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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Total hip replacement Clear all
Completed No phase listed Observational

Preoperative Dietary Fat Consumption and Baseline Inflammatory Markers

NCT07442981
View directory record Official record
Conditions
Fat Consumption, Inflammatory Markers
Interventions
Inflammatory markers test in blood prior to surgery, Inflammatory markers test in CSF (cerebrospinal fluid), MOCA test, CAM-3D
Diagnostic Test
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
62 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.

NCT02127281
View directory record Official record
Conditions
Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
Interventions
Prevena
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Sep 17, 2026, 4:12 PM EDT
Active, not recruiting No phase listed Observational

Prospective G7 Dual Mobility Total Hip PMCF

NCT03308929
View directory record Official record
Conditions
Clinical Outcomes, Functional Outcomes, Radiological Outcomes, Survivorship, Safety
Interventions
G7 Dual Mobility hip
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
6
States / cities
Jersey City, New Jersey • Albuquerque, New Mexico • Chapel Hill, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Sep 17, 2026, 4:12 PM EDT
Terminated No phase listed Observational

28mm Ceramic-on-Ceramic Total Hip Replacement Study

NCT01657435
View directory record Official record
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
Interventions
Ceramax Acetabular System
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
Not listed
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
12
States / cities
Sacramento, California • Denver, Colorado • Fort Collins, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

NCT01121146
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Total Hip Replacement
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
Not listed
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2012
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 4, 2014 · Synced Sep 17, 2026, 4:12 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty

NCT02904993
View directory record Official record
Conditions
Degenerative Joint Disease
Interventions
L2 paravertebral block, periarticular injection group
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2016 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Aquacel Hypersensitivity Dressing in TJAs

NCT06011629
View directory record Official record
Conditions
Contact Allergic Dermatitis, Adverse Skin Reaction
Interventions
Aquacel dressing
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption

NCT03534102
View directory record Official record
Conditions
Opioid Use, Opioid Dependence, Knee Pain Chronic, Knee Osteoarthritis
Interventions
Improved Opioid-Tapering Instructions, Clinical Patient Educator
Drug · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 26, 2023 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Posterior Hip Precautions After Total Hip Arthroplasty

NCT03341442
View directory record Official record
Conditions
Osteoarthritis of Hip
Interventions
No hip precautions
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Knotless Suture in Revision Total Joint Arthroplasty

NCT04403919
View directory record Official record
Conditions
Arthroplasty
Interventions
Conventional Closure: Knee, Barbed suture closure: Knee, Conventional Closure: Hip, Barbed suture closure: Hip
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 17, 2026, 4:12 PM EDT
Enrolling by invitation Not applicable Interventional

Percussive vs. Gentle Massage for Recovery After Hip Replacement

NCT07790705
View directory record Official record
Conditions
Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
Interventions
Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
Device · Other
Lead sponsor
Zachary M Ricciardelli
Network
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cumming, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Oral Versus Intravenous Tranexamic Acid

NCT04089865
View directory record Official record
Conditions
Blood Loss, Blood Transfusion
Interventions
Tranexamic Acid
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 17, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional

Bikini vs Longitudinal Incision in Direct Anterior Approach (DAA) Total Hip Arthroplasty (THA)

NCT06831045
View directory record Official record
Conditions
THA
Interventions
Bikini Incision, Longitudinal Incision
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

NCT02242201
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
PNB Bupivacaine, PAI Ropivacaine, PAI liposomal bupivacaine, Epinephrine, Ketorolac
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Sep 17, 2026, 4:12 PM EDT
Recruiting No phase listed Observational

Z1 Hip System: Post-Market Clinical Follow Up Study

NCT07104279
View directory record Official record
Conditions
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
Interventions
Z1 Femoral Hip System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
4
States / cities
Charlotte, North Carolina • Cleveland, Ohio • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Terminated Not applicable Interventional Results available

Trident II Revision Outcomes Study

NCT04317586
View directory record Official record
Conditions
Arthroplasty, Hip Revision
Interventions
Trident II Tritanium Acetabular Shell for Revision
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
10
States / cities
Lafayette, Louisiana • New Orleans, Louisiana • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration

NCT02658240
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ropivacaine, Epinephrine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial

NCT00198003
View directory record Official record
Conditions
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Interventions
Educational program to address patients' expectations
Behavioral
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
55 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2011 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Early Phase 1 Interventional

Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty

NCT04437888
View directory record Official record
Conditions
Pain, Postoperative, Arthroplasty Complications
Interventions
Ketamine
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Phase 3 Interventional

Regulation of Coagulation in Orthopedic Surgery to Prevent DVT and PE, a Controlled, Double-blind, Randomized Study of BAY 59-7939 in the Extended Prevention of VTE in Patients Undergoing Elective Total Hip Replacement

NCT00332020
View directory record Official record
Conditions
Prevention, Venous Thromboembolism
Interventions
Rivaroxaban (BAY59-7939), Enoxaparin
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
2,457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
Birmingham, Alabama • Denver, Colorado • Bay Pines, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Sep 17, 2026, 4:12 PM EDT
Enrolling by invitation Phase 4 Interventional

Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

NCT07153003
View directory record Official record
Conditions
Post Operative Pain
Interventions
Oxycodone, Tramadol and Oxycodone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Completed No phase listed Observational

Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty

NCT01984190
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Not listed
Lead sponsor
Medical Compression Systems
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
10
States / cities
Little Rock, Alaska • La Jolla, California • Menlo Park, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 17, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional

Comparing Collared and Collarless Femoral Stems in Primary Total Hip Arthroplasty

NCT07337642
View directory record Official record
Conditions
Primary Total Hip Arthroplasty
Interventions
Collarless Femoral Stem, Collared Femoral Stem
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 17, 2026, 4:12 PM EDT
Completed Phase 4 Interventional Results available

TXA vs. Amicar in Total Knee and Hip Arthroplasty

NCT02030821
View directory record Official record
Conditions
Blood Loss, Hip Arthritis, Knee Arthritis
Interventions
Amicar, TXA
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 17, 2026, 4:12 PM EDT