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ClinicalTrials.gov public records Last synced Oct 5, 2026, 5:58 AM EDT

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Showing 121–144 of 870 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Tobacco Cessation Clear all
Recruiting Phase 4 Interventional Accepts healthy volunteers

My Path to Quit Tobacco

NCT07419425
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, Quitline Counseling Phone Calls, Counseling Sessions, Pathways to Freedom, Monetary Incentive
Drug · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
1,550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
5
States / cities
Phoenix, Arizona • Indianapolis, Indiana • Kansas City, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Improving Negative Symptoms & Community Engagement in Veterans With Schizophrenia

NCT02469389
View directory record Official record
Conditions
Schizophrenia, Serious Mental Illness
Interventions
Engaging in Community Roles and Experiences (ENCoRE), Health & Wellness (H&W)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Post Acute Coronary Event Smoking Study

NCT01964898
View directory record Official record
Conditions
Smoking Cessation, Acute Coronary Syndrome
Interventions
Behavioral Activation (BA), Standard Smoking Cessation Counseling, Nicotine patch, Printed Self-help materials for Smoking Cessation
Behavioral · Drug · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery

NCT03091179
View directory record Official record
Conditions
Laryngologic Surgical Procedures
Interventions
THRIVE, Endotracheal tube
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 5, 2026, 5:58 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)

NCT04827420
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Mi Quit Care
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Varenicline or Nicotine Patch in Promoting Smoking Cessation Among Current Smokers

NCT01771627
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
varenicline, nicotine patch
Drug
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)

NCT01055886
View directory record Official record
Conditions
Smoking Cessation
Interventions
nicotine patch, placebo patch
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Oct 5, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation

NCT02432729
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Not listed
Lead sponsor
Philip Morris Products S.A.
Industry
Eligibility
30 Years to 65 Years
Enrollment
1,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Oct 5, 2026, 5:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

HIV-1 and Brain Interaction on Smoking Comorbidity

NCT03308331
View directory record Official record
Conditions
Smoking
Interventions
Tobacco smoking and nicotine patch
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 5, 2026, 5:58 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers

Influence of Tobacco Use on Cannabis Use

NCT03766971
View directory record Official record
Conditions
Cannabis Use, Tobacco Use
Interventions
7 days of Tobacco Cessation, 21 days of Tobacco Cessation, Cannabis
Behavioral · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Phase 4 Interventional Results available

Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms

NCT00332644
View directory record Official record
Conditions
Nicotine Dependence
Interventions
nicotine patch, nicotine lozenge, nicotine patch + nicotine lozenge, bupropion, bupropion + lozenge, placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,504 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 30, 2011 · Synced Oct 5, 2026, 5:58 AM EDT
Withdrawn Phase 2 Interventional

Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment

NCT02487953
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine patch, ENDS, Placebo patch, Placebo ENDS
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 5, 2026, 5:58 AM EDT
Not listed Phase 4 Interventional

Nicotine Treatment of Impulsivity in Parkinson's Disease

NCT01216904
View directory record Official record
Conditions
Parkinson's Disease
Interventions
nicotine patch, placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 14, 2013 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Multi-Media Approach to Partner Support in Smokeless Tobacco Cessation (UCare-ChewFree)

NCT01885221
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Multimedia Support Intervention
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 21, 2018 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents

NCT01651611
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources, Social support
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 79 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Web-based Smoking Cessation Program for Tribal College Students

NCT02050308
View directory record Official record
Conditions
Smoking Cessation
Interventions
Internet-All Nations Breath of Life (I-ANBL), Honoring the Gift of Heart Health, Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®
Other · Drug
Lead sponsor
Won Choi, PhD, MPH
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Kansas City, Kansas • Pablo, Montana
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Phase 2 Interventional

Very Low-Nicotine Cigarettes in Smokers With SUD

NCT01989507
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine, behavioral counseling for smoking cessation
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Enhancing a High School Based Smoking Cessation Program

NCT01145001
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Cognitive Behavioural Therapy, Contingency Management, Nicotine Transdermal Patch
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use

NCT04694846
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
Interventions
Nicotine Replacement, Bupropion Hydrochloride Controlled-release, Varenicline, Tobacco Cessation Counseling, Questionnaire Administration, Quality of Life Assessment, Best Practice
Drug · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Implementation of a System-level Tobacco Treatment Intervention

NCT02816697
View directory record Official record
Conditions
Smoking Cessation, Lung Cancer
Interventions
CEASE, Usual Care Tobacco Treatment Services
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Longitudinal Care: Smoking Reduction to Aid Cessation

NCT00309296
View directory record Official record
Conditions
Chronic Diseases
Interventions
smoking cessation
Behavioral
Lead sponsor
National Institutes of Health (NIH)
NIH
Eligibility
18 Years to 80 Years
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 14, 2011 · Synced Oct 5, 2026, 5:58 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

NCT03315910
View directory record Official record
Conditions
Smoking Cessation
Interventions
Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge, Message Framing, saliva sample
Behavioral · Drug · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
807 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
18
States / cities
Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 5, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Facebook Intervention for Young Sexual and Gender Minority Smokers

NCT03259360
View directory record Official record
Conditions
Tobacco Use, Smoking, Tobacco Dependence, Tobacco Use Disorder, Tobacco Use Cessation, Tobacco Smoking, Smoking Cessation, Smoking, Cigarette, Smoking, Tobacco
Interventions
POP:, TSP:
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 25 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Oct 5, 2026, 5:58 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Cannabis-Tobacco Co-Use Treatment Study

NCT06883162
View directory record Official record
Conditions
Tobacco Use Disorder, Tobacco Use Cessation, Cannabis Use, Cannabis Use Disorder, Marijuana Use
Interventions
Varenicline, Counseling, Psychosocial modules
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 5, 2026, 5:58 AM EDT