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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:29 AM EDT

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Showing 289–312 of 532 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Transcranial direct current stimulation - Sham Clear all
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Modulation of Motor Cortex Excitability by TMS and tDCS (MAGS1)

NCT03481309
View directory record Official record
Conditions
Motor Activity, Motor Neuroplasticity
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional

Transcranial Direct-current Stimulation (tDCS) in Treatment Refractory Auditory Hallucinations

NCT03485131
View directory record Official record
Conditions
Auditory Hallucination, Schizophrenia
Interventions
Transcranial direct-current stimulation (tDCS), Placebo
Device
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cerebellar Involvement in Alcohol Use Disorder (AUD)

NCT05732207
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
cerebellar transcranial direct current stimulation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years to 55 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments

NCT05479006
View directory record Official record
Conditions
Stroke
Interventions
Transcranial direct current stimulation (high- definition)
Device
Lead sponsor
Carle Foundation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Enhancement Through Model-based and Individualized Neurostimulation

NCT06235970
View directory record Official record
Conditions
Transcranial Electrical Stimulation (tES)
Interventions
Transcranial electrical stimulation (tES) including SHAM
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

NCT05419999
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Soterix 1x1 tDCS mini CT, Sham Soterix 1x1 tDCS Mini CT, Written Exposure Therapy (WET)
Device · Other · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 17, 2026, 9:29 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TDCS to Improve Motivation and Memory in Elderly (TIME)

NCT04268186
View directory record Official record
Conditions
Motivation
Interventions
Direct tDCS, Indirect tDCS, Personalized tDCS, Sham tDCS
Device
Lead sponsor
Northeastern University
Other
Eligibility
65 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 17, 2026, 9:29 AM EDT
Terminated Not applicable Interventional Results available

Augmenting Exposure Therapy for Social Anxiety With Transcranial Direct Current Stimulation

NCT03743571
View directory record Official record
Conditions
Social Anxiety
Interventions
transcranial direct current stimulation, exposure therapy
Device · Behavioral
Lead sponsor
University of Nevada, Reno
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)

NCT05769348
View directory record Official record
Conditions
Chronic Migraine
Interventions
HD-tDCS Active Protocol, HD-tDCS Sham Protocol
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

NCT06843252
View directory record Official record
Conditions
Huntington Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

NCT05354232
View directory record Official record
Conditions
Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity
Interventions
2 mA transcranial direct current stimulation (tDCS), 1 mA transcranial direct current stimulation (tDCS), Sham transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TDCS for Auditory Hallucinations in Schizophrenia

NCT01898299
View directory record Official record
Conditions
Schizophrenia
Interventions
transcranial Direct Current Stimulation (tDCS), Sham tDCS
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
New York, New York • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Oct 17, 2026, 9:29 AM EDT
Active, not recruiting Not applicable Interventional

Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

NCT03625752
View directory record Official record
Conditions
Diabetic Neuropathies, Chronic Pain
Interventions
Active Comparator: Active tDCS + Active TUS, Sham
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
40 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 17, 2026, 9:29 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Evaluating Anodal tDCS Preceding Aphasia Therapy

NCT02249819
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional

Transcranial Direct Current Stimulation and Effects on Early Auditory Processing in Schizophrenia

NCT03537703
View directory record Official record
Conditions
Schizophrenia
Interventions
Active tDCS + Auditory Training, Active tDCS + Control Condition, Sham tDCS + Auditory Training
Combination Product
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 8, 2020 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

CogT BEEM Study (a tDCS Study)

NCT04099524
View directory record Official record
Conditions
Mild Cognitive Impairment, Neuropsychiatric Syndrome
Interventions
tDCS
Device
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional

tDCS and Physical Therapy in Stroke

NCT00542256
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Active transcranial Direct Current Stimulation / Constraint Induced Movement Therapy, Sham transcranial Direct Current Stimulation / Constraint Induced Movement Therapy
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

NCT04777149
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
Interventions
transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS), sham-stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery

NCT01539096
View directory record Official record
Conditions
Stroke
Interventions
tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT), Sham tDCS: placebo noninvasive brain stimulation
Procedure · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation

NCT03857529
View directory record Official record
Conditions
Stroke, Rehabilitation, Hand
Interventions
transcranial direct current stimulation and electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

Treating Primary Progressive Aphasia (PPA) Using tDCS

NCT04566731
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham tDCS, Modified Contraint-Induced Language Therapy (mCILT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 17, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

tDCS and Cognition in Adults With Multiple Sclerosis or Encephalitis

NCT02538094
View directory record Official record
Conditions
Multiple Sclerosis, Encephalitis
Interventions
Sham Transcranial direct current stimulation, Anodal Transcranial direct current stimulation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 17, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury

NCT05236010
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
rTMS, HD-tDCS, Attention Process Training
Device · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 59 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
5
States / cities
Minneapolis, Minnesota • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 17, 2026, 9:29 AM EDT