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ClinicalTrials.gov public records Last synced Oct 8, 2026, 5:43 PM EDT

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Showing 97–120 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Total Shoulder Arthroplasty Clear all
Completed Not applicable Interventional Results available

Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments

NCT01801241
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
Anatomic TSA using IRI Instrumentation, Anatomic Total Shoulder Arthroplasty
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional Results available

Impact of Humeral Component Version on Outcomes Following RTSA

NCT03111147
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
0 degrees humeral component version, 30 degrees humeral component retroversion
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 8, 2026, 5:43 PM EDT
Not yet recruiting No phase listed Observational

Three Year Outcomes After Shoulder Arthroplasty

NCT07815535
View directory record Official record
Conditions
Arthroplasty, Replacement, Shoulder, Arthritis Shoulder, Rotator Cuff Arthropathy
Interventions
Not listed
Lead sponsor
Vani Sabesan
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Atlantis, Florida • North Liberty, Iowa • Leawood, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Recruiting Not applicable Interventional

Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

NCT03921944
View directory record Official record
Conditions
Osteoarthritis of Shoulder
Interventions
CT scan of the shoulders
Diagnostic Test
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
45 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Active, not recruiting No phase listed Observational

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

NCT01480440
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3-and 4-part Proximal Humeral Fractures, Avascular Necrosis, Gross Rotator Cuff Deficiency, Revision Total Shoulder Arthroplasty
Interventions
Trabecular Metal Reverse Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • Egg Harbor, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

NCT04415931
View directory record Official record
Conditions
Shoulder Osteoarthritis, Cuff Tear Arthropathy, Massive Rotator Cuff Tear
Interventions
Local infiltration analgesia, Interscalene block
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

NCT02713230
View directory record Official record
Conditions
Pain
Interventions
bupivacaine liposome injectable suspension, Placebo
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Oct 8, 2026, 5:43 PM EDT
Recruiting Not applicable Interventional

Pectoralis Minor Release Versus Non-release in RSA

NCT06292169
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Tear Arthropathy, Advanced Glenohumeral Osteoarthritis
Interventions
Pectoralis Minor Release, RSA
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

NCT05005260
View directory record Official record
Conditions
Pain, Postoperative, Brachial Plexus Block
Interventions
Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 8, 2026, 5:43 PM EDT
Not listed Not applicable Interventional

Comparison Of A Novel Sling With A Traditional Abduction Sling After Shoulder Surgery

NCT05274737
View directory record Official record
Conditions
Rotator Cuff Tears, Osteo Arthritis Shoulders
Interventions
Novel sling, Traditional abduction sling
Device
Lead sponsor
Orthopedic Institute, Sioux Falls, SD
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 16, 2022 · Synced Oct 8, 2026, 5:43 PM EDT
Not yet recruiting Not applicable Interventional

Study on Outcomes of Proximal Humerus Fractures

NCT07060664
View directory record Official record
Conditions
Proximal Humerus Fracture
Interventions
open reduction internal fixation, intramedullary nail, reverse total shoulder arthroplasty
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 8, 2026, 5:43 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair

NCT03488433
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Interventions
Abduction brace, Antirotation sling
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Oct 8, 2026, 5:43 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Prospective Evaluation of Oral Antibiotics for Treatment of Shoulder PJI

NCT04636125
View directory record Official record
Conditions
Periprosthetic Infection, Oral Antibiotics, Revision Total Shoulder Arthroplasty
Interventions
Doxycycline 100 MG Oral Tablet
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 8, 2026, 5:43 PM EDT
Enrolling by invitation No phase listed Observational

MDR - Comprehensive Reverse/Versa Dial Ti Glenosphere

NCT04003272
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Arthritis, Shoulder Disease
Interventions
Comprehensive Reverse Versa-Dial Titanium Glenosphere
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2035
U.S. locations
2
States / cities
Louisville, Kentucky • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Physical Therapy After Reverse Total Shoulder Arthroplasty

NCT03547726
View directory record Official record
Conditions
Orthopedic Disorder
Interventions
Physical Therapy, Self-Rehab
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 8, 2026, 5:43 PM EDT
Enrolling by invitation Not applicable Interventional

Study of Zimmer Biomet Mymobility Application on Reverse Total Shoulder Arthroplasty (RTSA) Outcomes

NCT05789784
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty, Physical Therapy
Interventions
mymobility Physical Therapy, Standard Office-based Physical Therapy
Other
Lead sponsor
Campbell Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Palm Beach Gardens, Florida • Columbus, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional

Do Wound Protectors Reduce Contamination in Total Shoulder Arthroplasty?

NCT06513182
View directory record Official record
Conditions
Cutibacterium Acnes
Interventions
No Alexis orthopaedic protector, Alexis orthopaedic protector
Other · Device
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

NCT04968405
View directory record Official record
Conditions
Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Rheumatoid Arthritis Shoulder
Interventions
Catalyst CSR Total Shoulder System
Device
Lead sponsor
Catalyst OrthoScience
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
Royal Oak, Michigan • Portland, Oregon • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed Not applicable Interventional

The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty

NCT02692768
View directory record Official record
Conditions
Arthritis
Interventions
Live Music Therapy, Recorded Music Therapy, Control
Other
Lead sponsor
April Armstrong
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 8, 2026, 5:43 PM EDT
Recruiting Not applicable Interventional

A Study Comparing Shoulder Replacement Techniques For Patients With Shoulder Arthritis And An Intact Rotator Cuff

NCT07584356
View directory record Official record
Conditions
Shoulder Arthritis
Interventions
aTSA, rTSA
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Not yet recruiting Not applicable Interventional

A Trial to Assess the Safety and Effectiveness of an Anatomic Total Shoulder System

NCT07812324
View directory record Official record
Conditions
Shoulder Arthroplasty, Total Shoulder Arthroplasty
Interventions
Mirror Anatomic Total Shoulder Prosthesis, Medacta Anatomic Shoulder
Device
Lead sponsor
Medacta USA
Industry
Eligibility
22 Years and older
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
12
States / cities
Gilbert, Arizona • Boca Raton, Florida • Gulf Breeze, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 8, 2026, 5:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty

NCT05350319
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
A low-dose CT scan of the shoulder
Radiation
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 8, 2026, 5:43 PM EDT
Terminated No phase listed Observational

Clinical Evaluation of the TITAN™ Total Shoulder System

NCT03245320
View directory record Official record
Conditions
Arthritis, Arthritis, Degenerative, Rheumatoid Arthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Avascular Necrosis, Joint Instability, Joint Trauma, Dislocation, Shoulder, Pain, Shoulder
Interventions
Integra TITAN™ Total Shoulder Generation 1.0
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 8, 2026, 5:43 PM EDT
Withdrawn Phase 3 Interventional

Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty

NCT06638749
View directory record Official record
Conditions
Shoulder Arthritis, Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
Interventions
Tranexamic Acid, Normal Saline
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 8, 2026, 5:43 PM EDT