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Showing 1–24 of 132 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Myopia
Interventions
stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Athens, Ohio + 1 more
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Conditions
Myopia, Contact Lenses
Interventions
Bausch & Lomb new daily disposable, Johnson & Johnson Acuvue Moist
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Ocular Imaging in Neurodegeneration

NCT03699644
Conditions
Alzheimer Disease, Alzheimer Dementia, Frontotemporal Dementia
Interventions
Spectral-Domain Optical Coherence Tomography (SD-OCT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Comprehensive Ophthalmic Examination, Fundus Photography
Device · Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study

NCT05582304
Conditions
Visual Acuity
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Athens, Georgia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers

NCT06333613
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
13 Years to 39 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
5
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYPRESS Efficacy and Safety Study Extension

NCT04947735
Conditions
Juvenile Myopia, Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
11
States / cities
Whittier, California • Longwood, Florida • Pittsburg, Kansas + 8 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Visual Mode Switching in Color Perception

NCT05779228
Conditions
Perception of Things Changing Color, Adaptive Behavior
Interventions
Mode Switching Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line

NCT04794270
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
5
States / cities
Longwood, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Conditions
Myopia
Interventions
Bausch & Lomb Test lens, Ciba Vision soft contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Conditions
Ocular Comfort
Interventions
Lotrafilcon A test contact lens, Lotrafilcon A control contact lens, Ultra-High Resolution Optical Coherence Tomographer (OCT)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Results available

Dispensing Study for a New Study Lens

NCT02642991
Conditions
Myopia
Interventions
Phenacite, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Completed No phase listed Interventional Accepts healthy volunteers Results available

Visual Performance of Soft Contact Lenses With Myopia Control Optics

NCT05141448
Conditions
Visual Acuity
Interventions
1-Day Acuvue Moist, EMO-118, EMO-114, MiSight® 1 day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Myopia
Interventions
Sapphire Lens, enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Completed Not applicable Interventional Results available

1 Week Crossover Study Between Two Soft Contact Lenses

NCT06611410
Conditions
Myopia
Interventions
Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects

NCT05509608
Conditions
Electrode Site Reaction
Interventions
RM Electrode, ERG Jet Electrode
Device
Lead sponsor
RetMap, Inc
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois