Independent directory Public ClinicalTrials.gov records United States
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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Not applicable Interventional

TTVR Early Feasibility Study

NCT04433065
Conditions
Tricuspid Regurgitation
Interventions
Intrepid™ TTVR System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2031
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more
Conditions
Tricuspid Regurgitation, Tricuspid Valve Disease
Interventions
TricValve® Transcatheter Bicaval Valve System
Device
Lead sponsor
P+F Products + Features USA Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
36
States / cities
Phoenix, Arizona • Tucson, Arizona • San Diego, California + 31 more
Conditions
Severe Aortic Stenosis
Interventions
Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
Not listed
Enrollment
782 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
43
States / cities
Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 33 more
Conditions
Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure, Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency
Interventions
TricValve System, Optimal medical therapy
Device · Drug
Lead sponsor
P+F Products + Features USA Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
34
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sacramento, California + 29 more
Conditions
Tricuspid Regurgitation, Tricuspid Regurgitation Functional
Interventions
Trillium™
Device
Lead sponsor
Innoventric LTD
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
9
States / cities
Thousand Oaks, California • Detroit, Michigan • Rochester, Minnesota + 6 more
Conditions
Tricuspid Valve Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
inQB8 Medical Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
6
States / cities
Los Angeles, California • Thousand Oaks, California • Atlanta, Georgia + 3 more
Conditions
Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • Wichita, Kansas • Hackensack, New Jersey + 5 more
Conditions
Severe Tricuspid Regurgitation
Interventions
Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System, Edwards EVOQUE Tricuspid Valve Replacement (TTVR) System
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
1,186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2041
U.S. locations
4
States / cities
Phoenix, Arizona • Thousand Oaks, California • Minneapolis, Minnesota + 1 more
Active, not recruiting Not applicable Interventional Results available

2019-06 TRISCEND Study

NCT04221490
Conditions
Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
14
States / cities
Los Angeles, California • Stanford, California • Atlanta, Georgia + 9 more
Conditions
Tricuspid Regurgitation (TR)
Interventions
Transcatheter Tricuspid Valve Intervention
Device
Lead sponsor
Jenscare Innovation Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
3
States / cities
Los Angeles, California • Detroit, Michigan • New York, New York
Active, not recruiting Not applicable Interventional

TRISCEND II Pivotal Trial

NCT04482062
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
Interventions
Edwards EVOQUE System, Optimal Medical Therapy
Device · Drug
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
55
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 41 more
Conditions
Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders
Interventions
VDyne Transcatheter Tricuspid Valve Replacement System
Device
Lead sponsor
VDyne, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
10
States / cities
Los Angeles, California • Detriot, Michigan • Minneapolis, Minnesota + 7 more
Conditions
Tricuspid Regurgitation
Interventions
EVOQUE
Other
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
65 Years and older
Enrollment
2,044 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Irvine, California
Recruiting Not applicable Interventional

Trisol System EFS Study

NCT04905017
Conditions
Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
Trisol Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
7
States / cities
Los Angeles, California • Atlanta, Georgia • New York, New York + 4 more
Recruiting Not applicable Interventional

The TRICURE EFS Study

NCT06506942
Conditions
Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Interventions
Transcatheter Tricuspid Valve Replacement
Device
Lead sponsor
TRiCares
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
8
States / cities
Atlanta, Georgia • Chicago, Illinois • Ann Arbor, Michigan + 5 more
Conditions
Tricuspid Valve Regurgitation, Tricuspid Valve Disease, Cardiovascular Diseases (CVD), Heart Valve Diseases, Tricuspid Valve Insufficiency, Severe Heart Valve Disease, Randomized Controlled Trial (RCT), Symptomatic Tricuspid Regurgitation
Interventions
Transcatheter Tricuspid Valve Replacement (TTVR) with VDyne System, Transcatheter Tricuspid Valve Replacement (TTVR) with Edwards EVOQUE System
Device
Lead sponsor
VDyne, Inc.
Industry
Eligibility
18 Years and older
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Mitral Valve Regurgitation, Heart Failure, Heart Valve Disease, Tricuspid Valve Regurgitation, Aortic Valve Stenosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Tricuspid Regurgitation
Interventions
Laplace TTVR System
Device
Lead sponsor
Laplace Interventional, Inc
Industry
Eligibility
18 Years to 90 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
10
States / cities
Tucson, Arizona • San Francisco, California • Atlanta, Georgia + 7 more
Conditions
Tricuspid Regurgitation, Heart Failure, Structural Heart Disease, Interventional Cardiology
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York