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Conditions: Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound, Sexual Function Disturbances, Urinary Incontinence, Urinary Function Disorders, Prostate Biopsy, Ablation
Interventions: TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT); Device
Lead sponsor: Urological Research Network, LLC; Other
Eligibility: 50 Years to 80 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2033
U.S. locations: 1
States / cities: Hialeah, Florida

Conditions: Prostate Cancer
Interventions: Access needle; Procedure
Lead sponsor: Perineologic; Industry
Eligibility: 18 Years to 80 Years · Male only
Enrollment: 230 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Cumberland, Maryland

Conditions: Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam, Prostate Cancer
Interventions: Prostate Biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy; Other · Device
Lead sponsor: Ardeshir Rastinehad; Other
Eligibility: 18 Years and older · Male only
Enrollment: 1,586 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 3
States / cities: Lake Success, New York • New York, New York

Conditions: Prostate Cancer
Interventions: Urinary ExoDx test, Transrectal ultrasound-guided prostate biopsy, Transperineal 12-core prostate biopsy; Device · Diagnostic Test
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Male only
Enrollment: 425 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 6
States / cities: New York, New York

Conditions: Prostate Cancer, Low-risk or Favorable Intermediate Risk Prostate Cancer Who Are on an Active Surveillance Regimen
Interventions: TRANBERG®|Thermal Therapy System; Device
Lead sponsor: Genesis Research LLC; Network
Eligibility: 40 Years to 85 Years · Male only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Prostate Cancer
Interventions: Artemis™ software system; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 40 Years to 85 Years · Male only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Cancer
Interventions: Prostate Biopsy, Focal Brachytherapy , Assessment of QOL; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 21 Years and older · Male only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 3
States / cities: New Hyde Park, New York • New York, New York • Houston, Texas

Conditions: Prostate Cancer
Interventions: ClariCore System; Device
Lead sponsor: Precision Biopsy, Inc.; Industry
Eligibility: Male only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Baltimore, Maryland • New York, New York

Conditions: Chronic Pelvic Pain Syndrome
Interventions: Tone, Tenderness, Contraction, Relaxation, Electromyography, Transperineal, Pressure; Diagnostic Test
Lead sponsor: Loyola University; Other
Eligibility: 21 Years to 80 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Neoplasms Prostate, Cancer of the Prostate
Interventions: Image Fusion (MR/US) Software Registration Guided Laser Ablation of Prostate Cancer; Device
Lead sponsor: Urological Research Network, LLC; Other
Eligibility: 50 Years and older · Male only
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2038
U.S. locations: 1
States / cities: Miami Lakes, Florida

Conditions: Prostate Cancer
Interventions: WST 11 -mediated -VTP; Drug
Lead sponsor: Steba Biotech S.A.; Other
Eligibility: 18 Years and older · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 5
States / cities: Los Angeles, California • Atlanta, Georgia • St Louis, Missouri + 1 more

Conditions: Prostate Cancer, Magnetic Resonance Imaging, Target Lesion, Fusion Biopsy, Clinically Significant Prostate Cancer, Transperineal
Interventions: MRI/ultrasound transperineal prostate biopsy, transrectal ultrasound-guided prostate biopsy; Device
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 75 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Prostate Cancer, Elevated PSA
Interventions: prostate biopsy; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Carcinoma
Interventions: Biospecimen Collection, Microwave Ablation, Multiparametric Magnetic Resonance Imaging, Questionnaire Administration, Radical Prostatectomy; Procedure · Device · Other
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older · Male only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Prostate Cancer
Interventions: OnabotulinumtoxinA (BOTOX®), Normal Saline Placebo; Drug · Other
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 45 Years to 80 Years · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Prostate Cancer
Interventions: 125-Iodine, 103-palladium; Radiation
Lead sponsor: Radiation Therapy Oncology Group; Network
Eligibility: 18 Years to 120 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2022
U.S. locations: 13
States / cities: Phoenix, Arizona • Fresno, California • Aurora, Colorado + 10 more

Conditions: Prostate Cancer, Prostate Adenocarcinoma, Multiparametric MRI, Gleason's Score 6
Interventions: TRUS-guided biopsy, mpMRI with targeted biopsy; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 40 Years and older · Male only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Prostate Cancer
Interventions: SpaceOAR System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 20
States / cities: Phoenix, Arizona • Campbell, California • Sacramento, California + 16 more

Conditions: Prostate Cancer (Diagnosis)
Interventions: Prostate biopsy; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 40 Years to 75 Years · Male only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cervix; Pregnancy
Interventions: Butterfly iQ transperineal ultrasound exam; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Prostate Cancer, Post-Prostatectomy
Interventions: Transperineal Ultrasound; Device
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 18 Years to 100 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Prostate Carcinoma
Interventions: Biopsy of Prostate, Magnetic Resonance Imaging, Micro-ultrasound Imaging; Procedure
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Prostate Cancer
Interventions: Transperineal Ultrasound; Device
Lead sponsor: H. James Wallace, MD; Other
Eligibility: 18 Years and older · Male only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Prostate Cancer
Interventions: Transperineal biopsy Protocol; Procedure
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 120 Years · Male only
Enrollment: 157 participants
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Brooklyn, New York

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TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer

Prostate Biopsy Access Needle & Needle Guide Feasibility Study

MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer

ExosomeDx in MRI-negative Men With High PSA

Investigator Initiated Trial to Further Evaluate the Safety and Efficacy of Trans-perineal Focal Laser Ablation of Localized Prostate Cancer Using High Frequency Micro-ultrasound Imaging

Comparative Analysis of Transperineal Versus Transrectal Approaches for MRI-Targeted Biopsy of the Prostate for the Detection and Characterization of Prostate Cancer

Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Early Stage, Low Volume Prostate Cancer

ClariCore System Used in Transperineal Prostate Biopsy

Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions

MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer

Safety and Tolerability Study Using WST11 In Patients With Localized Prostate Cancer

Detection of Clinically Significant Prostate Cancer Using Transperineal Targeted Biopsy Compared to Standard Transrectal Biopsy

A Prospective, Randomized Trial Comparing Office-based MR-guided Prostate Biopsy Approaches

Prostate Resection After Microwave Ablation (PRAMA)

Neoadjuvant Intraprostatic OnabotulinumtoxinA Before Radical Prostatectomy for High-Risk Localized Prostate Cancer

Ultrasound-Guided Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer Previously Treated With External-Beam Radiation Therapy

MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk Prostate Ca

SpaceOAR System Pivotal Study

Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

Sound Check-Correlation Between Transperineal and Digital Cervical Exam in 3rd Trimester Pregnancy

Evaluation Of Transperineal Ultrasound For Image Guidance In The Treatment Of Prostate Cancer in Men Following Prostatectomy

Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy

The Use of Transperineal Ultrasound for Radiation Therapy Treatment Planning and Image Guidance in the Treatment of Prostate Cancer

Reduction of Prostate Biopsy Morbidity