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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Tibial nerve stimulation Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Posterior Tibial Nerve Stimulation vs. Sham

NCT00534521
View directory record Official record
Conditions
Overactive Bladder
Interventions
Posterior Tibial Nerve Device, Sham
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2007 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Pivotal Study of eCoin for Overactive Bladder With Urgency Urinary Incontinence

NCT03556891
View directory record Official record
Conditions
Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
Interventions
eCoin Tibial Nerve Stimulation
Device
Lead sponsor
Valencia Technologies Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
15
States / cities
Downey, California • Redwood City, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

eCoin Tibial Nerve Stimulation for OAB

NCT03029624
View directory record Official record
Conditions
Urgency Urinary Incontinence
Interventions
eCoin
Device
Lead sponsor
Valencia Technologies Corporation
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Newport Beach, California • Waterloo, Iowa • Greensboro, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 28, 2026, 3:08 PM EDT
Terminated Not applicable Interventional

Pulsed Electromagnetic Stimulation for Treatment of Overactive Bladder

NCT00805779
View directory record Official record
Conditions
Urinary Bladder, Overactive
Interventions
MagPro R30
Device
Lead sponsor
EMKinetics, Inc
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2011 · Synced Sep 28, 2026, 3:08 PM EDT
Completed No phase listed Observational

PTNS on Urinary and Global Quality of Life in MS Patients

NCT04063852
View directory record Official record
Conditions
Multiple Sclerosis, Lower Urinary Tract Symptoms, Neurogenic Bladder, Overactive Bladder, Urinary Incontinence, Urinary Urge Incontinence
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
23 participants
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 28, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

NCT05685433
View directory record Official record
Conditions
Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
Interventions
eCoin Tibial Nerve Stimulation
Device
Lead sponsor
Valencia Technologies Corporation
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
22
States / cities
Homewood, Alabama • Mobile, Alabama • Little Rock, Arkansas + 18 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Does Percutaneous Tibial Nerve Stimulation (PTNS) Improve Outcomes in Patients Presenting With Fecal Incontinence

NCT01274585
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Posterior tibial nerve stimulation (PTNS), Posterior tibial nerve stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 4, 2018 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electric Nerve Stimulation (TENS) for the Treatment of Nocturnal Enuresis in Children

NCT02900495
View directory record Official record
Conditions
Nocturnal Enuresis, Bedwetting
Interventions
transcutaneous electric nerve stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
5 Years to 18 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
5
States / cities
Albany, New York • Brooklyn, New York • New Hyde Park, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS

NCT02550561
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome
Interventions
Posterior Tibial Nerve Stimulation
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 28, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

NCT07136688
View directory record Official record
Conditions
Neurogenic Bladder Due to Spina Bifida
Interventions
Stamobil electric stimulator, sham tTNS device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
4 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional

Posterior Tibial Nerve Stimulation for Children With Pelvic Floor Dyssynergia

NCT06528470
View directory record Official record
Conditions
Constipation, Fecal Incontinence in Children, Pelvic Floor Dyssynergia
Interventions
Posterior Tibial Nerve Stimulation (PTNS), Sham Stimulation
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Active, not recruiting Not applicable Interventional

INTIBIA Pivotal Study

NCT05250908
View directory record Official record
Conditions
Urinary Incontinence, Urge, Urinary Bladder, Overactive, Urinary Bladder Diseases, Urologic Diseases, Lower Urinary Tract Symptoms, Urological Manifestations
Interventions
INTIBIA Therapeutic, INTIBIA Non-Therapeutic
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
22 Years to 80 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
20
States / cities
Beverly Hills, California • Los Angeles, California • Washington D.C., District of Columbia + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Tibial Nerve Stimulation: the ZIDA Device Equivalence

NCT04470765
View directory record Official record
Conditions
Overactive Bladder, Urge Incontinence, Urinary Incontinence, Urinary Frequency More Than Once at Night
Interventions
Zida
Device
Lead sponsor
Exodus Innovations
Industry
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 28, 2026, 3:08 PM EDT
Active, not recruiting No phase listed Observational

Qualitative Assessment of the Impact of TTNS on QOL and Participation

NCT04248322
View directory record Official record
Conditions
Neurogenic Bladder, Urinary Retention, Urinary Tract Infections, Spinal Cord Injuries
Interventions
Semi-structured interview
Behavioral
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

eCoin for OAB Feasibility Follow-on Study

NCT03655054
View directory record Official record
Conditions
Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
Interventions
eCoin Tibial Nerve Stimulation
Device
Lead sponsor
Valencia Technologies Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
Newport Beach, California • Waterloo, Iowa • Greensboro, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2022 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of eCoin at Sensory and Subsensory Amplitudes

NCT05882318
View directory record Official record
Conditions
Urge Incontinence
Interventions
eCoin Peripheral Neurostimulator System
Device
Lead sponsor
Valencia Technologies Corporation
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
7
States / cities
Downey, California • Fresno, California • Ankeny, Iowa + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 28, 2026, 3:08 PM EDT
Terminated Phase 4 Interventional Results available

Comparison of Combination Therapy vs Single Agent Therapy for Treatment of Urge Incontinence.

NCT02176642
View directory record Official record
Conditions
Urinary Urge Incontinence
Interventions
Oxybutynin extended release, Posterior Tibial Nerve Stimulation, Placebo
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Durham, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 28, 2026, 3:08 PM EDT
Terminated Phase 1 Interventional

Prospective, Multicenter Trial to Investigate the Safety and Efficacy of Percutaneous Tibial Nerve Stimulation for the Treatment of Fecal Incontinence

NCT01666405
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Urgent(R) PC Neuromodulation System
Device
Lead sponsor
Uroplasty, Inc
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
6
States / cities
Los Angeles, California • San Francisco, California • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced Sep 28, 2026, 3:08 PM EDT
Not listed Not applicable Interventional

Transcutaneous Tibial Nerve Stimulation for Urgency Urinary Incontinence

NCT04936464
View directory record Official record
Conditions
Urge Incontinence, Overactive Bladder
Interventions
transcutaneous tibial nerve stimulation (TTNS), transcutaneous electrical stimulation (TENS)
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TTNS vs PTNS in a County Hospital System.

NCT07353944
View directory record Official record
Conditions
Overactive Bladder
Interventions
Tibial nerve stimulation
Device
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

NCT07456865
View directory record Official record
Conditions
Urge Urinary Incontinence
Interventions
Altaviva™ system
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
14
States / cities
Homewood, Alabama • Idaho Falls, Idaho • St Louis, Missouri + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

Home Neuromodulation for Neurogenic Bladder Management in Spinal Cord Injury

NCT07264868
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Neurogenic Bladder (NB)
Interventions
iTNS, Sham iTNS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

PTNS Versus Sham Efficacy in Treatment of BPS

NCT02747420
View directory record Official record
Conditions
Interstitial Cystitis Bladder Pain Syndromes
Interventions
NURO TM, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 28, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Implantable Tibial Neuromodulation Pivotal Study (TITAN 2)

NCT05226286
View directory record Official record
Conditions
Overactive Bladder
Interventions
Medtronic Implantable Tibial Neuromodulation (TNM) System
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
29
States / cities
Homewood, Alabama • Cartersville, Georgia • Chicago, Illinois + 26 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 28, 2026, 3:08 PM EDT