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Showing 1–24 of 130 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Transcutaneous spinal cord stimulation Clear all
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Spinal Cord Associative Plasticity Study

NCT05163639
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions
Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Plus Spinal Stimulation for Cervical SCI

NCT04727866
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
Interventions
transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral, intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive BCI-controlled Assistive Devices

NCT05183152
View directory record Official record
Conditions
Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases, Motor Neuron Disease, Stroke, Traumatic Brain Injury, Movement Disorders, Multiple Sclerosis
Interventions
NMES Feedback, Visual Feedback, TESS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion

NCT05320432
View directory record Official record
Conditions
Abortion in First Trimester, Pain
Interventions
Transcutaneous electrical nerve stimulation (TENS), Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Spinal Cord Stimulation for the Treatment of Major Depressive Disorder

NCT03433339
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active transcutaneous spinal direct current stimulation, Sham transcutaneous spinal direct current stimulation
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI

NCT05091463
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Biostim-5/Neostim transcutaneous spinal stimulator
Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 12 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional

Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia

NCT03945331
View directory record Official record
Conditions
Paraplegia, Spinal, Paraplegia, Complete, Paraplegia; Traumatic
Interventions
Transcutaneous spinal cord stimulator, Epidural spinal cord stimulation system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 21, 2026, 6:09 PM EDT
Enrolling by invitation Not applicable Interventional

Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury

NCT06489106
View directory record Official record
Conditions
Spinal Cord Injury Cervical
Interventions
Activity based upper extremity training with and without stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
7 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Cervical Transcutaneous SCS for TBI

NCT07147816
View directory record Official record
Conditions
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
Device
Lead sponsor
Roberto de Freitas
Other
Eligibility
21 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Active, not recruiting Not applicable Interventional

Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity

NCT05669508
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
RISES-T System, Occupational/Physical Therapy
Device · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 55 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Combining tsDCS and Exoskeleton Gait Training on Spinal Excitability in SCI

NCT02862080
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
cathode tsDCS, Ekso, anode tsDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Sep 21, 2026, 6:09 PM EDT
Withdrawn Not applicable Interventional

Noninvasive Spinal Cord Stimulation for Neurogenic and Idiopathic Overactive Bladder

NCT03753750
View directory record Official record
Conditions
Overactive Bladder, Incontinence, Urge, Neurogenic Bladder
Interventions
Noninvasive spinal cord stimulation
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

NCT05265000
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
tSpinalStim
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

NCT05095454
View directory record Official record
Conditions
Paraplegia, Tetraplegia, Paralysis, Quadraplegia
Interventions
Percutaneous epidural electrical spinal stimulation, Transcutaneous electrical spinal stimulation
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
22 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Sep 21, 2026, 6:09 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI

NCT06698224
View directory record Official record
Conditions
Spinal Cord Injury, Spinal Cord Disease, Spinal Cord Injuries (SCI)
Interventions
Spinal cord transcutaneous stimulation, Paired spinal cord and peripheral nerve stimulation
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing Non-Invasive Spinal Stimulation Devices

NCT07217314
View directory record Official record
Conditions
Healthy Participants
Interventions
Spinal Stimulation
Device
Lead sponsor
Gail Forrest
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of the Cortex and Spinal Cord

NCT06586437
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Clinical Assessments, Brain-Spinal Cord fMRI, Hoffmann Reflex Assessments, MEG Imaging, Transcutaneous Current Stimulation
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
11 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boys Town, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Understanding Perinatal Spinal Cord Injury

NCT06808035
View directory record Official record
Conditions
Perinatal Spinal Cord Injury
Interventions
Activity-Based Recovery Training, Transcutaneous Spinal Cord Stimulation
Other · Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 8 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Active, not recruiting Not applicable Interventional

Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

NCT05960448
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Transcutaneous Spinal Cord Stimulation (TSCS), Sham Transcutaneous Spinal Cord Stimulation
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Electrical Stimulation for Stroke Patients

NCT06950593
View directory record Official record
Conditions
Upper Limb Hemiparesis Following Stroke
Interventions
Task Specific Training (TST), Transcutaneous electrical spinal cord stimulation (TESS), Sham transcutaneous electrical spinal cord stimulation (Sham TESS)
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Sep 21, 2026, 6:09 PM EDT
Not listed Not applicable Interventional

Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury

NCT05457205
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle
Interventions
Electrical neuromodulation
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 21, 2026, 6:09 PM EDT
Not yet recruiting Not applicable Interventional

Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI

NCT06140706
View directory record Official record
Conditions
Tetraplegia
Interventions
transcutaneous Spinal Cord Stimulation (tSCS)
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 21, 2026, 6:09 PM EDT
Not listed Not applicable Interventional

Trancutaneous Abdominal Stimulation on Bowel Function.

NCT04627168
View directory record Official record
Conditions
Spinal Cord Injuries, Constipation
Interventions
Non-invasive, surface electrical stimulation device, DS5 Digitimer
Device
Lead sponsor
Amol Soin, M.D., MBA
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2022 · Synced Sep 21, 2026, 6:09 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Stimulation-based Therapy to Improve Balance in DCM

NCT07298460
View directory record Official record
Conditions
Degenerative Cervical Myelopathy
Interventions
Transcutaneous spinal cord stimulation, Balance and Gait Training
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 21, 2026, 6:09 PM EDT