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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Thrust Mobilization Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Mobilization in Conjunction With Exercise in Participants With a History of Chronic Ankle Instability

NCT03428620
View directory record Official record
Conditions
Ankle Sprains
Interventions
High Velocity Low Amplitude mobilization, Exercise protocol
Other
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Fayetteville, North Carolina • Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain

NCT02036905
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical and thoracic mobilization, cervical and thoracic manipulation
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Solon, Ohio • Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain

NCT01434966
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
Interventions
Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
Other
Lead sponsor
Creighton University
Other
Eligibility
15 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

The RELIEF Study - Researching the Effectiveness of Lumbar Interventions for Enhancing Function

NCT01854892
View directory record Official record
Conditions
Low Back Pain
Interventions
Manipulation, Mobilization, Laser Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 45 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Manual Therapy on Shoulder Function

NCT04513535
View directory record Official record
Conditions
Musculoskeletal Manipulations, Shoulder, Range of Motion, Muscle Strength, Surface Electromyography
Interventions
Thoracic Manipulation, Cervical Manipulation, glenohumeral posterior glide mobilization, Sleeper stretch
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Dry Needling and Manipulation vs. Mobilization, Exercise and Interferential Electrotherapy for Shoulder Impingement (Subacromial Pain Syndrome)

NCT03168477
View directory record Official record
Conditions
Subacromial Pain Syndrome
Interventions
dry needling, spinal manipulation, mobilization, exercise, modalities
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cockeysville, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 6, 2026, 2:52 PM EDT
Terminated Not applicable Interventional

Influence of Opioid Use on the Effects of Spinal Manipulative Therapy for Low Back Pain

NCT03749564
View directory record Official record
Conditions
Low Back Pain, Opioid Use
Interventions
SMT, Activation Exercises, Mobilizing Exercises, Extended SMT
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Sep 6, 2026, 2:52 PM EDT
Suspended Phase 2Phase 3 Interventional

Ankle Manual Therapy for Ankle Sprains

NCT00888498
View directory record Official record
Conditions
Sprains and Strains
Interventions
Passive Positioning, High-Velocity, Low-Amplitude Stretch, Slow, Mobilization Stretch
Other
Lead sponsor
University of the Pacific
Other
Eligibility
16 Years to 60 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2015 · Synced Sep 6, 2026, 2:52 PM EDT
Not listed Not applicable Interventional

Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain

NCT02619500
View directory record Official record
Conditions
Neck Pain
Interventions
Home Exercise Program, Patient advice, encouragement, and education, Thrust Manipulation, Non-thrust Mobilizations
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Sep 6, 2026, 2:52 PM EDT
Recruiting Not applicable Interventional

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

NCT06502951
View directory record Official record
Conditions
Cervicogenic Headache, Whiplash Injuries
Interventions
Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Phase 2 Interventional

Development of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation

NCT00835302
View directory record Official record
Conditions
Shoulder Pain
Interventions
Cervicothoracic manipulation
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
6
States / cities
Aurora, Colorado • Boulder, Colorado • Greenwood Village, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Phase 2 Interventional

Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain

NCT01092715
View directory record Official record
Conditions
Neck Pain
Interventions
Spinal mobilization, Massage, Neck exercises
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Mobilization Versus Manipulation for the Treatment of Cervicogenic Headaches

NCT03919630
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Thrust Mobilization, Non-Thrust Mobilizations
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

NCT05940012
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Phase 2 Interventional

Thrust Manipulation Versus Non-Thrust Manipulation

NCT01438203
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Thrust manipulation, Non-thrust manipulation
Procedure
Lead sponsor
Walsh University
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
North Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2012 · Synced Sep 6, 2026, 2:52 PM EDT
Not listed No phase listed Observational

Applying Pain Adaptability to Manual Therapy Practice

NCT05209659
View directory record Official record
Conditions
Musculoskeletal Manipulations, Low Back Pain
Interventions
Pragmatic Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Haslett, Michigan • Old Bridge, New Jersey • Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Sep 6, 2026, 2:52 PM EDT
Not listed Not applicable Interventional

Superficial Dry Needling for Cervicogenic Headache

NCT05444296
View directory record Official record
Conditions
Headache
Interventions
Superficial Dry Needling, Non-thrust Mobilizations only
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 10, 2022 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Manual Therapy and Exercise in Patients With Cervicogenic Headache

NCT01580280
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Thrust Manipulation, Non-thrust Mobilization and Exercise
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 13, 2014 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Phase 1 Interventional

Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization

NCT00504686
View directory record Official record
Conditions
Neck Pain
Interventions
manual therapy, exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 2, 2009 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Phase 3 Interventional

Mind Body Intervention for Chronic Lower Back Pain

NCT01894282
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
Manual Therapy, Mind Body Intervention
Procedure
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
18 Years to 69 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 6, 2026, 2:52 PM EDT
Completed Not applicable Interventional

Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents

NCT02111278
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham Manipulation, Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 6, 2026, 2:52 PM EDT
Not listed Not applicable Interventional

Prescriptive Mobilization Versus a Pragmatic Mobilization

NCT01940744
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Prescriptive Mobilization, Pragmatic Mobilization
Procedure
Lead sponsor
Walsh University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Des Moines, Iowa • North Canton, Ohio • Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2013 · Synced Sep 6, 2026, 2:52 PM EDT