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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Transcutaneous (Non-Invasive) Spinal Cord Stimulation Clear all
Completed Not applicable Interventional

Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI

NCT05091463
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Biostim-5/Neostim transcutaneous spinal stimulator
Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 12 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

NCT07504055
View directory record Official record
Conditions
Spinal Cord Injury, Orthostatic Hypertension, Autonomic Dysreflexia
Interventions
Spinal Cord Transcutaneous Stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Parkinson's Disease Rehabilitation

NCT06804642
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinal cord transcutaneous stimulation (scTS)
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2035
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

Using NI-ES to Treat Spinal Cord Injury (SCI)

NCT04097015
View directory record Official record
Conditions
Spinal Cord Injuries, Pain, Neuropathic
Interventions
Alpha-Stim M
Device
Lead sponsor
SCI Research Advancement
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Buellton, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

NCT06313515
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Arm-crank bike exercise, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Active, not recruiting Early Phase 1 Interventional

Transformation of Paralysis to Stepping

NCT04105114
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Buspirone, Non-invasive Spinal Cord Stimulation, Overground stepping, Gravity Neutral Device, Body Weight Supported Treadmill Training, Rolling Walker
Drug · Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Spatiotemporal tSCS in Spinal Cord Injury

NCT07397559
View directory record Official record
Conditions
Spinal Cord Injuries (SCI)
Interventions
No Stimulation, Conventional tSCS, Spatiotemporal tSCS
Other · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Transspinal Stimulation Plus Locomotor Training for SCI

NCT04807764
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
Interventions
Standing transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training, Standing sham transspinal stimulation followed by robotic gait training
Combination Product · Other
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Staten Island, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Cord Stimulation and Training

NCT05472584
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Electrophysiology assessment - spinal motoneuron, Activity-based training, Transcutaneous spinal cord stimulation
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury

NCT07204184
View directory record Official record
Conditions
Spinal Cord Injuries (Complete and Incomplete)
Interventions
Multisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
Device
Lead sponsor
Maria Knikou, PT, MBA, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury

NCT03184792
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Upper Extremity Dysfunction
Interventions
Transcutaneous spinal stimulation, Physical therapy
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Autonomic Effects of Stimulation in SCI

NCT05664646
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Transcutaneous Spinal Cord Stimulation (TSCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Neuromodulation to Enhance Motor Function in HSP

NCT07417943
View directory record Official record
Conditions
Hereditary Spastic Paraplegia
Interventions
transcutaneous spinal cord stimulation
Device
Lead sponsor
Rahul Sachdeva
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Terminated Not applicable Interventional

Activity-Dependent Transspinal Stimulation in SCI

NCT03669302
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
Interventions
Robotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
Other · Device
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Staten Island, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI

NCT06540859
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Sham Stimulation
Device
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 20, 2026, 7:42 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Cervical Transcutaneous SCS for TBI

NCT07147816
View directory record Official record
Conditions
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
Device
Lead sponsor
Roberto de Freitas
Other
Eligibility
21 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NCT01906424
View directory record Official record
Conditions
Paralysis, Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Los Angeles, California • San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 20, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

Trancutaneous Abdominal Stimulation on Bowel Function.

NCT04627168
View directory record Official record
Conditions
Spinal Cord Injuries, Constipation
Interventions
Non-invasive, surface electrical stimulation device, DS5 Digitimer
Device
Lead sponsor
Amol Soin, M.D., MBA
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2022 · Synced Sep 20, 2026, 7:42 PM EDT
Not listed Phase 1 Interventional

Non-invasive Electrical Spinal Cord Stimulation To Restore Upper Extremity Function in Multiple Sclerosis

NCT06552611
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Transcutaneous electrical spinal cord stimulation + therapy, Occupational Therapy
Combination Product · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia

NCT05157282
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
TESS, Training, Motor Task, sham-TESS
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 20, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing an EEG Probe for Studying and Modulating Cognitive Control

NCT05612659
View directory record Official record
Conditions
Post-stroke Depression
Interventions
Transcranial Electrical stimulation, Transcutaneous direct current stimulation
Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 20, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Stimulation for Neurological Populations

NCT04467437
View directory record Official record
Conditions
Neurological Disorder, Cerebral Palsy
Interventions
Gait Training, Transcutaneous Spinal Stimulation
Other · Device
Lead sponsor
University of Washington
Other
Eligibility
4 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 20, 2026, 7:42 PM EDT
Not listed Early Phase 1 Interventional

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

NCT06274021
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
Interventions
Transcutaneous spinal stimulation at 100 Hz, Transcutaneous spinal stimulation at 50 Hz, Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen, Transcutaneous spinal stimulation at 50 Hz and single dose of tizanidine, Sham transcutaneous spinal stimulation
Device · Combination Product
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 20, 2026, 7:42 PM EDT