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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Think Twice: Treatment condition Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effectiveness of Telephone Versus Face-to-Face CBT in Treating People With Depression

NCT00498706
View directory record Official record
Conditions
Depression
Interventions
Telephone-administered cognitive behavioral therapy (T-CBT), Face-to-face administered CBT (FtF-CBT)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 16, 2013 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project

NCT03799341
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Group Based Exposure Therapy for Combat-Related PTSD

NCT00535223
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Based Exposure Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Male only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder

NCT05132699
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
Interventions
Cannabidiol (CBD) oral solution, Placebo, Massed Prolonged Exposure (mPE)
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 23, 2026, 8:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain

NCT05860205
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation
Behavioral · Other
Lead sponsor
Kailea Manning
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Changing Thought and Action in Tobacco Dependence With Transcranial Magnetic Stimulation

NCT00973622
View directory record Official record
Conditions
Tobacco Dependence
Interventions
repetitive transcranial magnetic stimulation (rTMS) 10 Hertz (Hz), repetitive transcranial magnetic stimulation (rTMS) 20Hz, SHAM repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
19 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2013 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Phase 1Phase 2 Interventional Results available

BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

NCT03496662
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
BMS-813160, Nivolumab, Gemcitabine, Nab-paclitaxel, Biopsy, Peripheral blood
Drug · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Phase 2 Interventional

Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevec

NCT00661180
View directory record Official record
Conditions
Chronic Myelogenous Leukemia
Interventions
Nexavar (Sorafenib, BAY43-9006)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Enduring Exercise Habits

NCT03634423
View directory record Official record
Conditions
Healthy
Interventions
Sweet Spot: Flexible high incentive condition, Sweet Spot: Flexible low incentive condition, Sweet Spot: Rigid high incentive condition, Sweet Spot: Rigid low incentive condition, FOTW: High incentive control condition, FOTW: Low incentive control condition, FOTW: High incentive treatment condition, FOTW: Low incentive treatment condition, Think Twice: Control condition, Think Twice: Treatment condition, WDR: Control condition, WDR: Treatment condition
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
32,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 23, 2026, 8:07 PM EDT
Active, not recruiting Phase 2 Interventional Results available

Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL

NCT03580928
View directory record Official record
Conditions
Chronic Lymphocytic Leukemia (CLL)
Interventions
Venetoclax, Obinutuzumab, Acalabrutinib
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Stamford, Connecticut • Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence

NCT01714050
View directory record Official record
Conditions
Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
Interventions
Cognitive-Behavioral Therapy (CBT), Light Therapy (LT)
Behavioral · Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Examining the Neural Effects of a Behavioral Intervention for Physical Activity in Multiple Sclerosis

NCT04496804
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Combining Acceptance and Commitment Therapy With Exposure and Response Prevention to Enhance Treatment Engagement

NCT03343106
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
ACT plus ERP, ERP alone
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Logan, Utah
Source: ClinicalTrials.gov public record
Updated Nov 16, 2017 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders

NCT03315208
View directory record Official record
Conditions
Substance Use Disorders, Depression, Anxiety, Emotional Disorder, Suicidal Ideation, Suicidal and Self-injurious Behavior
Interventions
Unified Protocol (UP), Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 23, 2026, 8:07 PM EDT
Recruiting Phase 2 Interventional

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

NCT05959434
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorder
Interventions
Cognitive Processing Therapy + Relapse Prevention, Relapse Prevention
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Charleston, South Carolina • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Phase 1 Interventional Results available

Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)

NCT00076245
View directory record Official record
Conditions
Seasonal Affective Disorder, Depression
Interventions
Light Therapy, Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life

NCT01009112
View directory record Official record
Conditions
Nightmares, Insomnia, Posttraumatic Stress Disorder
Interventions
PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 23, 2026, 8:07 PM EDT
Terminated Phase 2Phase 3 Interventional

Study to Evaluate Coconut Oil for Alzheimer's Disease

NCT01883648
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Coconut Oil Beverage, Placebo Beverage
Drug · Other
Lead sponsor
University of South Florida
Other
Eligibility
55 Years to 90 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart Rate Variability in Depression

NCT02525978
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Video Task, Imaginal Task
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Sep 23, 2026, 8:07 PM EDT
Active, not recruiting Phase 3 Interventional

Fluoxetine vs CBT in Childhood Anxiety Disorders

NCT04760275
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Fluoxetine, Cognitive Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
8 Years to 17 Years
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional

Mechanisms of Treatment Change in Panic Disorder and Agoraphobia

NCT03547180
View directory record Official record
Conditions
Panic Disorder With Agoraphobia
Interventions
Cognitive Therapy, Capnometry-Assisted Respiratory Training, In-vivo exposure
Behavioral
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 23, 2026, 8:07 PM EDT
Recruiting Not applicable Interventional

Mindfulness in Chronic Kidney Disease

NCT04099992
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Mindfulness-based stress reduction (MBSR), Health enhancement program (HEP), Transcutaneous Vagus Nerve Stimulation (tVNS), Sham-transcutaneous Vagus Nerve Stimulation (tVNS)
Behavioral · Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Phase 4 Interventional Results available

Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue

NCT03621761
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Telephone-based Cognitive Behavioral Therapy, Modafinil
Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 26, 2022 · Synced Sep 23, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Brief CBT Interventions Delivered by Nurse Care Managers to Improve Type 2 Diabetes Outcomes: Pilot Study

NCT02081573
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Brief CBT
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 23, 2026, 8:07 PM EDT