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ClinicalTrials.gov public records Last synced Sep 10, 2026, 9:48 AM EDT

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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Impact of LOFT Therapy™ on Breast Cancer Survivors

NCT02491957
View directory record Official record
Conditions
Breast Neoplasms
Interventions
LOFT Therapy
Other
Lead sponsor
Kathy Miller
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 12, 2018 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Following Hip Arthroscopy

NCT04113759
View directory record Official record
Conditions
Labral Tear, Glenoid, Femoral Acetabular Impingement
Interventions
Blood Flow Restriction Rehabilitative Therapy, Sham BFR Rehabilitative Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training and Blood Flow Restriction

NCT04938947
View directory record Official record
Conditions
Blood Flow Restriction and Low-Intensity Resistance Training
Interventions
Blood Flow Restriction Cuffs, Low-Intensity Resistance Training, High-Intensity Resistance Training
Device · Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 30 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional Results available

Blood Flow Restriction Following ACL Reconstruction

NCT03758755
View directory record Official record
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
Device · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Venous Distension Reflex and Orthostatic Hypertension

NCT03496792
View directory record Official record
Conditions
Blood Pressure
Interventions
Tilt + external pressure, Tilt + no external pressure., Limb occlusion + negative pressure, Limb occlusion + no negative pressure
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Active, not recruiting Not applicable Interventional

Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation

NCT05735236
View directory record Official record
Conditions
ACL Tear
Interventions
BFR Cuff
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
16 Years to 60 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Centennial, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Ischemic Conditioning to Enhance Function (I-C-FUN) in Children With Cerebral Palsy

NCT04598711
View directory record Official record
Conditions
Cerebral Palsy
Interventions
RLIC, Sham Conditioning, Muscle Power training, Balance training, Treadmill Training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
6 Years to 16 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet

NCT02592655
View directory record Official record
Conditions
Hemorrhage, Vascular Injury
Interventions
Pneumatic Tourniquet, One Windlass Tourniquet, Two Windlass Tourniquets, Tourniquet Tape 5 cm, Tourniquet Tape 10 cm
Device
Lead sponsor
Marcus Migura
Individual
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 10, 2026, 9:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Human Research Program Flight Thigh Cuff

NCT06476106
View directory record Official record
Conditions
Healthy
Interventions
Venoconstrictive Thigh Cuff (VTC)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

NCT05754632
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Knee Injuries, Quadriceps Muscle Atrophy
Interventions
Blood Flow Restriction using Delfi Personalized Tourniquet System
Device
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Therapy in Lower Limb Extensor Injuries

NCT04149977
View directory record Official record
Conditions
Lower Limb Injury
Interventions
Physical Therapy with pressure cuff, Physical Therapy with placebo pressure cuff
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 10, 2026, 9:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Tourniquet Pressure in Primary Total Knee Arthroplasty

NCT02830087
View directory record Official record
Conditions
Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
Interventions
Tourniquet Cuff Pressure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Bermuda Run, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 10, 2026, 9:48 AM EDT
Not listed Not applicable Interventional

Verticalization Robotic Exoskeleton DoC

NCT04833543
View directory record Official record
Conditions
Brain Injuries, Disorder of Consciousness
Interventions
Robotic Mobility Device (REX), Tilt Table
Other
Lead sponsor
Memorial Hermann Health System
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Strength Training in Female Runners With Patellofemoral Pain

NCT04480528
View directory record Official record
Conditions
Patellofemoral Syndrome
Interventions
Blood Flow Restriction Training (BFRT), Sham Blood Flow Restriction Training (Sham BFRT)
Other
Lead sponsor
Lauren Erickson
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Sep 10, 2026, 9:48 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Effects of Muscle Cooling on Motor Unit Firing of the Quadriceps

NCT07381920
View directory record Official record
Conditions
Healthy
Interventions
Cryotherapy
Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

NCT05586451
View directory record Official record
Conditions
Muscle, Acute Exercise
Interventions
Traditional High Load Resistance Exercise (HLRE), Low Load Resistance Exercise with Blood Flow Restriction (LLBFR), Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional

Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss

NCT05929508
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Ischemic Preconditioning
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

NCT06952543
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ultrasound Imaging
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise for Those With SCI

NCT04889092
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 10, 2026, 9:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Remote Ischemic Conditioning and Spinal Reflex Modulation

NCT06860464
View directory record Official record
Conditions
Healthy Young Adults
Interventions
Remote Ischemic Condtioning (RIC), Sham Conditioning, Balance training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 10, 2026, 9:48 AM EDT
Withdrawn Not applicable Interventional

Blood Flow Restriction Training Following Glenoid Labral Repair

NCT03675620
View directory record Official record
Conditions
Glenoid Labrum Tear
Interventions
BFR, Standard Rehabilitation
Device · Other
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 10, 2026, 9:48 AM EDT
Recruiting Not applicable Interventional

Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?

NCT03096366
View directory record Official record
Conditions
Quadriceps Atrophy, ACL Reconstruction
Interventions
Blood flow restriction, Physical therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 10, 2026, 9:48 AM EDT
Completed Not applicable Interventional Results available

Non-invasive Measurement of Cerebral Dynamic Autoregulation

NCT02442856
View directory record Official record
Conditions
Stroke
Interventions
Thigh Cuff
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 10, 2026, 9:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs

NCT06276673
View directory record Official record
Conditions
Blood Vessel Disease, Muscle Edema
Interventions
Delfi
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 10, 2026, 9:48 AM EDT