- Conditions
- Decision Making, Executive Function, Dopamine
- Interventions
- Tolcapone 200 MG, Functional Magnetic Resonance Imaging (fMRI)
- Drug · Other
- Lead sponsor
- University of California, Berkeley
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Berkeley, California
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Showing 1–7
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- Conditions
- Alcohol Use Disorder
- Interventions
- Tolcapone, Placebo
- Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years to 40 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Transthyretin Amyloidosis, Amyloidosis, Leptomeningeal, Transthyretin-Related
- Interventions
- Tolcapone
- Drug
- Lead sponsor
- Boston University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Alcohol Use Disorder, Attention Deficit Hyperactivity Disorder
- Interventions
- Tolcapone, Placebo
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Frontotemporal Lobar Degeneration
- Interventions
- Tolcapone, Placebo
- Drug
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Brain Injuries, Brain Injuries, Traumatic, Brain Injury, Chronic
- Interventions
- Tolcapone 200 MG, Placebo
- Drug · Other
- Lead sponsor
- Sheppard Pratt Health System
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Towson, Maryland
- Conditions
- Obsessive-Compulsive Disorder
- Interventions
- Tolcapone 200 MG
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois