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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:09 AM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: The Zeltiq System Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fat Reduction in the Submandibular/Submental Area

NCT02700165
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outer Thigh Study With Varied Treatment Parameters

NCT02081209
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Marina del Rey, California • Pleasanton, California
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Feasibility of Producing the Appearance of a Gluteal Lift Post Cryolipolysis

NCT04553627
View directory record Official record
Conditions
Subcutaneous Fat
Interventions
ZELTIQ thermoelectric device
Device
Lead sponsor
Riverchase Dermatology
Other
Eligibility
22 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tissue Optimization on Cryolipolysis Procedures for Fat Layer Reduction

NCT01728857
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Reduction of Fat in the Flanks of Patients With Sharp Body Curvature

NCT01600638
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Extended Follow-Up Study for Subjects Who Participated in 2010 Study

NCT01579487
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Submental Study (Sequential Treatment Approach)

NCT03510598
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System, Kybella 20 MG in 2 ML Injection
Device · Drug
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A Pilot Study Testing a Noninvasive Cryolipolysis Device Versus a High Intensity Focused Ultrasound Device for Fat Reduction

NCT01976247
View directory record Official record
Conditions
Abdominal Fat
Interventions
High Intensity Focused Ultrasound Device, Noninvasive Cryolipolysis Device
Device
Lead sponsor
Northwestern University
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 18, 2026, 2:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

CoolSculpting the Flanks

NCT03304925
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
7
States / cities
Pleasanton, California • Sacramento, California • Chestnut Hill, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

EMS for Abdominal and Gluteal Muscle Toning

NCT03983304
View directory record Official record
Conditions
Non-Therapeutic Body Modification
Interventions
The ZELTIQ EMS System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
8
States / cities
Marina del Rey, California • Pleasanton, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting and RF for the Submental

NCT03873779
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study on the Submental Area

NCT01859091
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study of a Belt Applicator

NCT01767142
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System with Modified Belt Applicator
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Marina del Rey, California • Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting of the Distal Thigh Study

NCT02335749
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
4
States / cities
Miami, Florida • Chestnut Hill, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multiple CoolSculpting Treatment Study

NCT01814007
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
3
States / cities
Pleasanton, California • Walnut Creek, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting System

NCT04506307
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Marina del Rey, California • Pleasanton, California • Vista, California + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Targeted Fat Reduction of Pseudogynecomastia in the Male Breast Using the ZELTIQ Coolsculpting System

NCT01791660
View directory record Official record
Conditions
Gynecomastia
Interventions
Zeltiq Coolsculpting System
Device
Lead sponsor
Dermatology, Laser & Vein Specialists of the Carolinas
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects on Cellulite Appearance

NCT04876118
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years · Female only
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
6
States / cities
Scottsdale, Arizona • Los Angeles, California • Pasadena, California + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Functional Change With MMS

NCT04506502
View directory record Official record
Conditions
Muscle Weakness
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Reduction of Abdominal Fat

NCT01101997
View directory record Official record
Conditions
Fat Reduction
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
5
States / cities
Sacramento, California • Coral Gables, Florida • Hunt Valley, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting of the Flank With Alternate Treatment Parameters

NCT02081196
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Sacramento, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bilateral; Flank Study With Crown Cooling Insert

NCT02554760
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DualSculpting the Abdomen Using CoolSculpting

NCT02941146
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 18, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fat Layer Reduction in the Lateral Thighs Using CoolSculpting

NCT02324816
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Oct 18, 2026, 2:09 AM EDT