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Conditions: Post Traumatic Stress Disorder, Technology, Child Abuse
Interventions: TFCBT, eTFCBT; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 8 Years to 16 Years
Enrollment: 713 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Child Abuse, Posttraumatic Stress
Interventions: TF-CBT, TF-CBT+AAT; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 6 Years to 17 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Harrisburg, Pennsylvania

Conditions: Post-Traumatic Stress Disorder
Interventions: Trauma-focused cognitive behavioral therapy (TF-CBT), Treatment as usual (TAU); Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 8 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 8
States / cities: New York, New York

Conditions: Posttraumatic Stress Disorder
Interventions: Trauma-Focused Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Delaware Division of Prevention and Behavioral Health Services; Government
Eligibility: 7 Years to 17 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Post Traumatic Stress Disorder
Interventions: eTF-CBT, TF-CBT; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 8 Years to 15 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stress Disorders, Post-Traumatic
Interventions: Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill, Placebo Oral Tablet; Behavioral · Drug
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 10 Years to 17 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Stress Disorders, Post-Traumatic
Interventions: Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout; Behavioral · Device
Lead sponsor: Stanford University; Other
Eligibility: 7 Years to 18 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Sacramento, California • San Francisco, California

Conditions: Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
Interventions: Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual, Attention Control; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years to 85 Years
Enrollment: 292 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: PTSD, Adolescent, Psychological Trauma
Interventions: TF-CBT, TAU; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 12 Years to 17 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT), Treatment as Usual (TAU); Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 7 Years to 14 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Substance Use Disorders, PTSD
Interventions: RRFT (Risk Reduction through Family Therapy), ENCOMPASS (Integrated Treatment for Adolescents and Young Adults); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 13 Years to 75 Years
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Autism Spectrum Disorder, PTSD and Trauma-related Symptoms, Autism, Trauma and Stressor Related Disorders, Mental Health Services
Interventions: Trauma-Focused Cognitive Behavioral Therapy, modified for autistic youth; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 6 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions: Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT); Behavioral
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 7 Years to 14 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Trauma, Psychological, Trauma and Stressor Related Disorders
Interventions: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Trauma Patients
Interventions: PSC-TF-CBT; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 8 Years to 14 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Psychological Trauma, Mental Health
Interventions: COAST-IS, TF-CBT Learning Collaborative; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: Not listed
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Posttraumatic Stress Disorder
Interventions: Stepped Care TF-CBT, Standard TF-CBT; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 3 Years to 7 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms, Behavioral Problems, Child Overall Daily Functioning, Child and Guardian Relationship
Interventions: Trauma-focused Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 7 Years to 13 Years
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT); Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 7 Years to 14 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Child Abuse, Sexual
Interventions: Trauma focused cognitive behavioral therapy (TF-CBT), Brief abuse-focused treatment, Brief coping skills treatment, Extended abuse-focused treatment, Extended coping skills treatment; Behavioral
Lead sponsor: Rowan University; Other
Eligibility: 4 Years to 11 Years
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Stratford, New Jersey

Conditions: Stress Disorders, Post-Traumatic
Interventions: Trauma-Focused CBT, Child-Centered Therapy; Behavioral
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 8 Years to 14 Years
Enrollment: 229 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2002
U.S. locations: 3
States / cities: Stratford, New Jersey • Pittsburgh, Pennsylvania

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 18 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Post Traumatic Stress, Overall Functioning, Clinician Fidelity, Supervision
Interventions: Supervision Practices of TF-CBT; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 6 Years to 17 Years
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Posttraumatic Stress Disorder
Interventions: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) augmented with Socialization (S); Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 10 Years to 15 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Rochester, New York

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Improving Quality of Care in Child Mental Health Service Settings

Integrating Animal-Assisted Therapy Into Trauma-Focused Cognitive-Behavioral Therapy for Maltreated Youth

Effectiveness of Trauma-Focused Cognitive Behavioral Therapy in Treating Children With Post-Traumatic Stress Disorder

Trauma-Focused Cognitive Behavior Therapy for Youth: Effectiveness in a Community Setting

Technology-Based Tools to Enhance Quality of Care in Mental Health Treatment

Pharmacologic Treatment of PTSD in Sexually Abused Children

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy

Neural Connectivity During Therapy for Adolescent PTSD

Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT)

Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens

TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence

Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)

Using a Primary Care- Based Stepped-Care Model of Trauma Focused Cognitive Behavioral Therapy (PSC-TF-CBT)to Reduce Trauma Symptoms and Negative Mental Health Sequelae

Collaborative Organizational Approach to Selecting and Tailoring Implementation Strategies

Stepped Care for Young Children After Trauma

Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya

Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)

Optimal Treatment Strategies for Sexually Abused Children

Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children

Examining Written Exposure Therapy Delivered to Adolescents

Randomized Controlled Trial of Supervision Strategies to Improve Clinician Fidelity to Trauma-focused CBT

Resilient Roots: Supporting Youth and Families