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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:22 AM EDT

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Showing 145–168 of 872 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Tobacco Cessation Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Relapse Following Involuntary Smoking Abstinence

NCT01374724
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Tobacco Use Ban, Tailored Pamphlet, Informational Pamphlet, Relapse Prevention Intervention
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
23,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
Memphis, Tennessee • Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?

NCT02825459
View directory record Official record
Conditions
Substance Withdrawal Syndrome
Interventions
Abstinence from e-cigarettes
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Phase 2 Interventional Results available

Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers

NCT01806779
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Chantix, Zyban, Nicotine patches
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
4
States / cities
Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2016 · Synced Oct 10, 2026, 1:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarker Feedback to Motivate Tobacco Cessation in Pregnant Alaska Native Women

NCT01605643
View directory record Official record
Conditions
Cancer, Tobacco Use, Pregnancy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
Up to 50 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Telephone Care Coordination for Smokers in VA Mental Health Clinics

NCT00724308
View directory record Official record
Conditions
Smoking
Interventions
Telephone Care Coordination, Telephone Care Coordination with state Quitline
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Smoking Cessation in Pediatric Primary Care

NCT01312480
View directory record Official record
Conditions
Tobacco Cessation, Media Use
Interventions
5A's Model, Media Use Assessment
Other
Lead sponsor
American Academy of Pediatrics
Other
Eligibility
14 Years to 25 Years
Enrollment
10,967 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Elk Grove Village, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Treatment Outreach to Reduce Disparities for Primary Care Populations

NCT01156610
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Tobacco Treatment
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
706 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2014 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Phase 3 Interventional

A Second Study of NicVAX/Placebo as an Aid for Smoking Cessation

NCT01102114
View directory record Official record
Conditions
Smoking Cessation
Interventions
NicVAX Vaccine, Placebo Vaccine
Biological
Lead sponsor
Nabi Biopharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
25
States / cities
Encino, California • Los Alamitos, California • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated May 9, 2012 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

NCT04367506
View directory record Official record
Conditions
Tobacco Cessation
Interventions
BecomeAnEX, Usual Care
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Phase 2 Interventional Results available

Effect of Galantamine on Short-term Abstinence

NCT01669538
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Galantamine, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional

Clinical Trial of an Automated Smartphone Based Smoking Cessation Treatment

NCT02930200
View directory record Official record
Conditions
Smoking Cessation
Interventions
Treatment as Usual, QuitGuide, Smart-T
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 10, 2026, 1:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial

NCT06145763
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Biospecimen Collection, Smoking Cessation Intervention, Survey Administration
Procedure · Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
776 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 10, 2026, 1:22 AM EDT
Recruiting Not applicable Interventional

Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

NCT06556238
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Metabolite Ratio
Other
Lead sponsor
Southcentral Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 10, 2026, 1:22 AM EDT
Withdrawn Not applicable Interventional

Contingency Management for Smoking Cessation in Pregnant Minority Women

NCT02195570
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Quit Smoking Now (QSN), Prize-based Contingency Management (CM)
Other · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

QuitAid Pilot Feasibility Trial

NCT05649241
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, Nicotine gum, Medication Therapy Management
Drug · Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional

Targeting Tobacco Cessation During Treatment for Cannabis Use Disorders

NCT01834794
View directory record Official record
Conditions
Cannabis Dependence
Interventions
MET/CBT/CM plus NRT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Concord, New Hampshire • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Quitting Study A Test of Pre-clinical Findings

NCT01824511
View directory record Official record
Conditions
Smoking
Interventions
Smokers cease smoking
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Hanover, New Hampshire • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 10, 2026, 1:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Project Impact: A Culturally-Tailored Adherence Intervention for Latino Smokers

NCT01811628
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Questionnaire, Interview
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Phase 2 Interventional

Tobacco Approach Avoidance Training for Adolescent Smokers-1

NCT01625767
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
AAT experiment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 21, 2013 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Phase 2 Interventional Results available

Topiramate to Aid Smoking Cessation in Alcohol Dependent Men

NCT00802412
View directory record Official record
Conditions
Nicotine Dependence, Alcohol Dependence
Interventions
Topiramate, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years · Male only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Early Phase 1 Interventional Results available

Pilot Study on Mindfulness for Tobacco and Alcohol in University Students

NCT01679236
View directory record Official record
Conditions
Nicotine Dependence, Alcohol Use
Interventions
Mindfulness Training for Smokers, Interactive Learning for Smokers
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 29 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Oct 10, 2026, 1:22 AM EDT
Active, not recruiting Not applicable Interventional

A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer

NCT07455513
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma, Malignant Thoracic Neoplasm
Interventions
Electronic Health Record Review, Informational Intervention, Interview, Referral, Smoking Cessation Intervention, Survey Administration
Other · Device
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional

Smoking Cessation in NYC

NCT04489524
View directory record Official record
Conditions
Smoking Cessation
Interventions
individualized counselor-led MI sessions, general health education session, NRT
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 110 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 10, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
View directory record Official record
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 10, 2026, 1:22 AM EDT