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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:33 AM EDT

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Showing 121–144 of 532 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Transcranial direct current stimulation - Sham Clear all
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

NCT05521074
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Terminated Not applicable Interventional Results available

tDCS and Cognitive Training Intervention for Chronic Smokers With Schizophrenia

NCT03588728
View directory record Official record
Conditions
Transcranial Direct Current Stimulation, Smoking, Cigarette, Schizophrenia
Interventions
Transcranial Direct Current Stimulation, Cognitive Remediation (CR)
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive Function

NCT03487601
View directory record Official record
Conditions
Breast Cancer, Fatigue
Interventions
transcranial direct current stimulation, sham transcranial direct current stimulation
Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 17, 2026, 1:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia

NCT02801864
View directory record Official record
Conditions
Aphasia, Language
Interventions
Real tDCS, Sham tDCS, Intensive Speech Therapy
Device · Other
Lead sponsor
Austin Speech Labs
Other
Eligibility
20 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 17, 2026, 1:33 AM EDT
Not listed Not applicable Interventional

Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy

NCT04934371
View directory record Official record
Conditions
Tinnitus, Subjective, Hyperacusis, Hearing Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham TDCS
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 17, 2026, 1:33 AM EDT
Terminated Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) in Post-Stroke Working Memory Deficits

NCT03034109
View directory record Official record
Conditions
Stroke, Cognitive Deficit, Cognitive Impairment, Short-Term Memory Impairment
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Oct 17, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Causal Role of the Aperiodic Signal for Working Memory

NCT06126809
View directory record Official record
Conditions
Executive Dysfunction
Interventions
Steep-tRAS, Flat-tRAS, Sham-tRAS
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

NCT04296604
View directory record Official record
Conditions
Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Attention Deficit Hyperactivity Disorder, Borderline Personality Disorder, Substance Use Disorders
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation

NCT03114488
View directory record Official record
Conditions
Healthy, Schizophrenia
Interventions
tDCS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 17, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

NCT05762796
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Not yet recruiting Not applicable Interventional

Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression

NCT07834762
View directory record Official record
Conditions
Treatment Resistant Depression (TRD), Major Depressive Disorder (MDD)
Interventions
Spaced Transcranial Direct Current Stimulation (tDCS), Sham Spaced tDCS
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Terminated Not applicable Interventional

Guided Imagery and Transcranial Direct Current Stimulation (tDCS) in Women With Chronic Pelvic Pain

NCT02781103
View directory record Official record
Conditions
Cystitis, Interstitial, Pelvic Pain
Interventions
Guided imagery plus active tDCS, Guided imagery plus Sham tDCS
Other
Lead sponsor
Kenneth M Peters, MD
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

tDCS Plus Virtual Reality for PTSD

NCT03372460
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Active stimulation, Sham stimulation, Virtual Reality (VR)
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Oct 17, 2026, 1:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Multi-focal tDCS on Motor-cognitive Dysfunctions in Parkinson's Disease

NCT02656316
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Tel-Aviv Sourasky Medical Center
Government
Eligibility
25 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Phase 2 Interventional Results available

Transcranial Direct Current Stimulation to Treat Symptoms of Parkinson's Disease

NCT00082342
View directory record Official record
Conditions
Parkinson Disease
Interventions
Phoressor II (IOMED)
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
40 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 27, 2012 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)

NCT06008431
View directory record Official record
Conditions
Fall, Gait, Unsteady, Mobility Limitation
Interventions
Transcranial direct current stimulation (tDCS) (active), Transcranial direct current stimulation (tDCS) (Sham)
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Neurosensory Account of Anxiety and Stress (Study 2)

NCT07079839
View directory record Official record
Conditions
Threat-related Sensory Cortical (SC) Disinhibition, Posttraumatic Stress Disorder (PTSD)
Interventions
Transcranial Alternating Current Stimulation (tACS), Sham for Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Pain Treatment in Gulf War Illness.

NCT03547869
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
45 Years to 78 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Dallas, Texas • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

Stimulating the Brain to Improve Self-Awareness

NCT03370341
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
active anodal tDCS, sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 55 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

A Study of HD-tDCS and Cognitive Training to Improve Cognitive Function in MCI

NCT04246164
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Memory Loss
Interventions
HD-tDCS combined with CT, sham HD-tDCS combined with CT
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Phase 1 Interventional

Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction

NCT04504344
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Quadriceps Muscle Weakness, Transcranial Direct Current Stimulation
Interventions
Anodal transcranial direct current stimulation (tDCS) - Soterix Medical Inc, 1x1 tDCS (conventional)
Device
Lead sponsor
Arcadia University
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Glenside, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2023 · Synced Oct 17, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation and Walking in Multiple Sclerosis

NCT03757819
View directory record Official record
Conditions
Transcranial Direct Current Stimulation
Interventions
tDCS, SHAM
Device
Lead sponsor
Thorsten Rudroff
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 17, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional

Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

NCT06801639
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 17, 2026, 1:33 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

tDCS for Cancer-Related Fatigue and Weakness

NCT07159100
View directory record Official record
Conditions
Cancer-related Fatigue, Neuromodulation
Interventions
Active tDCS + elbow flexion exercise, Sham tDCS + elbow flexion exercise
Device · Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
40 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 17, 2026, 1:33 AM EDT