- Conditions
- Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant
- Interventions
- Not listed
- Lead sponsor
- AO Innovation Translation Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2027
- U.S. locations
- 4
- States / cities
- Columbia, Missouri • Jersey City, New Jersey • Livingston, New Jersey + 1 more
Search Results
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Showing 25–48
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- Conditions
- Acute Pain, Chronic Pain
- Interventions
- Dexamethasone, Placebo
- Drug · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases, Musculoskeletal Diseases, Edema Leg, Joint Pain, Arthritis Knee
- Interventions
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Device
- Lead sponsor
- Solventum US LLC
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 6
- States / cities
- Annapolis, Maryland • Baltimore, Maryland • Columbia, Maryland + 3 more
- Conditions
- Arthroplasty, Replacement, Knee, Total Knee Replacement
- Interventions
- X3 Polyethylene, N2Vac Polyethylene
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 518 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2023
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota
- Conditions
- Osteoarthritis, Knee
- Interventions
- Intravenous tranexamic acid, Topical tranexamic acid, Intravenous saline, Topical saline
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Replacement Surgery, Post-operative Pain
- Interventions
- Suzetrigine, Placebo
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 235 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anesthesia
- Interventions
- Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter
- Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty
- Interventions
- NEUROCUPLE™ Patch, Placebo Patch
- Device
- Lead sponsor
- nCap Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Acute Pain, Arthropathy of Knee, Arthropathy of Hip, Pain, Postoperative, Kidney Transplant Donor, Bariatric Surgery Candidate
- Interventions
- NSS-2 Bridge
- Device
- Lead sponsor
- Jacques E. Chelly
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 3
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis, RheumatoId Arthritis, Traumatic Arthritis, Polyarthritis
- Interventions
- Zimmer Persona Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 299 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 4
- States / cities
- Naperville, Illinois • Egg Harbor, New Jersey • Durham, North Carolina + 1 more
- Conditions
- Pain, Joint, Pain, Postoperative, Total Knee Arthroplasty
- Interventions
- CBD, Mineral Oil, Placebo
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Arthropathy of Knee
- Interventions
- OCSI Rehabilitator brace
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Knee Osteoarthritis, Arthroplasty, Replacement, Knee
- Interventions
- Educational program to address patients' expectations
- Behavioral
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 146 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2004
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteo Arthritis Knee
- Interventions
- Guardian Sport Rehabilitator knee brace
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Flexion Contracture, Total Knee Arthroplasty (TKA)
- Interventions
- Anterior heel wedge
- Device
- Lead sponsor
- University of North Carolina, Charlotte
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Total Knee Replacement
- Interventions
- DJO X4 brace with Motion Intelligence Platform
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Syosset, New York
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methadone
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Denver, Colorado
- Conditions
- Patellofemoral Knee Arthroplasty
- Interventions
- Robotically guided patellofemoral UKA isolated patellofemoral implants
- Device
- Lead sponsor
- St. Helena Hospital Coon Joint Replacement Institute
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2023
- U.S. locations
- 2
- States / cities
- St. Helena, California • Vancouver, Washington
- Conditions
- Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
- Interventions
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Device
- Lead sponsor
- Solventum US LLC
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 179 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 2
- States / cities
- Fishers, Indiana • Salt Lake City, Utah
- Conditions
- Osteoarthritis
- Interventions
- Bupivacaine, Morphine, Methylprednisolone, Cefazolin, Normal saline, Midazolam, Propofol, Dexamethasone, 8 MHz. Chiba needle, 22 G / 4 inches
- Drug · Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis
- Interventions
- GUIDED IMAGERY, PLACEBO
- Behavioral
- Lead sponsor
- Kent State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 82 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Akron, Ohio
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Not listed
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Lake Charles, Louisiana
- Conditions
- Total Knee Replacement
- Interventions
- Kneehab XP, Quadriceps TENS
- Device
- Lead sponsor
- Theragen Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Greenville, South Carolina
- Conditions
- Chronic Knee Pain
- Interventions
- Radiofrequency Ablation, Sham
- Device
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts