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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Total hip replacement components Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Stability of Revision Total Hip Arthroplasty Implants Using Radiostereometric Analysis

NCT01668160
View directory record Official record
Conditions
Osteoarthritis of Hip, Failure of Primary THA
Interventions
Bead placement during revision hip replacement surgery
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 5, 2026, 10:15 PM EDT
Not listed Not applicable Interventional

Long-Term Multi-center Evaluation of E-Poly and Regenerex

NCT00545285
View directory record Official record
Conditions
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Interventions
Total Hip Arthroplasty
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 5, 2026, 10:15 PM EDT
Recruiting Not applicable Interventional

Influence of Antiseptic Washes on Wound Healing Complications After THA

NCT07104084
View directory record Official record
Conditions
Hip Osteoarthritis, Avascular Necrosis of Femur Head
Interventions
lavage chlorhexidine, lavage povidone-iodine
Device
Lead sponsor
F. Johannes Plate
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 5, 2026, 10:15 PM EDT
Completed No phase listed Observational

Wright Medical Technology Metal-on-Metal 522 Post-Market Surveillance Study

NCT03450733
View directory record Official record
Conditions
Osteoarthritis, Hip, Hip Disease, Hip Osteoarthritis, Joint Pain
Interventions
Wright Medical Technology Metal-on-Metal Total Hip System
Device
Lead sponsor
MicroPort Orthopedics Inc.
Industry
Eligibility
21 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
4
States / cities
El Cajon, California • La Mesa, California • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Phase 3 Interventional

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Total Hip Replacement Surgery

NCT00697099
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Semuloparin sodium, Enoxaparin sodium, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
2,326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 22, 2013 · Synced Sep 5, 2026, 10:15 PM EDT
Not listed Not applicable Interventional

Direct Anterior Versus Posterior Total Hip Arthroplasty Surgical Approaches

NCT01807494
View directory record Official record
Conditions
Osteoarthritis, Avascular Necrosis
Interventions
Total hip replacement components
Device
Lead sponsor
New Lexington Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Sep 5, 2026, 10:15 PM EDT
Not listed Not applicable Interventional

Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

NCT00551967
View directory record Official record
Conditions
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Interventions
Hip replacement
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 5, 2026, 10:15 PM EDT
Not listed No phase listed Observational

Origin Stem and Logical Cup Post Market Clinical Follow-up

NCT04123600
View directory record Official record
Conditions
Hip Disease
Interventions
Origin Stem and Logical Cup
Device
Lead sponsor
Signature Orthopaedics
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Sep 5, 2026, 10:15 PM EDT
Withdrawn Not applicable Interventional

Treatment of Acute Periprosthetic Total Hip Arthroplasty Infections

NCT01712880
View directory record Official record
Conditions
Periprosthetic Infection Total Hip Arthoplasty
Interventions
open debridement with modular exchange, one stage exchange
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Sep 5, 2026, 10:15 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Outcomes of Robotic Total Hip Arthroplasty

NCT01672320
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 5, 2026, 10:15 PM EDT
Completed No phase listed Observational Results available

Continuum™ Metal Bearing System in Total Hip Arthroplasty

NCT03382652
View directory record Official record
Conditions
Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic; Arthrosis, Total Hip Arthroplasty
Interventions
Metal-on-Metal Articulation
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2025 · Synced Sep 5, 2026, 10:15 PM EDT
Active, not recruiting Not applicable Interventional

Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty

NCT06792539
View directory record Official record
Conditions
Osteoarthritis of the Hip, Degenerative Joint Disease of Hip, Dysplasia; Hip
Interventions
Polymotion Hip Resurfacing (PHR) System
Device
Lead sponsor
JointMedica Inc.
Other
Eligibility
21 Years to 65 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
8
States / cities
Tampa, Florida • Chicago, Illinois • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional Results available

Comparing Total Hip Arthroplasty and Hemi-Arthroplasty on Secondary Procedures and Quality of Life in Adults With Displaced Hip Fractures

NCT00556842
View directory record Official record
Conditions
Hip Fractures, Femoral Neck Fractures
Interventions
Total hip arthroplasty, Hemi-arthroplasty
Device
Lead sponsor
McMaster University
Other
Eligibility
50 Years and older
Enrollment
1,495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 5, 2026, 10:15 PM EDT
Completed No phase listed Observational

THA With and Without Computer Navigation

NCT05871827
View directory record Official record
Conditions
Hip Osteoarthritis, Avascular Necrosis of Hip
Interventions
Intraoperative Fluoroscopic Computer Navigation
Procedure
Lead sponsor
Southeast Orthopedic Specialists
Network
Eligibility
18 Years to 95 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 5, 2026, 10:15 PM EDT
Not listed No phase listed Observational

Post Approval Study of the Commercially Available U-Motion II+ Acetabular System and UTF Reduced Stem

NCT02761499
View directory record Official record
Conditions
Osteoarthritis
Interventions
U-Motion II+ Acetabular System
Device
Lead sponsor
United Orthopedic Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
6
States / cities
Jacksonville, Florida • Naples, Florida • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Strength and Function Following Total Hip Arthroplasty

NCT01817010
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Multi-Component Rehabilitation (CMC), Control (CON)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced Sep 5, 2026, 10:15 PM EDT
Active, not recruiting Phase 4 Interventional

A Prospective Randomized Controlled Trial of Dual-Mobility Components in Primary THA

NCT03371212
View directory record Official record
Conditions
Serum Metal Levels, Specifically Cobalt, Chromium, and Titanium
Interventions
Dual mobility cohort, Conventional cohort
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional

Multicenter Study for Robotic Arm-assisted THA 4.0 System: Hip Spine Relationship

NCT04646096
View directory record Official record
Conditions
Osteoarthritis, Hip, Hip Disease
Interventions
MAKO THA 4.0 System
Device
Lead sponsor
American Hip Institute
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)

NCT02197273
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
Interventions
Liposomal bupivacaine, Standard of care analgesia
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2016 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Marathon and Enduron Polyethylene at Long-Term Follow-up

NCT02508428
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Interventions
Hip Replacement with crosslinked Marathon polyethylene, Hip Replacement with noncrosslinked Enduron polyethylene
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2017
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Trabecular Metal™ Revision Hip Cup Using Bone Mineral Density (DEXA)

NCT01183260
View directory record Official record
Conditions
Revision, Joint
Interventions
Trabecular Metal Revision Cup, Trabecular Metal Modular Cup
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 5, 2026, 10:15 PM EDT
Enrolling by invitation No phase listed Observational

Survivorship and Effectiveness of the Ortho Development® Entrada™ Hip System for Total Hip Arthroplasty

NCT04277416
View directory record Official record
Conditions
Total Hip Replacement, Total Hip Arthroplasty
Interventions
Total Hip Arthroplasty
Device
Lead sponsor
Ortho Development Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2032
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 5, 2026, 10:15 PM EDT
Active, not recruiting No phase listed Observational

Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA

NCT04325022
View directory record Official record
Conditions
Advanced Degeneration of the Hip Joint, Revision of the Hip Joint
Interventions
Primary Total Hip Arthroplasty, Revision Total Hip Arthroplasty
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2035
U.S. locations
6
States / cities
Lexington, Kentucky • Omaha, Nebraska • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 5, 2026, 10:15 PM EDT
Completed Phase 4 Interventional Results available

IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty

NCT03020966
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Acetaminophen
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 5, 2026, 10:15 PM EDT