions
Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Berkeley, California • Bloomington, Indiana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 18, 2026, 11:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Performance Assessment Study VitalSigns Camera

NCT05465018
View directory record Official record
Conditions
Healthy Humans, Vital Signs Monitoring
Interventions
Happy Flow / Baseline, Make-up, Sunglasses, Face mask, Minimum requirements camera, Worst case hardware, Damaged lens, Face or chest outside test frame
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop

NCT06131476
View directory record Official record
Conditions
Visual Acuity
Interventions
Blink® Tears eye drops, Investigational lipid eye drops
Drug
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Jacksonville, Florida • Saint Augustine, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.

NCT05361304
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A contact lenses made with a novel manufacturing technology, senofilcon A contact lenses made with the current manufacturing technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT04974697
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
8
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 18, 2026, 11:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study

NCT05582304
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 18, 2026, 11:59 AM EDT