- Conditions
- Prosthetic-joint Infection, Dysbiosis
- Interventions
- Probiotic, Standard of care
- Drug · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • New York, New York
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Showing 1–24
of 474
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Total Knee Arthroplasty
- Interventions
- Hydrocortisone, Placebo
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Total Knee Replacement
- Interventions
- Ropivacaine injection, Saline Injection, Total Knee Arthroplasty
- Drug · Procedure
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Physical Activity
- Interventions
- Fitbit®, Physical Therapy Rehab
- Behavioral · Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Postoperative Pain, Inflammation, Osteoarthritis
- Interventions
- Dexamethasone 10 mg, Dexamethasone 20 mg, Standard multimodal pain management regimen, Placebo
- Drug
- Lead sponsor
- Thomas L Bradbury
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Tucker, Georgia
- Conditions
- Osteoarthritis, Postoperative Pain
- Interventions
- Whole blood for genotyping
- Genetic
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- TKA, THA, Anxiety, Binaural Beats, Music Exposure, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Total Knee Replacement, Total Hip Replacement
- Interventions
- Binaural Beats Audio Intervention, Music of Choice
- Other
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Interventions
- Avance Solo Negative Pressure Wound Therapy
- Device
- Lead sponsor
- Molnlycke Health Care AB
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 8
- States / cities
- Washington D.C., District of Columbia • Indianapolis, Indiana • Baltimore, Maryland + 5 more
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
- Interventions
- Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA, Local Infiltration Analgesia (LIA), Bupivacaine liposome injectable suspension (IPSA block), Bupivacaine liposome injectable suspension (LIA)
- Procedure · Drug
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Chronic Pain
- Interventions
- Observational
- Other
- Lead sponsor
- Wake Forest University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Osteoarthritis
- Interventions
- Omnibond Topical Skin Adhesive, Dermabond Advanced Topical Skin Adhesive
- Device
- Lead sponsor
- Center for Innovation and Research Organization
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 310 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- New York, New York • New Albany, Ohio • Philadelphia, Pennsylvania + 1 more
- Conditions
- Osteo Arthritis Knee
- Interventions
- Melatonin 5 mg, Placebo
- Drug · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
- Interventions
- ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Infection, Surgical Site
- Interventions
- Intraosseous Vancomycin Injection, Intravenous Vancomycin
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 19 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty, Total Knee Replacement
- Interventions
- Persona IQ
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- At-Home Monitoring
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Osteoarthritis, Knee
- Interventions
- Custom Patient Instrumentation, Conventional Instruments
- Other
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 3
- States / cities
- Mooresville, Indiana • Bartlesville, Oklahoma • Reston, Virginia
- Conditions
- Total Knee Replacement Surgery
- Interventions
- ultrasound guidance alone, ultrasound guidance and needle stimulation, ultrasound guidance and catheter stimulation
- Procedure
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 453 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Knee Osteoarthritis
- Interventions
- Compex Rehab
- Device
- Lead sponsor
- Orthopaedic Research Foundation
- Other
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Greenwood, Indiana
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Not listed
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Lake Charles, Louisiana
- Conditions
- Osteoarthritis, Knee
- Interventions
- Verasense
- Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 2
- States / cities
- Bronxville, New York • New York, New York
- Conditions
- Degenerative Arthritis of Knee
- Interventions
- VISIONAIRE Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Other
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 134 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 6
- States / cities
- Park Ridge, Illinois • Springfield, Illinois • St Louis, Missouri + 3 more
- Conditions
- Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
- Interventions
- SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
- Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Redwood City, California
- Conditions
- Osteoarthritis, Knee
- Interventions
- Total knee replacement
- Procedure
- Lead sponsor
- Fondren Orthopedic Group L.L.P.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Houston, Texas