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Showing 1–24 of 108 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Text message smoking treatment Clear all
Recruiting Phase 4 Interventional

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

NCT06598397
View directory record Official record
Conditions
Human Immunodeficiency Virus (HIV), Smoking Cessation
Interventions
Motivational Interviewing (MI) Counseling, Peer Mentoring, Skills-based Text Messaging, Combination NRT
Behavioral · Drug
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

NCT06053567
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Aerobic Exercise, Counseling, Nicotine patch
Behavioral · Drug
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Results available

iQuit Mindfully: Text Messaging for Smoking Cessation

NCT03029819
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Mindfulness-based Addiction Treatment, iQuit Mindfully, Self-Help guide, Nicotine Patch
Behavioral · Drug
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional

Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients

NCT05021185
View directory record Official record
Conditions
Tobacco Dependence, Tobacco Use Cessation, Cancer
Interventions
Interactive Mobile Doctor (iMD)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

NCT07447635
View directory record Official record
Conditions
Smoking Cessation, Alcohol Use
Interventions
Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA), Quitline Support
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults

NCT05847673
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Take A Break - Rural

NCT05790486
View directory record Official record
Conditions
Smoking, Smoking Behaviors, Smoking Cessation
Interventions
Take a Break plus Nicotine replacement therapy (NRT) Sampling, The Comparison, Community Paramedicine Standard Plus Enhanced Implementation Program, Community Paramedicine Standard Implementation Program
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

mHealth Mood Management Tool (Actify) to Improve Population-Level Smoking Cessation

NCT04525222
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Health Promotion and Education, Smoking Cessation Intervention (Actify app), Smoking Cessation Intervention (Current Standard Care app), Survey Administration
Other · Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Messaging for Smoking Cessation in College Health Clinics

NCT02191033
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking counseling, Text messaging, Nicotine patch
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 4 Interventional Results available

Engagement With an Adaptive Mobile Health Smoking Cessation Intervention

NCT04020718
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Brief telephone advice plus tailored text messages, Mailed nicotine replacement therapy, Proactive telephone coaching
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Sep 1, 2026, 11:45 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Adaptive Treatment Strategies for Improving Engagement With a Web-Based Smoking Intervention in Socially Anxious Smokers

NCT04260776
View directory record Official record
Conditions
Social Anxiety Disorder, Tobacco Use Disorder
Interventions
Phase 1: Web-based intervention (MyWebQuit) with 1-way text messages, Phase 1: Web-based intervention (MyWebQuit) with interactive, 2-way text messages, Phase 2: re-engagement text messages, Phase 2: re-engagement emails
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco

NCT04737772
View directory record Official record
Conditions
Smoking Cessation, Marijuana Use
Interventions
Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
21 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Not applicable Interventional

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

NCT06582693
View directory record Official record
Conditions
Smoking, Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Refer2Quit
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
3,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

NCT06644664
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Quitline Support Study

NCT03538938
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
1-Call Quitline Counseling, 4-Call Quitline Counseling, Nicotine patch, Nicotine Patch and Nicotine Lozenge, SmokefreeTXT, No SmokefreeTXT, Financial Incentives for Treatment Engagement, No Financial Incentives for Treatment Engagement
Behavioral · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,316 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Young Adult Tobacco/Nicotine and Cannabis Co-use

NCT06239350
View directory record Official record
Conditions
Tobacco Use Disorder, Nicotine Dependence
Interventions
Counseling, Contingency management, Text-based support
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 25 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Biomarkers in Children to Help Parents Quit Tobacco

NCT04832659
View directory record Official record
Conditions
Tobacco Dependence
Interventions
CEASE, CEASE + BIO
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
865 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 4 Interventional Results available

Tobacco Treatment Comparison for Cancer Care

NCT06218823
View directory record Official record
Conditions
Smoking Cessation, Cancer
Interventions
Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline, Cancer-Targeted Telephone Counseling, Mailed Information about Standard Care Resources
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 1 Interventional

Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers

NCT04194918
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Computer-Assisted Smoking Cessation Intervention, Text Message, Handout, Questionnaire Administration, Quality-of-Life Assessment, Survey Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining a Text Message Intervention for Smoking Cessation

NCT01166464
View directory record Official record
Conditions
Tobacco Use Disorder, Nicotine Dependence
Interventions
text messaging for smoking cessation, Generic text messages
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2014 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 4 Interventional Results available

Post-Discharge Smoking Cessation Strategies: Helping HAND 4

NCT03603496
View directory record Official record
Conditions
Smoking Cessation
Interventions
Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 1, 2026, 11:45 AM EDT
Completed Phase 4 Interventional Results available

BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study

NCT05683821
View directory record Official record
Conditions
Quitting Smoking, Smoking Cessation, Smoking, Cigarette
Interventions
Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral, Referral to Primary Care Provider, BREATHE 2 Cessation Study, Additional modalities to learn about and request treatment
Behavioral · Drug · Combination Product
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
12,376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 1, 2026, 11:45 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Beyond the Lung Cancer Diagnosis: Leveraging the Oncology Clinic Setting for Actively Smoking Family Members

NCT03966807
View directory record Official record
Conditions
Lung Cancer
Interventions
Digital-based support, Traditional-based support + Nicotine replacement therapy (NRT)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 1, 2026, 11:45 AM EDT
Recruiting Not applicable Interventional

Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos

NCT06926608
View directory record Official record
Conditions
Smoking, Smoking Cessation, Physical Inactivity
Interventions
Actívatexto, Decídetexto
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 1, 2026, 11:45 AM EDT