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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Thrust Manipulation - Thoracic Spine Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Thoracic Mobilization on Shoulder Range of Motion

NCT01518504
View directory record Official record
Conditions
Shoulder Range of Motion in Healthy Individuals
Interventions
Thoracic Mobilization, Sham
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 20, 2012 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain

NCT01862705
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spine manipulation
Other
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Results available

Assessment of Chiropractic Treatment Using Reaction and Response Times in Members of the Special Operation Forces (ACT2)

NCT02168153
View directory record Official record
Conditions
Physiological Measurements of Response and Reaction Times
Interventions
Chiropractic Manipulative Therapy, Wait-list
Other
Lead sponsor
RAND
Other
Eligibility
20 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 16, 2026, 8:56 PM EDT
Not listed Not applicable Interventional

The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain

NCT01760590
View directory record Official record
Conditions
Neck Pain, Cervical Pain
Interventions
Manual Manipulation, Mobilization
Procedure
Lead sponsor
Keystone Rehabilitation Systems
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Bridgeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Effects Cervicothoracic Manipulation Versus Passive Upper Trapezius Stretch

NCT02552290
View directory record Official record
Conditions
Neck Pain
Interventions
Upper Trapezius Stretch, Cervicothoracic manipulation, No intervention
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 16, 2015 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Short-Term Response of Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain

NCT02415660
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spinal manipulation, Trigger point dry needling, Cervical range of motion exercises, Posterior neck muscle activation exercise, Trigger point dry needling sham, Seirin J-type stainless steel needles, 0-2-0.3 x 40-50 mm
Procedure · Behavioral · Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Thoracic Spine Manipulation on Peripheral Neurodynamic Mobility

NCT02842918
View directory record Official record
Conditions
Musculoskeletal Manipulations
Interventions
Spinal Manual Therapy, Spinal Range of Motion
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02245425
View directory record Official record
Conditions
Neck Pain
Interventions
Supine Thoracic Spine Manipulation, Prone Thoracic Spine Manipulation
Other
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
22 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Sep 16, 2026, 8:56 PM EDT
Recruiting Not applicable Interventional

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

NCT06502951
View directory record Official record
Conditions
Cervicogenic Headache, Whiplash Injuries
Interventions
Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Manual Therapy on Shoulder Function

NCT04513535
View directory record Official record
Conditions
Musculoskeletal Manipulations, Shoulder, Range of Motion, Muscle Strength, Surface Electromyography
Interventions
Thoracic Manipulation, Cervical Manipulation, glenohumeral posterior glide mobilization, Sleeper stretch
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Phase 1Phase 2 Interventional

Cervicogenic Headache Dose-Response

NCT01530321
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Spinal Manipulation, Light Massage
Other
Lead sponsor
University of Western States
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomington, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Phase 2 Interventional

Development of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation

NCT00835302
View directory record Official record
Conditions
Shoulder Pain
Interventions
Cervicothoracic manipulation
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
6
States / cities
Aurora, Colorado • Boulder, Colorado • Greenwood Village, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial

NCT02708953
View directory record Official record
Conditions
Headache Disorders, Secondary
Interventions
Thoracic manipulation (Manipulation Group), Thoracic Manipulation (Control wait-list)
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Results available

Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis

NCT04972929
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Spinal Manipulation, Sham Spinal Manipulation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness

NCT06534931
View directory record Official record
Conditions
Muscle Weakness
Interventions
High velocity low amplitude thoracic spine manipulation, Sham
Procedure
Lead sponsor
University of New England
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 16, 2026, 8:56 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Validation of CPR for Manipulation for Neck Pain

NCT02287337
View directory record Official record
Conditions
Cervicalgia
Interventions
Manipulation, Exercise
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Phase 1 Interventional

Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization

NCT00504686
View directory record Official record
Conditions
Neck Pain
Interventions
manual therapy, exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 2, 2009 · Synced Sep 16, 2026, 8:56 PM EDT
Terminated Not applicable Interventional

Effect of Spinal Manipulation on Vulvar Pain

NCT04016467
View directory record Official record
Conditions
Vulvodynia, Perineal Pain, Vulvar Pain
Interventions
Thoracic manipulation, Sham thoracic treatment
Other
Lead sponsor
University of Mary Hardin-Baylor
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Copperas Cove, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 16, 2026, 8:56 PM EDT
Suspended Not applicable Interventional

A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02972710
View directory record Official record
Conditions
Neck Pain
Interventions
Supine thoracic spine thrust manipulation, Seated thoracic spine thrust manipulation
Other
Lead sponsor
Northern Arizona University
Other
Eligibility
20 Years to 50 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Manual Therapy and Exercise in Patients With Cervicogenic Headache

NCT01580280
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Thrust Manipulation, Non-thrust Mobilization and Exercise
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 13, 2014 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

NCT01318720
View directory record Official record
Conditions
Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Masefield and Cavallaro Physical Therapy
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Specific Effects of Manual Therapy

NCT03017534
View directory record Official record
Conditions
Musculoskeletal Manipulations, Placebo Effect
Interventions
Spinal Manual Therapy
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 16, 2026, 8:56 PM EDT
Not listed Not applicable Interventional

Thoracic Manipulation in Patients With Cervical Radiculopathy

NCT01495728
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
Thrust Manipulation - Thoracic Spine, Sham Manipulation
Procedure
Lead sponsor
Spine and Sport, Georgia
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 19, 2011 · Synced Sep 16, 2026, 8:56 PM EDT
Completed Not applicable Interventional

Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain in Dentistry Students

NCT01962090
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic Spine Thrust in Seated Position, Thoracic Spine Thrust in Supine Position
Other
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
22 Years to 45 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Sep 16, 2026, 8:56 PM EDT