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Showing 673–696 of 942 matching trials from the live ClinicalTrials.gov search.
Conditions
Osteoarthritis, Knee
Interventions
Ropivacaine Continuous Infusion, Ropivacaine Intermittent Bolus, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Total Knee Arthroplasty
Interventions
Blood Flow Restriction Training, Standard Physical Therapy
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
50 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Knee Osteoarthritis, Pain Management
Interventions
bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
6
States / cities
Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 3 more
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Conditions
Osteoarthritis
Interventions
Total Knee Robotically-Assisted
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 100 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Terminated No phase listed Observational

The Knee Usual Care Evaluation Study

NCT01905358
Conditions
Knee Osteoarthritis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
30 Years to 80 Years
Enrollment
906 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Knee Osteoarthritis
Interventions
Minimally invasive total knee replacement, Standard approach total knee replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Total Knee Arthroplasty
Interventions
Smartphone App, Control Group
Device · Combination Product
Lead sponsor
Lagniappe Physical Therapy
Other
Eligibility
45 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Shreveport, Louisiana
Conditions
Post-Operative Pain, Total Knee Arthroplasty
Interventions
Total knee arthroplasty (TKA), Cryoablation
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis, Post-Traumatic Arthritis, Rheumatoid Arthritis
Interventions
Scandinavian Total Ankle Replacement (STAR)
Device
Lead sponsor
Link America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2001
U.S. locations
5
States / cities
Jacksonville, Florida • Iowa City, Iowa • Kansas City, Kansas + 2 more
Conditions
Anesthesia
Interventions
Blood drawn
Diagnostic Test
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
40 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
New York, New York
Conditions
Total Knee Replacement, Primary Knee Arthroplasty
Interventions
Fentanyl, Ropivacaine
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Osteoarthritis, Knee
Interventions
TissueGene-C, Placebo
Biological
Lead sponsor
Kolon TissueGene, Inc.
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland • Arlington, Virginia
Conditions
Knee Arthritis, Hip Arthritis
Interventions
Wagner Pain Algometer, Dynamometer
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Lower Limb Deformity, Post-traumatic Deformity, Complications, Arthroplasty
Interventions
Vanguard XP Bicruciate Knee System, Vanguard CR Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
Chicago, Illinois • Salt Lake City, Utah
Conditions
Osteoarthritis, Knee
Interventions
Custom Patient Instrumentation, Conventional Instruments
Other
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Mooresville, Indiana • Bartlesville, Oklahoma • Reston, Virginia
Completed Not applicable Interventional Results available

A Study to Compare the NexGen CR and CR-Flex Knee Implants

NCT00761956
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
NexGen CR-Flex Fixed Bearing Knee, NexGen CR Knee
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years to 80 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
8
States / cities
Milford, Delaware • Chicago, Illinois • Rockford, Illinois + 5 more
Conditions
Hip or Knee Replacement
Interventions
'M'-Technique®, Guided Imagery, Standard of Care
Other
Lead sponsor
Saint Clare's Health System
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Denville, New Jersey
Conditions
Total Knee Replacement
Interventions
Weighted Blanket
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional Results available

Efficacy of AposTherapy® in Knee OA

NCT03153956
Conditions
Osteoarthritis, Knee
Interventions
Calibrated AposTherapy®, Non-Calibrated Sham Apos Therapy Device
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Recruiting No phase listed Observational Accepts healthy volunteers

HealthEast Community Hip and Knee Replacement Registry

NCT02692092
Conditions
Bone Fracture
Interventions
Not listed
Lead sponsor
HealthEast Care System
Other
Eligibility
18 Years and older
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 2091
U.S. locations
1
States / cities
Saint Paul, Minnesota
Completed Phase 4 Interventional Results available

Intraosseous Morphine in Primary TKA

NCT04388111
Conditions
Knee Disease, Arthritis Knee, Pain, Acute
Interventions
Morphine
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Conditions
Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Knee Arthritis
Interventions
Simplex® Bone Cement, Cobalt™ Bone Cement
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Warsaw, Indiana
Conditions
Anesthesia
Interventions
Audiovisual Distraction
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah