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Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Test Lens 2 Clear all
Completed Not applicable Interventional Results available

Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types

NCT06232590
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design

NCT04952701
View directory record Official record
Conditions
Presbyopia
Interventions
Control lenses, Test lenses
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional

A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add

NCT06869044
View directory record Official record
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers

NCT06333613
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
13 Years to 39 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
5
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 3, 2026, 10:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYPRESS Efficacy and Safety Study Extension

NCT04947735
View directory record Official record
Conditions
Juvenile Myopia, Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
11
States / cities
Whittier, California • Longwood, Florida • Pittsburg, Kansas + 8 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line

NCT04794270
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
5
States / cities
Longwood, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression

NCT01423773
View directory record Official record
Conditions
Ocular Comfort
Interventions
Lotrafilcon A test contact lens, Lotrafilcon A control contact lens, Ultra-High Resolution Optical Coherence Tomographer (OCT)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2022 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

A Bilateral Dispensing Clinical Trial of an Sapphire Lens Against Senofilcon A Toric for Astigmatism Lens

NCT02555098
View directory record Official record
Conditions
Astigmatism
Interventions
Sapphire contact lenses, senofilcon A contact lenses
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Campbell, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 3, 2026, 10:07 AM EDT
Completed No phase listed Interventional Results available

Clinical Validation of the Apollo Daily Disposable Soft Contact Lenses

NCT05035017
View directory record Official record
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

1 Week Crossover Study Between Two Soft Contact Lenses

NCT06611410
View directory record Official record
Conditions
Myopia
Interventions
Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 3, 2026, 10:07 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects

NCT05509608
View directory record Official record
Conditions
Electrode Site Reaction
Interventions
RM Electrode, ERG Jet Electrode
Device
Lead sponsor
RetMap, Inc
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Evaluating Two Multifocal Daily Disposable Contact Lenses

NCT05579886
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens, Test Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of a Contact Lens for Daily Disposable Use

NCT01365039
View directory record Official record
Conditions
Myopia
Interventions
Test, daily disposable contact lens, SofLens daily disposable contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 40 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Two Marketed Multifocal Contact Lenses

NCT03322423
View directory record Official record
Conditions
Visual Performance
Interventions
Multifocal Contact Lens 1, Multifocal Contact Lens 2, Spherical Contact Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Sarasota, Florida • Albuquerque, New Mexico • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers

NCT03222037
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A, Control
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions

NCT01791517
View directory record Official record
Conditions
Contact Lens Solutions
Interventions
Solution 1 (Test), Solution 2 (Test), Solution 3 (Test), Solution 4 (Control)
Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population

NCT03581825
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal, etafilcon A Sphere
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Orlando, Florida • East Lansing, Michigan • Raytown, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Spectacles for Patients With Down Syndrome

NCT03367793
View directory record Official record
Conditions
Vision, Low
Interventions
Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2021 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Visual Performance of Two Types of Cosmetic Contact Lenses

NCT04534764
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A with cosmetic pattern, 1-Day Acuvue DEFINE Vivid Style
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Maitland, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 3, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Multifocal Contact Lens Designs With and Without an HEV Blocker on Visual Function

NCT04995055
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens TEST Lens, ACUVUE® OASYS Multifocal
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Sep 3, 2026, 10:07 AM EDT