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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:13 PM EDT

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Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Titanium Implant Clear all
Completed Not applicable Interventional

Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy

NCT01920139
View directory record Official record
Conditions
Focus: Breast Cancer With Axillary Node Metastasis
Interventions
Fine needle aspiration and core biopsy of lymph node, Axillary surgery, Titanium marker
Procedure · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 21, 2026, 6:13 PM EDT
Enrolling by invitation No phase listed Observational

Metallosis on Tissues and Serum Metal Levels in Children

NCT03359109
View directory record Official record
Conditions
Orthopedic Disorder, Retained Metal Implant
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
4 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2
States / cities
Rochester, Minnesota • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 21, 2026, 6:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Adjacent Segment Mechanics in Cervical Arthrodesis Patients

NCT03028402
View directory record Official record
Conditions
Intervertebral Disc Degeneration
Interventions
C5-C6 arthrodesis
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 60 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dental Hygiene and Peri-Implant Tissues Homeostasis

NCT03384446
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Tooth-borne treatment, Implant-specific treatment
Other
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
San Antonio, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 21, 2026, 6:13 PM EDT
Enrolling by invitation No phase listed Observational

Advanced Materials Science in XLIF Study

NCT03649490
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Hartford, Connecticut • Jacksonville, Florida • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

A Study of Dental Implants Coated With Bone Morphogenetic Protein

NCT00422279
View directory record Official record
Conditions
Alveolar Ridge Abnormality
Interventions
Nobel Replace Tapered Groovy
Device
Lead sponsor
Nobel Biocare
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 21, 2026, 6:13 PM EDT
Active, not recruiting No phase listed Observational

RETHINK REFLUX Registry

NCT04253392
View directory record Official record
Conditions
Gastroesophageal Reflux
Interventions
LINX Reflux Management System
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
21 Years to 99 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2032
U.S. locations
21
States / cities
Mobile, Alabama • Tucson, Arizona • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Fixation of Unstable Distal Radius Fractures

NCT00654615
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Intramedullary Radius Fixation (Micronail), Volar Plate Fixation
Device · Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects

NCT02015390
View directory record Official record
Conditions
Segmental Long Bone Defects
Interventions
Autogenous RIA bone grafting, Allogeneic bone grafting
Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair

NCT03247985
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
PROLENE Polypropylene Tacking Mesh, ProGrip Self-fixating Mesh
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 21, 2026, 6:13 PM EDT
Completed No phase listed Observational

Scoliosis Surgery Using the PASS® LP System

NCT01019109
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
Device
Lead sponsor
Medicrea, USA Corp.
Industry
Eligibility
Not listed
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
3
States / cities
Atlanta, Georgia • New Orleans, Louisiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Precision of Complete-arch Digital Implant Impressions With Intraoral Scanning Versus Photogrammetry

NCT05972148
View directory record Official record
Conditions
Edentulous Jaw
Interventions
Digital scanning, Photogrammetry
Other
Lead sponsor
William Negreiros
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Adherence of a Non-medicated Intravaginal Ring (IVR)

NCT01268332
View directory record Official record
Conditions
Healthy
Interventions
Non-medicated Intravaginal Ring
Drug
Lead sponsor
Population Council
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Birmingham, Alabama • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 21, 2026, 6:13 PM EDT
Recruiting Not applicable Interventional

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

NCT05936619
View directory record Official record
Conditions
Paralysis; Quadriplegic, Quadraplegia, Tetraplegia, Tetraplegic Motor Dysfunction Following Brainstem or Spinal Cord Injury, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis (ALS), Brainstem Stroke, Paralysis, Brain-computer Interface
Interventions
Mind Extender (MindEx)
Device
Lead sponsor
Nader Pouratian
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional

Volar Plate vs. Conventus DRS Fixation

NCT02390856
View directory record Official record
Conditions
Fractures, Closed
Interventions
Conventus DRS, Volar Plate
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Oct 21, 2026, 6:13 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

The Effects of Celecoxib on Bone Ingrowth

NCT00585156
View directory record Official record
Conditions
Bone Ingrowth, Pain
Interventions
Celecoxib
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 95 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 21, 2026, 6:13 PM EDT
Completed No phase listed Observational

Alveolar Bone Changes in Diabetes (ABCD) Study

NCT02395315
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Well-controlled diabetic (WC), Poorly controlled diabetics (PC)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
3
States / cities
Minneapolis, Minnesota • Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Phase 3 Interventional

rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study

NCT00707265
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
rhBMP-2/CRM/CD HORIZON® Spinal System, Autograft/CD HORIZON® Spinal System
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
463 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
28
States / cities
Phoenix, Arizona • Orange, California • Santa Monica, California + 25 more
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study of the Magnetic Anal Sphincter (FENIX System)

NCT01625221
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Magnetic Anal Sphincter
Device
Lead sponsor
Torax Medical Incorporated
Industry
Eligibility
19 Years to 84 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
2
States / cities
Minneapolis, Minnesota • Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Oct 21, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages

NCT03647501
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
Interventions
Interbody cage (titanium), Interbody cage (PEEK)
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 21, 2026, 6:13 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Carbon Fiber Implants

NCT03382041
View directory record Official record
Conditions
Tibial Shaft Fractures
Interventions
Carbon Fiber Implant, Titanium Implant
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 21, 2026, 6:13 PM EDT
Completed No phase listed Observational

Modulus in XLIF Study

NCT04418817
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Thousand Oaks, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 6:13 PM EDT
Active, not recruiting No phase listed Observational

A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis

NCT05197036
View directory record Official record
Conditions
Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
Interventions
Total Knee Arthroplasty
Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
12
States / cities
Atlanta, Georgia • Boston, Massachusetts • Novi, Michigan + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 6:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects

NCT00001211
View directory record Official record
Conditions
Ectodermal Dysplasia, Jaw, Edentulous
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1986 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 6:13 PM EDT