Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 141 matching trials from the live ClinicalTrials.gov search.
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Completed Not applicable Interventional Results available

Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs

NCT03733730
Conditions
Aphakia, Presbyopia, Astigmatism
Interventions
ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
2,449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Dothan, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Conditions
Myopia, Hyperopia, Astigmatism
Interventions
fanfilcon A, enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
17 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Berkeley, California
Conditions
Visual Acuity
Interventions
Toric Multifocal etafilcon A with PVP
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Terminated Not applicable Interventional Results available

Capsular Tension Rings in Intraocular Lens Rotation

NCT04436198
Conditions
Cataract, Ophthalmoplegia, Ophthalmologic Complication
Interventions
MORCHER® EYEJET® CTR Types 14, 14A, and 14C, Toric IOL Only
Device
Lead sponsor
Rachel Lieberman
Federal
Eligibility
30 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Completed Not applicable Interventional Results available

Evaluation of the Rotational Stability of the Tecnis Toric II IOL

NCT04327518
Conditions
Cataract, Corneal Astigmatism
Interventions
TECNIS® Toric II
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Bakersfield, California • Los Angeles, California • Sioux City, Iowa + 4 more
Conditions
Astigmatism
Interventions
Dailies Total1® contact lenses for astigmatism (T30fA)
Device
Lead sponsor
Scripps Poway Eyecare and Optometry
Other
Eligibility
18 Years to 45 Years
Enrollment
42 participants
Timeline
2023
U.S. locations
1
States / cities
San Diego, California
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
15
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 11 more
Conditions
Cataract
Interventions
Alcon Vivity toric intra ocular lens
Device
Lead sponsor
Kevin Barber
Other
Eligibility
45 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
DeLand, Florida
Conditions
Cataract
Interventions
The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
30 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sebring, Florida
Withdrawn No phase listed Observational

Revive Toric RWE Study

NCT06785194
Conditions
Astigmatism
Interventions
REVIVE samfilcon B custom toric contact lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Timeline
2026
U.S. locations
3
States / cities
Orange Park, Florida • Canton, Georgia
Conditions
Astigmatism
Interventions
DT1fA contact lenses
Device
Lead sponsor
Mann Eye Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
65 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses Phase 2

NCT03168542
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Orientation Characteristics of Daily Disposable Toric Contact Lenses

NCT06069609
Conditions
Astigmatism
Interventions
kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Rotation With a Multifocal Toric Contact Lens

NCT05433571
Conditions
Visual Acuity
Interventions
Test Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 2 more
Completed Not applicable Interventional Results available

Post-Market Evaluation of the EVO ICL

NCT05538754
Conditions
Myopia, Myopic Astigmatism
Interventions
EVO ICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Honolulu, Hawaii • Overland Park, Kansas • Omaha, Nebraska + 5 more
Conditions
Glaucoma, Cataract, Presbyopia
Interventions
Cataract Surgery with Implantation of Vivity Extended Range of Vision IOL
Procedure
Lead sponsor
Vance Thompson Vision
Other
Eligibility
45 Years and older
Enrollment
27 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kalifilcon A Toric Compared to Commercially Available Lenses

NCT06098937
Conditions
Astigmatism
Interventions
Kalifilcon Toric Lens, Total1 for Astigmatism, Precision1 for Astigmatism, MyDay Toric
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Results available

Postmarket Study of an Intraocular Lens Power Selection System

NCT03579433
Conditions
Cataract
Interventions
ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
9
States / cities
Mt. Dora, Florida • Panama City, Florida • Poughkeepsie, New York + 6 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses

NCT03150485
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Not yet recruiting Not applicable Interventional

Optimization for Toric Contact Lenses

NCT07557030
Conditions
Astigmatism, Ametropia
Interventions
Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A )
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3

NCT02950545
Conditions
Astigmatism
Interventions
Placebo Lenses, Spherical Lenses, Toric Lenses
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 39 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Astigmatism
Interventions
enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Irvine, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more