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ClinicalTrials.gov public records Last synced Sep 10, 2026, 3:18 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 4 Interventional Accepts healthy volunteers

A Twelve Week Study of Prototypes Mouth Rinses

NCT05526586
Conditions
Healthy
Interventions
Colgate Cavity Protection Toothpaste, Zero Alcohol Gum Prototype, Alcohol Gum Prototype, Listerine Cool Mint Antiseptic Mouthwash, 5% Hydroalcohol
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Malignant Pleural Mesothelioma
Interventions
E-Nose testing, Research blood
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
30 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Terminated Phase 2Phase 3 Interventional Results available

Prevention of Post-operative Pneumonia (POPP)

NCT01446874
Conditions
Post-operative Pneumonia, Lung Cancer, Esophageal Cancer
Interventions
0.12% chlorhexidine solution
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study

NCT03438045
Conditions
Oral Disease, Dental Caries
Interventions
Partnered intervention
Behavioral
Lead sponsor
NYU College of Dentistry
Other
Eligibility
18 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

NCT06242444
Conditions
Tooth Erosion
Interventions
Experimental Dentifrice, Placebo Control Dentifrice, Reference Dentifrice
Drug
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Eosinophilic Esophagitis
Interventions
swallowed sponge device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Results available

Clinical Evaluation of Oral Rinse for Xerostomia

NCT04289051
Conditions
Xerostomia
Interventions
HYDRAL Oral Rinse, BIOTENE® Oral Rinse, Placebo Oral Rinse
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.

NCT02753075
Conditions
Dentin Sensitivity
Interventions
Experimental Oral Rinse 1, Experimental Oral Rinse 2, Placebo Oral Rinse, Fluoride toothpaste
Device · Other · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss

NCT06515483
Conditions
Gingivitis, Supragingival Plaque
Interventions
Brushing and Flossing of teeth, Brushing Only
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed No phase listed Observational Accepts healthy volunteers

Meta-analysis of Stannous Fluoride and the Effects on Gingival Health

NCT03970759
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Positive control dentifrice, Negative control dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,890 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Imaging-based Assessment of Oral Biofilm and Gingival Health

NCT05470023
Conditions
Plaque, Dental, Gingivitis
Interventions
OTC Toothpastes or Mouthrinses
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Irvine, California
Completed Phase 4 Interventional Accepts healthy volunteers

Protocol Efficacy of Mouthwashes in Experimental Gingivitis

NCT07270952
Conditions
Gingivitis
Interventions
StellaLife, Chlorhexidine
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 35 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Stony Brook, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Affective Touch in Chronic Pain

NCT04206397
Conditions
Fibromyalgia
Interventions
affective touch
Behavioral
Lead sponsor
Laura Case
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Gingival Inflammation, Dental Caries
Interventions
Toothpaste Tablet, Conventional Toothpaste
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Loma Linda, California
Conditions
Depression, Anhedonia
Interventions
Enjoyable Activities Condition, Healthy Activities Condition
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tallahassee, Florida
Completed No phase listed Observational Accepts healthy volunteers

DECAMP-1: Diagnosis and Surveillance of Indeterminate Pulmonary Nodules

NCT01785342
Conditions
Lung Cancer
Interventions
Biosample and Imaging Collection
Other
Lead sponsor
Boston University
Other
Eligibility
45 Years and older
Enrollment
489 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Denver, Colorado + 9 more
Completed No phase listed Observational Accepts healthy volunteers

Pandemic-adapted Caries Care Multicentre Single-group Interventional Study

NCT04666597
Conditions
Dental Caries in Children
Interventions
Modified CariesCare International management
Procedure
Lead sponsor
Universidad El Bosque, Bogotá
Other
Eligibility
3 Years to 8 Years
Enrollment
409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana • Boston, Massachusetts
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Throat and Other HPV-Related Cancers in Men: Identifying Them Early

NCT02897427
Conditions
Human Papillomavirus Infection
Interventions
Biomarker Analysis, Biospecimen Collection, Ultrasonography
Other · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years to 64 Years · Male only
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Houston, Texas
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Assessing Gingivitis and Plaque From a Marketed Toothpaste

NCT07158112
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Whitter, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Internet-based Reiki for Tinnitus 2021

NCT04988399
Conditions
Tinnitus
Interventions
Reiki
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Study of Tooth Erosion in People With Esophagogastric Cancer

NCT05612048
Conditions
Esophagogastric Cancer
Interventions
Survey, Intra-oral camera, Optional Salvia sample
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Asthma
Interventions
Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage
Biological
Lead sponsor
Benjamin Medoff
Other
Eligibility
18 Years to 50 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride

NCT01563172
Conditions
Dental Caries
Interventions
Sodium fluoride / silica and carbopol, 0.5g, Sodium fluoride / silica and carbopol, 1.5g, Fluoride free dentifrice
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Dementia, Dysphagia, Alzheimer Disease
Interventions
Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI), Biotene Oral Balance Gel
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin