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ClinicalTrials.gov public records Last synced Sep 14, 2026, 5:01 PM EDT

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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Thrombus aspiration Clear all
Recruiting Not applicable Interventional

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

NCT07115940
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Endovascular Thrombectomy, Medical Management
Device · Other
Lead sponsor
Amrou Sarraj
Other
Eligibility
18 Years to 85 Years
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Chicago, Illinois • Kansas City, Kansas • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional

The Protrieve PROTECTOR Study

NCT06495996
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis
Interventions
Percutaneous mechanical thrombectomy (PMT)
Device
Lead sponsor
Inari Medical
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
15
States / cities
Newport Beach, California • New Haven, Connecticut • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed No phase listed Observational Results available

JETi Lower Extremity Venous Thrombosis

NCT07027878
View directory record Official record
Conditions
Venous Thrombosis
Interventions
JETi lower extremity venous thrombosis
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
21
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting Phase 4 Interventional

SUMMIT RISE Study of Acute Ischemic Stroke Patients

NCT07436156
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Route 92 Medical Reperfusion Systems
Device
Lead sponsor
Route 92 Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
West Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting No phase listed Observational

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

NCT06747117
View directory record Official record
Conditions
Lower Extremity Acute Limb Ischemia, LE ALI
Interventions
Indigo Aspiration System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
35
States / cities
Scottsdale, Arizona • San Diego, California • Ventura, California + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional

COMPASS Trial: a Direct Aspiration First Pass Technique

NCT02466893
View directory record Official record
Conditions
Ischemic Cerebrovascular Accident
Interventions
Adapt/Standard Stent Retriever (SR) Group
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2018 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

The Pivotal Study of RapidPulseTM Aspiration System

NCT06029491
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
RapidPulseTM Aspiration System
Device
Lead sponsor
RapidPulse, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
18
States / cities
Torrance, California • New Haven, Connecticut • Jacksonville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Phase 2 Interventional Results available

Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy

NCT00389467
View directory record Official record
Conditions
Stroke
Interventions
Merci Retriever and Penumbra System
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 85 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
21
States / cities
Los Angeles, California • San Diego, California • Santa Monica, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 14, 2026, 5:01 PM EDT
Completed No phase listed Observational Results available

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo Aspiration System

NCT04144959
View directory record Official record
Conditions
Lower Extremity Acute Limb Ischemia, LE ALI
Interventions
Indigo Aspiration System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
14
States / cities
Stanford, California • Danbury, Connecticut • Bradenton, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

NCT03876457
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Endovascular Thrombectomy, Medical Management
Device · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
19
States / cities
Los Angeles, California • Jacksonville, Florida • Chicago, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Sep 14, 2026, 5:01 PM EDT
Active, not recruiting Not applicable Interventional

BOLT-DVT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis

NCT05003843
View directory record Official record
Conditions
Deep Vein Thrombosis, DVT
Interventions
Indigo Aspiration System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
42
States / cities
La Mesa, California • Long Beach, California • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System

NCT04129125
View directory record Official record
Conditions
Ischemic Stroke, Acute Stroke
Interventions
Zoom Reperfusion System
Device
Lead sponsor
Imperative Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
28
States / cities
Huntsville, Alabama • Tucson, Arizona • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions

NCT01722877
View directory record Official record
Conditions
Restenosis, Peripheral Vascular Disease
Interventions
JetStream Navitus
Device
Lead sponsor
Midwest Cardiovascular Research Foundation
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Bettendorf, Iowa • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

SYMPHONY-PE Study for Treatment of Pulmonary Embolism

NCT06062329
View directory record Official record
Conditions
Acute Pulmonary Embolism, Thromboembolism, Emboli, Pulmonary, Thrombosis, Thrombus; Embolism, Embolism, Cardiovascular Diseases, Vascular Diseases
Interventions
Symphony Thrombectomy System
Device
Lead sponsor
Imperative Care, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
19
States / cities
Huntsville, Alabama • Los Angeles, California • Jacksonville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Safety and Efficacy of Thrombolysis in Combination With Endhole Aspiration in the Treatment of Acute DVT

NCT04297787
View directory record Official record
Conditions
Acute Deep Vein Thrombosis
Interventions
Thrombolysis in combination with endhole aspiration
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting No phase listed Observational

Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

NCT07335341
View directory record Official record
Conditions
Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis, Acute DVT of Lower Extremity, Chronic DVT of Lower Extremity, DVT, Deep Vein Thrombosis Leg, Thrombus in the Peripheral Venous Vasculature, Peripheral Arterial Disease, Acute Limb Ischemia, Lower Extremity Acute Limb Ischemia, LE ALI
Interventions
Liberant Thrombectomy System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Naples, Florida • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion Stroke

NCT07231380
View directory record Official record
Conditions
Acute Ischemic Stroke Patients, Large Vessel Occlusion
Interventions
Plunger Technique, Static Manual Aspiration Thrombectomy
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke

NCT01584609
View directory record Official record
Conditions
Acute Ischemic Stroke From Large Vessel Occlusion
Interventions
Penumbra System with Separator 3D, Penumbra System alone
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
8
States / cities
Newport Beach, California • Denver, Colorado • Hartford, Connecticut + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Phase 4 Interventional Results available

rtPA in in the Prevention of CVAD-Associated Thrombosis and Infection in Pediatric Patients With Short Bowel Syndrome

NCT02355743
View directory record Official record
Conditions
Short Bowel Syndrome
Interventions
rtPA lock therapy
Drug
Lead sponsor
Lynn Malec
Other
Eligibility
6 Months to 18 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Sep 14, 2026, 5:01 PM EDT
Recruiting No phase listed Observational

Aspiration Thrombectomy Using the Symphony or Prodigy System

NCT07350499
View directory record Official record
Conditions
Arterial Thromboembolism, Venous Thromboembolism, Pulmonary Embolism
Interventions
Prodigy Thrombectomy System, Symphony Thrombectomy System
Device
Lead sponsor
Imperative Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
8
States / cities
Huntsville, Alabama • Tampa, Florida • Naperville, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Antegrade Versus Retrograde IV for Blood Draws

NCT03533777
View directory record Official record
Conditions
There is no Focus on Any Specific Condition
Interventions
Peripheral intravenous catheter placement, Blood draw, Peripheral intravenous catheter, To keep open (TKO) infusion of 0.9% normal saline
Procedure · Other · Device + 1 more
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 90 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 30, 2019 · Synced Sep 14, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

The INFUSE - Anterior Myocardial Infarction (AMI) Study

NCT00976521
View directory record Official record
Conditions
Acute Anterior Myocardial Infarction
Interventions
Abciximab local infusion, No local infusion, Thrombus aspiration
Drug · Other · Procedure
Lead sponsor
Atrium Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
7
States / cities
Takoma Park, Maryland • Charlotte, North Carolina • Greensboro, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2013 · Synced Sep 14, 2026, 5:01 PM EDT
Enrolling by invitation Not applicable Interventional

Endovascular Therapy for Large Core Patients With Uncertain Response to Thrombectomy

NCT06961487
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute
Interventions
EndovascularThrombectomy, Endovascular thrombectomy with any FDA-approved device
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 14, 2026, 5:01 PM EDT
Completed No phase listed Observational

REal-World Analyses of Stroke - Thrombus Occlusion REtrieval

NCT04451525
View directory record Official record
Conditions
Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic
Interventions
MicroVention Mechanical Thrombectomy Devices as first-line treatment
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
Not listed
Enrollment
710 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
37
States / cities
Burbank, California • Carmichael, California • Redwood City, California + 34 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 14, 2026, 5:01 PM EDT