- Conditions
- Alcohol Use Disorder (AUD), PTSD
- Interventions
- CBT + expressive writing, Wait-List Control
- Behavioral
- Lead sponsor
- University of Rhode Island
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
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Showing 1–24
of 51
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Autism Spectrum Disorder
- Interventions
- The Emotion Awareness and Skills Enhancement Program, The Unified Protocol
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 10 Years to 30 Years
- Enrollment
- 470 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Tuscaloosa, Alabama • Pittsburgh, Pennsylvania
- Conditions
- Parkinsons Disease, Essential Tremor
- Interventions
- Biphasic DBS stimulation, Unified Parkinson's Disease Rating Scale, Tremor Rating Scale, Kinesia accelerometer, Trigno wireless system, GaitRite walking assessment.
- Device · Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Alcohol Use Disorder, Anxiety Disorders
- Interventions
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, Take Control
- Behavioral
- Lead sponsor
- Boston University Charles River Campus
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Depressive Disorders, Anxiety Disorders
- Interventions
- Unified Protocol for The Treatment of Emotional Disorders
- Behavioral
- Lead sponsor
- Palo Alto University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Los Altos, California
- Conditions
- Emotional Disorder
- Interventions
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents
- Behavioral
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 6 Years to 85 Years
- Enrollment
- 304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Interventions
- Brief Unified Protocol, Psychoeducation
- Behavioral
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 480 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Waco, Texas
- Conditions
- Suicidal Ideation, Suicide, Suicide Attempt
- Interventions
- Ecological momentary assessment (EMA), Treatment as usual (TAU), Brief skills sessions plus EMI skills practice prompts
- Behavioral
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Piscataway, New Jersey
- Conditions
- Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem, Emotional Disorder
- Interventions
- Unified Protocol for Emotional Disorders in Adolescents (UP-A)
- Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Coral Gables, Florida
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Interventions
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Depression, Anxiety, Mood
- Interventions
- Unified Protocol, Therapist Support
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder, Suicidal Ideation, Suicidal and Self-injurious Behavior
- Interventions
- Unified Protocol (UP), Treatment as Usual (TAU)
- Behavioral · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 26 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Misophonia
- Interventions
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, Revised Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Diabetes, Type 1 Diabetes
- Interventions
- Unified protocol for cognitive behavioral therapy (UP-CBT), Continuous Glucose Monitoring (CGM)
- Behavioral · Device
- Lead sponsor
- Albert Einstein College of Medicine
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • The Bronx, New York
- Conditions
- Alcohol Use Disorder, Post Traumatic Stress Disorder
- Interventions
- Cognitive Reappraisal, Psychoeducation
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Leeds, Massachusetts
- Conditions
- Bipolar Disorder, Anxiety Disorders
- Interventions
- UP CBT, Treatment as usual
- Behavioral · Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Emotional Distress, Anxiety, Depression
- Interventions
- Unified Protocol
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Heavy Drinking, Mental Health Issue
- Interventions
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 274 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Depression, Anxiety
- Interventions
- Unified Protocol for Adolescents (UP-A), Youth Outcomes Questionnaire, Treatment as Usual
- Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 2
- States / cities
- West Hartford, Connecticut • Coral Gables, Florida
- Conditions
- Anxiety Disorders, Mood Disorders
- Interventions
- Single Diagnosis Treatment Protocol, Unified Protocol (UP)
- Behavioral
- Lead sponsor
- Boston University Charles River Campus
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2017
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Interventions
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Behavioral
- Lead sponsor
- Shannon E. Sauer-Zavala
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Borderline Personality Disorder
- Interventions
- Countering Emotional Behaviors Module from Unified Protocol
- Other
- Lead sponsor
- Boston University Charles River Campus
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Misophonia
- Interventions
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, Process-based Cognitive Behavioral Therapy
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Anxiety Disorder, Posttraumatic Stress Disorder, Hazardous Drinking
- Interventions
- Unified Protocol- Alcohol, Usual care
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas