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Showing 1–24 of 81 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Transversus Abdominis Plane (TAP) block Clear all
Completed Not applicable Interventional Results available

The Effect of Pre-Operative Transversus Abdominis Plane (TAP) Block in the Post Operative Opioid Consumption in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study

NCT01075087
View directory record Official record
Conditions
Pain, Obesity, Surgery
Interventions
Placebo, (study group) will receive a bilateral TAP block using 20 cc of 0.5% ropivacaine on each side.
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Sep 28, 2026, 11:36 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

TAP Blocks vs. IV Lidocaine for Kidney Transplants

NCT03843879
View directory record Official record
Conditions
Postoperative Pain
Interventions
Transversus Abdominis Plane Block, Intravenous Lidocaine
Procedure · Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Sep 28, 2026, 11:36 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia

NCT02893423
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ropivacaine
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Phase 4 Interventional Results available

TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy

NCT02519023
View directory record Official record
Conditions
Acute Pain
Interventions
Liposomal Bupivacaine, Bupivacaine, Ultrasound, Epinephrine, acetaminophen, ibuprofen, Oxycodone
Drug · Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections

NCT03176459
View directory record Official record
Conditions
C-Section, Pain Management
Interventions
Exparel + Bupivacaine, Bupivacaine
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
12
States / cities
Loma Linda, California • Stanford, California • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Sep 28, 2026, 11:36 AM EDT
Terminated Not applicable Interventional Results available

Transversus Abdominis Plane Blocks for Ileostomy Takedown: A Prospective Study

NCT01411917
View directory record Official record
Conditions
Ileostomy - Stoma
Interventions
Transversus abdominis plane block
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 9, 2019 · Synced Sep 28, 2026, 11:36 AM EDT
Recruiting Not applicable Interventional

TAP Block Timing Study

NCT07064200
View directory record Official record
Conditions
Bariatric or General Abdominal Surgeries, Bariatric Surgery Patients
Interventions
TAP Block
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Regional TAP Block for Bariatric Patients

NCT04051684
View directory record Official record
Conditions
Bariatric Surgery, Transverse Abdominal Plane Regional Blocks
Interventions
Transverse abdominal plane block, Ropivacaine
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication

NCT02314104
View directory record Official record
Conditions
Pain, Postoperative
Interventions
ropivacaine
Drug
Lead sponsor
Liberman, Eric, D.O.
Individual
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Sep 28, 2026, 11:36 AM EDT
Completed No phase listed Observational

Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates

NCT01557985
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 28 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Phase 2 Interventional

Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain

NCT01906944
View directory record Official record
Conditions
Abdominal Pain
Interventions
Bupivacaine 0.25%, Triamcinolone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance

NCT03577912
View directory record Official record
Conditions
Post Operative Analgesia, Non-inferiority Trial
Interventions
TAP block administered by Surgery, TAP block administered by Anesthesia
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2018 · Synced Sep 28, 2026, 11:36 AM EDT
Recruiting Phase 4 Interventional

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

NCT07840183
View directory record Official record
Conditions
Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions
Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block
Drug · Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 28, 2026, 11:36 AM EDT
Not listed Phase 2 Interventional

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

NCT03149783
View directory record Official record
Conditions
Pain, Postoperative, Delirium, Anesthesia, Local
Interventions
Ropivacaine HCL, sodium chloride
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Sep 28, 2026, 11:36 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant

NCT03737604
View directory record Official record
Conditions
Transplant;Failure,Kidney, Pain, Postoperative
Interventions
Ropivacaine Continuous Infusion Catheter, Single Dose Liposomal Bupivicaine
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 28, 2026, 11:36 AM EDT
Recruiting Early Phase 1 Interventional

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

NCT06617949
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
Regional Anesthesia, Hydromorphone Patient Controlled Analgelsic, Epidural local anesthetic infusion
Drug · Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 28, 2026, 11:36 AM EDT
Not listed Not applicable Interventional

TAP Catheters Versus Intrathecal Morphine for Cesarean Section

NCT01593280
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Cesarean Section, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP catheter, intrathecal morphine
Device · Drug
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2012 · Synced Sep 28, 2026, 11:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TOTEM: Trial of TAP Block Effective Medications

NCT04382859
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Transversus abdominis plane (TAP) block with liposomal bupivacaine
Procedure
Lead sponsor
Western Michigan University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Sep 28, 2026, 11:36 AM EDT
Recruiting Phase 4 Interventional

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

NCT06925152
View directory record Official record
Conditions
Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
Interventions
Bupivicaine intervention arm, Placebo arm
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Not applicable Interventional

Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair

NCT01740193
View directory record Official record
Conditions
Pain, Inguinal Hernia
Interventions
TAP Block, Ilioinguinal/iliohypogastric blockade
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 10 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 28, 2026, 11:36 AM EDT
Terminated Not applicable Interventional Results available

Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

NCT02164929
View directory record Official record
Conditions
Laparoscopic Colorectal Resection
Interventions
TAP block, Epidural, Paravertebral block, Acetaminophen 1g IV, Dexamethasone 4mg, Midazolam up to 2mg, Propofol 1-2.5 mg/kg, Sevoflurane to keep a bispectral index of between 40-60, Local infiltration with 10 mL of plain ropivacaine 0.25%, Lidocaine, Epinephrine, Hydromorphone
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 28, 2026, 11:36 AM EDT
Completed Phase 4 Interventional Results available

Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section

NCT03853694
View directory record Official record
Conditions
Elective Cesarean Section, Pain Management
Interventions
50 mcg Duramorph+ EXPAREL + multi-modal pain regimen, 150 mcg Duramorph + multi-modal pain regimen, Exparel TAP + multi-modal pain regimen
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
18
States / cities
Stanford, California • Gainesville, Florida • Jacksonville, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2022 · Synced Sep 28, 2026, 11:36 AM EDT
Terminated Phase 4 Interventional Results available

Postoperative Pain Control Following Renal Transplant

NCT05044429
View directory record Official record
Conditions
Kidney Transplant; Complications, Pain, Postoperative
Interventions
Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Sep 28, 2026, 11:36 AM EDT
Withdrawn Not applicable Interventional

Pain Relief Study of Ultrasound Guided Transverse Abdominis Plane(TAP)Block

NCT01217580
View directory record Official record
Conditions
Cesarean Section
Interventions
0.5% ropivacaine, 0.9% sodium chloride
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 28, 2026, 11:36 AM EDT