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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Transcutaneous sensory nerve stimulation Clear all
Terminated Not applicable Interventional

Effect of Transcutaneous Electrical Auricular Stimulation of the Vagus Nerve in Kidney Transplant Recipients

NCT04256837
View directory record Official record
Conditions
Vagus Nerve Stimulation
Interventions
Transcutaneous electrical auricular vagus nerve stimulation (VNS)
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Electrotherapy on Pain, Anxiety, Motion and Disability in Adults With Neck or Upper Body Pain.

NCT05382039
View directory record Official record
Conditions
Chronic Pain
Interventions
Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
Loma Linda University
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Not yet recruiting Not applicable Interventional

BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)

NCT07659743
View directory record Official record
Conditions
Pain Management
Interventions
Active BreEStim Treatment, Sham BreEStim Treatment, The TENS Treatment
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
22 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation

NCT06892340
View directory record Official record
Conditions
Motion Sickness
Interventions
Transcutaneous Auricular Neurostimulation device
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation

NCT07199361
View directory record Official record
Conditions
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Interventions
Peripheral Transcutaneous Magnetic Stimulation from MagVenture
Device
Lead sponsor
Florida International University
Other
Eligibility
19 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 22, 2026, 3:14 PM EDT
Not yet recruiting Not applicable Interventional

Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral Neuropathy

NCT07822932
View directory record Official record
Conditions
HIV Associated Polyneuropathy
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation (AVNS)
Device
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects

NCT06361381
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Comparing the Effectiveness of the 'Think in Nerve Length and Layers' (TINLL) Approach to Traditional Treatment for Patients With Lateral Elbow Pain.

NCT07385677
View directory record Official record
Conditions
Lateral Elbow Tendinopathy (Tennis Elbow)
Interventions
TINLL techniques for relieving radial nerve tension, Traditional techniques to stretch and strengthen muscles
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Phase 1Phase 2 Interventional Results available

rTMS and Retraining in Focal Hand Dystonia

NCT01738581
View directory record Official record
Conditions
Focal Dystonia
Interventions
Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Corticospinal Excitability and Rehab in Knee Osteoarthritis

NCT02036866
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Transcutaneous Electrical Nerve Stimulation, Physical Therapy Exercises, No Intervention
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction

NCT04122703
View directory record Official record
Conditions
Female Sexual Dysfunction
Interventions
percutaneous tibial nerve stimulation (PTNS), Sham procedure
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional

Effects of Respiratory-Gated Transcutaneous Vagal Nerve Stimulation in Major Depression (Phase 1)

NCT04607226
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active transcutaneous vagus nerve stimulation, Sham transcutaneous vagus nerve stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
24 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

To Study the Mechanisms of Acupuncture Through Functional Magnetic Resonance Imaging and Peripheral Neurosensory Testing

NCT00521547
View directory record Official record
Conditions
Healthy
Interventions
Electroacupuncture
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2007 · Synced Sep 22, 2026, 3:14 PM EDT
Terminated Phase 4 Interventional Results available

Percutaneous Neuromodulation Therapy (PNT) With Chronic Low Back Pain Patients

NCT00290238
View directory record Official record
Conditions
Low Back Pain
Interventions
Vertis Percutaneous Neuromodulation Therapy (PNT), Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
RS Medical
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
La Jolla, California • Atlanta, Georgia • Eugene, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2009 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis

NCT05878873
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
Behavioral · Device
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 86 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS

NCT05500963
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Transcutaneous electrical nerve stimulation
Device
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Acute Pain on Cognitive Performance in Young Adults

NCT05625776
View directory record Official record
Conditions
Pain, Acute, Cognition
Interventions
pain delivery with capsaicin and heat, distractor delivery with sensory TENS
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Sep 22, 2026, 3:14 PM EDT
Terminated Phase 1Phase 2 Interventional

Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke

NCT03292159
View directory record Official record
Conditions
Stroke, Upper Extremity Paresis
Interventions
Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Cognitive Training to Enhance Brain Concordance During Acupuncture

NCT06157866
View directory record Official record
Conditions
Fibromyalgia
Interventions
Electroacupuncture, Cognitive Training, Education Training
Other · Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Charlestown, Massachusetts • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 22, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

NCT04908358
View directory record Official record
Conditions
Aging
Interventions
Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions, Sham transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years to 85 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect

NCT07157865
View directory record Official record
Conditions
Unilateral Spatial Neglect, Stroke
Interventions
Prism adaptation training combined with TENS, PAT only
Device · Other
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Centerville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Phase 2 Interventional

Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label

NCT07689773
View directory record Official record
Conditions
Olfactory Impairment
Interventions
Trigeminal Nerve Stimulation-enhanced Smell Training
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 22, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Vagus Nerve Stimulation for Attention and Memory

NCT06723743
View directory record Official record
Conditions
Traumatic Brain Injury (TBI) Patients
Interventions
Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT
Other · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
25 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 22, 2026, 3:14 PM EDT