Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 23, 2026, 10:12 PM EDT

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Showing 1–24 of 146 matching trials from the live ClinicalTrials.gov search.
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Conditions
Smoking
Interventions
Active referral
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
2,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Tobacco Use, Smoking, Smoking Cessation
Interventions
Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Active, not recruiting Phase 3 Interventional

Optimizing Tobacco Use Treatment for PLWHA

NCT04176172
Conditions
HIV/AIDS, Nicotine Dependence
Interventions
Varenicline, Nicotine patch, Standard treatment, Standard treatment + Managed Problem Solving (MAPS) adherence intervention
Drug · Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Conditions
Tobacco Use
Interventions
Click City®: Tobacco, Usual Tobacco Curriculum
Other
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
9 Years to 12 Years
Enrollment
2,673 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Springfield, Oregon
Conditions
Smoking Cessation
Interventions
Smoking Cessation
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,830 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Effectiveness Trial of Project ALERT

NCT00650585
Conditions
Alcohol Drinking, Smoking, Marijuana Smoking
Interventions
Project ALERT
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
Not listed
Enrollment
8,338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

iCanQuit Smoking Cessation Among Hispanic Adults

NCT06811038
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch, Nicotine Lozenge, Survey Administration, Interview
Device · Drug · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
854 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions
Computer Screening, Brief Intervention, Referral toTreatment
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Leukemia, Liver Cancer, Lung Cancer, Pancreatic Cancer, Tobacco Use Disorder
Interventions
Smoking Prevention Usual Care, Counseling Intervention
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Houston, Texas
Conditions
Nicotine Dependence
Interventions
Sustained Care, Usual Care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Brief Tobacco Intervention in the US Military

NCT03196102
Conditions
Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe, Smoking, Hookah, Nicotine Dependence
Interventions
BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
2,999 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Interventions to Prevent Substance Abuse

NCT01482975
Conditions
Prevention Harmful Effects
Interventions
Tailored computer based intervention, Tailored computer intervention
Other
Lead sponsor
University of Rhode Island
Other
Eligibility
10 Years to 14 Years
Enrollment
4,158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Kingston, Rhode Island
Conditions
E-cigarette Use, Substance Use
Interventions
ENDS Prevention Intervention (TBD)
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
10 Years to 14 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Honolulu, Hawaii
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking Prevention Through Social Connections Among Adolescents - ASPIRE

NCT02703597
Conditions
Tobacco Use Behavior
Interventions
Surveys, ASPIRE, GSA-ASPIRE-Network
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 18 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Smoking, Sexual Behavior
Interventions
Linking Lives parent-based intervention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
Not listed
Enrollment
9,510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Completed Phase 1Phase 2 Interventional Results available

Healthy Heart Habits

NCT04158219
Conditions
Acute Coronary Syndrome, Depression
Interventions
Behavioral activation for health and depression (BA-HD)
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Phase 1 Interventional Accepts healthy volunteers

Wise Mind: Environmental Approach for Obesity Prevention

NCT00065039
Conditions
Healthy
Interventions
Promotion of a healthy diet and physical activity, Avoidance of Alcohol, Drugs, and Tobacco
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Phase 2 Interventional Accepts healthy volunteers

Exenatide for Smoking Cessation and Prevention of Weight Gain

NCT05610800
Conditions
Smoking Cessation, Weight Gain
Interventions
Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Conditions
Healthy Subject
Interventions
Preventive Intervention, Questionnaire Administration
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
13 Years to 18 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Conditions
Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use, Sexual Risk Behavior
Interventions
S4E, Attention-Matched Control Group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ypsilanti, Michigan
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers

NCT02596711
Conditions
Tobacco Use Cessation, Cancer Prevention
Interventions
Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test, Health Education and Handouts, Culturally Tailored Reading Materials, Counseling Sessions
Drug · Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of E-Cigarette Prevention Messages on Adolescents

NCT05985538
Conditions
Vaping Behavior
Interventions
Vaping prevention text messages, Wellness behaviors text messages
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Phase 3 Interventional Results available

Hutchinson Smoking Prevention Project

NCT00115869
Conditions
Smoking Among Youth
Interventions
Social-influences
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
7 Years to 9 Years
Enrollment
8,388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1984 – 1999
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Biospecimen Collection, Cognitive Assessment, Interview, Nicotine Replacement, Smoking Cessation Intervention, Survey Administration, Tobacco Cessation Counseling
Procedure · Other · Drug + 1 more
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 24 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Columbus, Ohio