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ClinicalTrials.gov public records Last synced Oct 28, 2026, 10:44 AM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Tongue pressure Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain

NCT07095608
View directory record Official record
Conditions
Oral Cancer, Squamous Cell Carcinoma
Interventions
Pressure and stretch sensitivity testing
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.

NCT05798481
View directory record Official record
Conditions
Hypertension, Cardiovascular Diseases
Interventions
Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals.
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional

Study of Tongue Strengthening for Swallowing Problems

NCT01570023
View directory record Official record
Conditions
Dysphagia
Interventions
Isometric Progressive Resistance Oropharyngeal Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 95 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
9
States / cities
Evanston, Illinois • Lexington, Kentucky • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2015 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Early Phase 1 Interventional

Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)

NCT02710162
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Micro Mouth Pressure Meter, Iowa Oral Performance Instrument, Electrical Impedance Myography, Capsaicin, Videofluoroscopic Swallowing Study, Pulmonary Function Testing, Swallowing Related Quality of Life Questionnaire, Functional Oral Intake Scale, Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised, Eating Assessment Tool-10, Communicative Effectiveness Survey, The Center for Neurologic Studies Bulbar Function Scale
Device · Drug · Procedure + 1 more
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Oct 28, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

High Resolution Pharyngeal Manometry (HRPM) Biofeedback

NCT07508059
View directory record Official record
Conditions
Healthy
Interventions
Swallowing Maneuvers, High Resolution Pharyngeal Manometry (HRPM)
Other · Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional

Interventions for Patients With Alzheimer's Disease and Dysphagia

NCT03682081
View directory record Official record
Conditions
Dementia, Dysphagia, Alzheimer Disease
Interventions
Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI), Biotene Oral Balance Gel
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Improving Diagnostic Standards in Dysphagia

NCT04773184
View directory record Official record
Conditions
Dysphagia
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing, Videofluoroscopic Swallowing Study, Voluntary Peak Cough Flow Testing, Iowa Oral Performance Instrument, Capsaicin Challenge, Pulmonary Function Testing, Voicing Tasks
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 28, 2026, 10:44 AM EDT
Terminated Phase 3 Interventional

Apnex Clinical Study of the Hypoglossal Nerve Stimulation (HGNS®) System to Treat Obstructive Sleep Apnea

NCT01446601
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Hypoglossal Nerve Stimulation (HGNS) System (Apnex Medical )
Device
Lead sponsor
Apnex Medical, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
12
States / cities
Lenexa, Kansas • Topeka, Kansas • Louisville, Kentucky + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 28, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional

Tongue-strengthening Exercises in People With ALS.

NCT07295990
View directory record Official record
Conditions
ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis
Interventions
Isometric Lingual Strength Exercises
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional

The Impact of Post-Frenotomy Massages on Ankyloglossia Recurrence and Feeding Outcomes

NCT07738185
View directory record Official record
Conditions
Ankyloglossia
Interventions
Post-frenotomy massage
Other
Lead sponsor
Isaac Elijah
Other
Eligibility
Up to 1 Year
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Not yet recruiting Not applicable Interventional

Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial

NCT07736105
View directory record Official record
Conditions
Dysphagia, Critical Illness
Interventions
Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment
Device · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of High-resolution Manometry to Detect Upper Airway Obstruction During Sleep

NCT04139499
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Drug-induced sleep endoscopy (DISE), High-resolution manometry (HRM):
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
5 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 28, 2026, 10:44 AM EDT
Completed No phase listed Observational Results available

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

NCT03192358
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Parkinson Disease, Dysphagia
Interventions
Videofluoroscopic Swallowing Examination, Tongue Strength Measurement
Diagnostic Test · Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Pharyngeal Metrics to Predict Dysphagia Outcomes

NCT04569097
View directory record Official record
Conditions
Dysphagia, Swallowing Disorders
Interventions
standard of care lingual strengthening
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Hines, Illinois • Cincinnati, Ohio • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional

K01 Impacts of Lingual Endurance Exercise

NCT06072924
View directory record Official record
Conditions
Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke, Stroke
Interventions
Isotonic Endurance Exercise, Sham Exercise
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Obstructive Sleep Apnea and Arousal Threshold in Patients With Post-traumatic Stress Disorder

NCT02699138
View directory record Official record
Conditions
Sleep Apnea, Obstructive; Post-Traumatic Stress Disorders
Interventions
Trazodone, Placebo, Epiglottic catheter
Drug · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 28, 2026, 10:44 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Swallowing in OSA & CPAP Intolerance

NCT06786117
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Healthy
Interventions
SLP swallowing exercises, myofunctional exercises
Other
Lead sponsor
Denise Dewald
Other
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 28, 2026, 10:44 AM EDT
Enrolling by invitation Not applicable Interventional

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

NCT06430268
View directory record Official record
Conditions
Peri-Implantitis, Dental Implant Failed
Interventions
implant decontamination with titanium curette, implant decontamination with Air-Flow device
Procedure · Device
Lead sponsor
Andrea Ravida
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Metabolomic Profiling of Novel Mediators of Vascular Function

NCT00762242
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
blood sampling and brachial artery ultrasound
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ABVN Phase 1 - Vagal Maneuvers

NCT07881276
View directory record Official record
Conditions
Healthy Subjects
Interventions
Vagal Maneuvers, Multi-Electrode Array (MEA) Recording
Other · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

External Pharyngeal Exerciser and Dysphagia

NCT05708898
View directory record Official record
Conditions
Dysphagia
Interventions
Pharyngeal exerciser, sham pharyngeal exerciser
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 28, 2026, 10:44 AM EDT
Terminated Not applicable Interventional

Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke

NCT03969095
View directory record Official record
Conditions
Stroke, Dysphagia
Interventions
Tongue Pressure Resistance Training
Behavioral
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Wheaton, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional

Genioglossus Muscle Training for Snoring and Obstructive Sleep Apnea

NCT02834767
View directory record Official record
Conditions
Snoring, Sleep Apnea, Obstructive
Interventions
Genioglossis Strength Trainer, Placebo Genioglossis Strength Trainer
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 28, 2026, 10:44 AM EDT
Completed Not applicable Interventional Results available

Exercise for Swallowing Problems After Stroke

NCT00722111
View directory record Official record
Conditions
Cerebrovascular Accident, Deglutition Disorders
Interventions
lingual press, effortful swallowing, natural swallowing, non-oral sham (control) exercise
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Oct 28, 2026, 10:44 AM EDT