- Conditions
- Diabetic Foot Ulcer Outcome, Quality of Patient Care
- Interventions
- cellular and tissue based therapy, negative pressure wound therapy, debridement, advanced wound therapy, Nutritional screening, off-loading, Hyperbaric oxygen Therapy
- Biological · Device · Procedure + 1 more
- Lead sponsor
- U.S. Wound Registry
- Other
- Eligibility
- Not listed
- Enrollment
- 10,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 1
- States / cities
- The Woodlands, Texas
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Showing 1–24
of 28
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Diabetic Foot, Ulcer Foot
- Interventions
- Human split thickness skin allograft, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing
- Other
- Lead sponsor
- Professional Education and Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 5
- States / cities
- San Francisco, California • O'Fallon, Illinois • Youngstown, Ohio + 2 more
- Conditions
- Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Venous Leg Ulcer, Leg Ulcer, Leg Ulcers Venous, Ulcer
- Interventions
- Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Standard of Care VLU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU
- Other
- Lead sponsor
- BioLab Holdings
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 650 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Philidelphia, Pennsylvania
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Dressing Application, Offloading
- Procedure · Device
- Lead sponsor
- MiMedx Group, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 2
- States / cities
- Tulsa, Oklahoma • Roanoke, Virginia
- Conditions
- Diabetic Foot Ulcers
- Interventions
- Total Contact Cast, Instant Total Contact Cast (ITCC), Removable Cast Walker (RCW)
- Device
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 4
- States / cities
- Tucson, Arizona • Dallas, Texas • Temple, Texas
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Exercise
- Behavioral
- Lead sponsor
- Mercer University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
- Interventions
- Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing
- Other
- Lead sponsor
- PolarityTE
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Martinsville, Virginia
- Conditions
- Non-healing Wound, Non-healing Diabetic Foot Ulcer, Diabetic Foot Infection
- Interventions
- TTAX01, Surgical resection and debridement, Systemic antibiotics, Off-loading
- Biological · Procedure · Drug + 1 more
- Lead sponsor
- BioTissue Holdings, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Sylmar, California • Miami, Florida + 8 more
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Orion TM Amniotic Membrane Allograft, Standard of Care (SOC)
- Device · Procedure
- Lead sponsor
- Legacy Medical Consultants
- Industry
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 8
- States / cities
- Palm Springs, California • San Francisco, California • Vista, California + 5 more
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Transforming Powder Dressing, Standard of care topical wound agents and dressings
- Device · Other
- Lead sponsor
- ULURU Inc.
- Industry
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 12
- States / cities
- Washington D.C., District of Columbia • Winter Park, Florida • Baltimore, Maryland + 6 more
- Conditions
- Diabetic Foot Ulcer
- Interventions
- PEP (Purified Exosome Product) / TISSEEL
- Biological
- Lead sponsor
- Rion Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Blue Ash, Ohio
- Conditions
- Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
- Interventions
- Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU, Standard of Care - VLU, AM/Single - VLU, AM/Double - VLU
- Other
- Lead sponsor
- C5 Biomedical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 177 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Metairie, Louisiana
- Conditions
- Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
- Interventions
- Total Contact Soft Cast, Cam Boot
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Ulcer Foot, Leg Ulcer
- Interventions
- Standard of Care-DFU, AmnioCore - DFU, Amnio Quad-Core - DFU, Standard of Care-VLU, Amnio Tri-Core - VLU, Amniocore Pro +
- Other
- Lead sponsor
- Stability Biologics
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 324 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Circleville, Ohio
- Conditions
- Diabetic Foot Ulcers
- Interventions
- Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
- Combination Product
- Lead sponsor
- Omeza, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Toledo, Ohio
- Conditions
- Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
- Interventions
- Offloading, Additional (outer) Dressing Application, Mirragen Wound Matrix Dressing, Fibracol Wound Dressing
- Other
- Lead sponsor
- ETS Wound Care, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 5
- States / cities
- St Louis, Missouri • Youngstown, Ohio • Martinsville, Virginia + 2 more
- Conditions
- Neuropathic Diabetic Foot Ulcer
- Interventions
- MatriStem® [Urinary Bladder Matrix (UBM)], Mepilex® [Silicone foam dressing]
- Device
- Lead sponsor
- Calvary Hospital, Bronx, NY
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Foot Ulcer, Diabetic Foot
- Interventions
- Collagenase ointment, Modified Contact Cast System
- Drug · Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Tissue Engineered Skin Substitute, Offloading, Amnionic Membrane Graft
- Procedure · Device
- Lead sponsor
- Professional Education and Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 3
- States / cities
- Martinsville, Virginia • Roanoke, Virginia
- Conditions
- Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
- Interventions
- Mirragen Advanced Wound Matrix, Fibracol
- Device
- Lead sponsor
- ETS Wound Care, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 148 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 15
- States / cities
- Los Angeles, California • Pomona, California • San Francisco, California + 12 more
- Conditions
- Wound Heal, Ulcer
- Interventions
- InnovaMatrix® AC
- Device
- Lead sponsor
- ConvaTec Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 235 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 21
- States / cities
- Fresno, California • Los Angeles, California • San Diego, California + 16 more
- Conditions
- Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer
- Interventions
- TTAX01, Standard Care
- Biological · Other
- Lead sponsor
- BioTissue Holdings, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 16
- States / cities
- San Francisco, California • Sylmar, California • Miami, Florida + 13 more
- Conditions
- Diabetic Foot Ulcers, Diabetes
- Interventions
- Topical wound dressing, Human Amnion Allograft, usual wound care
- Device · Biological · Other
- Lead sponsor
- University of North Dakota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Grand Forks, North Dakota
- Conditions
- Diabetic Foot
- Interventions
- SkinTE, Control
- Biological · Other
- Lead sponsor
- PolarityTE
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 13
- States / cities
- Fresno, California • Los Angeles, California • Hollywood, Florida + 8 more