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Showing 145–168 of 208 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Lung-Resident Memory Th2 Cells in Asthma

NCT03455959
Conditions
Asthma, Allergic
Interventions
Bronchoscopy/BAL, Airway Brushing
Procedure
Lead sponsor
Andrew D. Luster, M.D.,Ph.D.
Other
Eligibility
18 Years to 55 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Interventional Accepts healthy volunteers Results available

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

NCT03421145
Conditions
Plaque
Interventions
3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse, Water
Device · Other
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

NCT06242444
Conditions
Tooth Erosion
Interventions
Experimental Dentifrice, Placebo Control Dentifrice, Reference Dentifrice
Drug
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Plaque Removal of a Novel Brushing Device

NCT05038293
Conditions
Dental Plaque
Interventions
Automated mouthpiece-based toothbrush, Manual toothbrush
Device
Lead sponsor
University of Washington
Other
Eligibility
5 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Completed Phase 4 Interventional Accepts healthy volunteers

A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing

NCT04750005
Conditions
Healthy
Interventions
Listerine Cool Mint, Colgate Cavity Protection Toothpaste, Reach Unflavored Waxed Dental Floss, American Dental Association (ADA) Ref Toothbrush
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years to 60 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Dental Caries
Interventions
0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice, 8.0% Arginine Dentifrice
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
10 Years to 14 Years
Enrollment
2,025 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
8
States / cities
Loma Linda, California • Gainesville, Florida • Indianapolis, Indiana + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

IFI16 is a Periodontitis Modulating Protein

NCT03513497
Conditions
Severe Periodontitis, Acute Inflammatory Response
Interventions
Customized acrylic mouthguard
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush, Cetylpyridinium Chloride (CPC), manual toothbrush
Drug · Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Completed Not applicable Interventional Results available

Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma

NCT01382446
Conditions
Ventilator Associated Pneumonia
Interventions
Chlorhexidine gluconate, Toothpaste
Drug · Other
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Plaque and Gingivitis Evaluation of a U-Shaped Toothbrush in a 30-Day Model

NCT06122376
Conditions
Plaque Induced Gingivitis
Interventions
U-shaped Power Toothbrush, Soft Manual Toothbrush
Device
Lead sponsor
Lander Enterprises, LLC
Industry
Eligibility
5 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions
Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection
Other · Procedure
Lead sponsor
Missouri Department of Health and Senior Services
Other
Eligibility
60 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jefferson City, Missouri
Conditions
Gingivitis, Plaque
Interventions
Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,145 participants
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Medication Adherence, Habits
Interventions
Habit workup, Standard Medication Counseling
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Waterloo, Iowa
Completed No phase listed Observational Accepts healthy volunteers

Meta-analysis of Stannous Fluoride and the Effects on Gingival Health

NCT03970759
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Positive control dentifrice, Negative control dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,890 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Leukemia
Interventions
Dental Procedure, Educational Intervention (prevention education), Interview, Survey Administration, Educational Intervention (one-on one education)
Procedure · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
3 Years to 12 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
ASD I, ASD2
Interventions
Hum by Colgate Smart Kids Toothbrush (battery powered) - 490000006871
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
5 Years to 12 Years
Enrollment
17 participants
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients

NCT07164989
Conditions
Gingivitis, DMFT Index, Dental Plaque Index, Oral Hygiene Education Methods, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment, Motivational Interview, OHI
Interventions
Motivational Interviewing-Based Counseling, Standard Oral Health Education
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 19 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Gingivitis, Gingival Bleeding, Dental Plaque
Interventions
Device: Electric Flosser, Manual toothbrush
Device
Lead sponsor
Flaus, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Noblesville, Indiana
Conditions
Ventilator Associated Pneumonia
Interventions
Toothbrushing only, Chlorhexidine only, Toothbrushing and Chlorhexidine
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
547 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Smoking, Lung Diseases
Interventions
Bronchopulmonary Lung Lavage, Bronchial Brushing, Bronchial Wall Biopsy
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional Results available

Cytosponge Protocol IRB 11-006429

NCT01585103
Conditions
Eosinophilic Esophagitis
Interventions
Cytosponge
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of Three Oral Care Regimens

NCT02940821
Conditions
Dental Plaque, Gingivitis
Interventions
Toothbrushing, Fluoridated Dentifrice (.15% sodium monofluorophosphate), Fluoridated Dentifrice Whitening System (.454% stannous fluoride with 2% hydrogen peroxide), Whitening (4.5% hydrogen peroxide), Other Fluoridated Dentifrice (.454% stannous fluoride)
Other
Lead sponsor
Pearl Network
Network
Eligibility
18 Years to 70 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Emerson, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Assess the Gingivitis Effects of Various Dentifrices

NCT06140771
Conditions
Gingivitis
Interventions
0.76% Sodium Monofluorophosphate Dentifrice, 1.15% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Whittier, California
Completed Not applicable Interventional Accepts healthy volunteers

Triclosan Toothpaste and Third Molar Surgery

NCT01292343
Conditions
Dry Socket, Wound Infection
Interventions
Colgate Total Toothpaste, Colgate Regular Toothpaste
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 35 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Rochester, New York