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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:06 PM EDT

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Showing 289–312 of 941 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Total knee Clear all
Completed Not applicable Interventional Results available

Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C

NCT04953728
View directory record Official record
Conditions
IBS, Constipation
Interventions
Transcutaneous Electrical Acustimulation (TEA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Surgical Mask Use on Peak Torque, Total Work and Interset Fatigability During Isokinetic Strength Testing

NCT04706299
View directory record Official record
Conditions
Prevention of COVID-19
Interventions
Resistance Exercise
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Garfield Heights, Ohio
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated No phase listed Observational

Post Market Study of the 3DKnee™ With E-plus Insert

NCT01551472
View directory record Official record
Conditions
Degenerative Joint Disease, Osteoarthritis, Traumatic Arthritis
Interventions
3DKnee™ System with Vitamin E UHMWPE Tibial Inserts
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
40 Years to 75 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
6
States / cities
Burbank, California • Oceanside, California • Fort Myers, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional

Outcomes Following Tourniquet and Non-Tourniquet Assisted Total Knee Arthroplasty

NCT02203045
View directory record Official record
Conditions
Osteoarthritis
Interventions
Total Knee Arthroplasty
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 15, 2015 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated No phase listed Observational Results available

Study Comparing Fit of the iTotal Versus Standard Total Knee Implants

NCT01861028
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Atlantis, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 10, 2026, 1:06 PM EDT
Completed No phase listed Observational Results available

The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty

NCT05340751
View directory record Official record
Conditions
Anesthesia
Interventions
Blood drawn
Diagnostic Test
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
40 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Phase 4 Interventional Results available

Steroids in Bilateral Total Knee Replacement

NCT01399268
View directory record Official record
Conditions
Postoperative Inflammatory Response
Interventions
Hydrocortisone, Saline
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Phase 4 Interventional Results available

Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement

NCT01270620
View directory record Official record
Conditions
Obesity, Arthritis
Interventions
propofol, Desflurane
Drug
Lead sponsor
Pedro Paulo Tanaka
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Oct 10, 2026, 1:06 PM EDT
Not listed Phase 4 Interventional

Triamcinolone Ketorolac (TriKe) Knee Trial

NCT05336968
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Triamcinolone acetonide-Ketorolac-Ropivacaine
Drug
Lead sponsor
United Health Services Hospitals, Inc.
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Vestal, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Results available

Adductor Canal Block for Total Knee Arthroplasty

NCT02453360
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Pain, Postoperative
Interventions
Adductor Canal Block, Adductor Canal Block
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated No phase listed Observational

Prospective Functional Outcome Study of the Knee

NCT02079493
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Total Knee Arthroplasty
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Phase 3 Interventional

Acupuncture for Post-Thoracotomy Pain

NCT00142532
View directory record Official record
Conditions
Lung Cancer, Pain
Interventions
Acupuncture and Questionnaires, Placebo Acupuncture, Questionnaires
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2009 · Synced Oct 10, 2026, 1:06 PM EDT
Not yet recruiting Phase 4 Interventional

Suzetrigine vs. Standard Care Pain Relief Following Outpatient Knee Replacement Surgery

NCT07796152
View directory record Official record
Conditions
Knee Arthroplasty, Total, Post Operative Pain, Acute, Opioid Consumption, Postoperative
Interventions
Suzetrigine, Opioid standard care pain medicine
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Surgical and Economical Parameters of Total Knee Replacement.

NCT03427047
View directory record Official record
Conditions
Osteo Arthritis Knee, Total Knee Arthroplasty
Interventions
MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
Device
Lead sponsor
Medacta USA
Industry
Eligibility
16 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 13, 2023 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional

Tourniquet vs. no Tourniquet During Total Knee Arthroplasty

NCT02907047
View directory record Official record
Conditions
Osteoarthritis
Interventions
tourniquet inflated, tourniquet not inflated
Other
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Oct 10, 2026, 1:06 PM EDT
Recruiting Phase 1Phase 2 Interventional

Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

NCT06108063
View directory record Official record
Conditions
Knee Arthroplasty, Total
Interventions
Losartan, Placebo - Losartan
Drug
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Results available

Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty

NCT03016078
View directory record Official record
Conditions
Arthroplasties, Hip Replacement, Arthroplasties, Knee Replacement
Interventions
Mepilex Border Post-Op Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Gilbert, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Surgical Preparation Solutions in Knee Surgery

NCT01857349
View directory record Official record
Conditions
Arthroplasty, Replacement
Interventions
Chlora Prep, Dura Prep
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 89 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional Results available

Optimizing Physical Activity Outcomes After Total Knee Arthroplasty

NCT03226106
View directory record Official record
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Physical Activity Behavior Intervention, Attention Control
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated Not applicable Interventional

Health Partner Evaluation at Providence

NCT03443284
View directory record Official record
Conditions
Total Knee Arthroplasty; Total Hip Arthroplasty
Interventions
Health Partner, Standard Care
Behavioral
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Newberg, Oregon • Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 10, 2026, 1:06 PM EDT
Completed No phase listed Observational

An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool

NCT07120191
View directory record Official record
Conditions
Total Hip Replacement, Total Knee Replacement
Interventions
post op communication software
Device
Lead sponsor
Concentra AI, inc
Industry
Eligibility
22 Years to 80 Years
Enrollment
652 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Phoenix, Arizona • Wichita, Kansas • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated Not applicable Interventional

Manual Lymph Drainage

NCT02360735
View directory record Official record
Conditions
Total Knee Arthroplasty, Post-operative Edema
Interventions
Manual Lymphatic Drainage, Physical Therapy
Other
Lead sponsor
Anne Arundel Health System Research Institute
Other
Eligibility
45 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 10, 2026, 1:06 PM EDT
Terminated Phase 4 Interventional

iPACK Block With Dexamethasone For Total Knee Replacement

NCT04917055
View directory record Official record
Conditions
Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
Interventions
ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 10, 2026, 1:06 PM EDT
Completed Not applicable Interventional

Obturator Nerve Block With Femoral and Sciatic Block

NCT01409460
View directory record Official record
Conditions
Nerve Block; Pain Medication
Interventions
Oburator Nerve block, Sham Injection in pectineus muscle.
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2011 · Synced Oct 10, 2026, 1:06 PM EDT