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Showing 1–6 of 6 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase 1 PK Study of Tolperisone in Healthy Subjects

NCT04465266
Conditions
Healthy
Interventions
Tolperisone
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Back Muscle Spasm, Back Pain, Back Strain, Back Spasm Upper, Muscle Spasm, Acute Pain
Interventions
Tolperisone Hydrochloride, Placebo
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
56
States / cities
Surprise, Arizona • Little Rock, Arkansas • Canoga Park, California + 51 more
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Driving Simulation to Assess Non-Sedative Effects of Tolperisone

NCT03353922
Conditions
Driving Impaired
Interventions
Cyclobenzaprine 10 Mg Oral Tablet, Placebo Oral Tablet
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Long Beach, California • Atlanta, Georgia
Completed Phase 2 Interventional Results available

Tolperisone in Acute Muscle Spasm of the Back

NCT03802565
Conditions
Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain, Muscle Cramp, Muscle Spasm, Low Back Pain
Interventions
Tolperisone, Placebo
Drug
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
43
States / cities
Huntsville, Alabama • Tempe, Arizona • Little Rock, Arkansas + 39 more
Conditions
Healthy
Interventions
Tolperisone Hydrochloride, Cyclobenzaprine Hydrochloride 10 MG, Placebo
Drug · Other
Lead sponsor
Neurana Pharmaceuticals, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Long Beach, California • Berlin, New Jersey
Conditions
Muscle Spasticity
Interventions
tolperisone HCl (AV650), Placebo
Drug
Lead sponsor
Avigen
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
9
States / cities
Pasadena, California • Miami, Florida • Atlanta, Georgia + 5 more