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Conditions: Fall, Fear of Falling, Physical Inactivity, Sedentary Behavior
Interventions: Physio-feedback, Cognitive reframing, Peer-led exercises, CDC older adults fall prevention; Behavioral
Lead sponsor: University of Central Florida; Other
Eligibility: 60 Years and older
Enrollment: 340 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 18 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
Interventions: Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education, Sleep Education enhanced with Nightmare Education; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Sexual Trauma
Interventions: Men's MST Group, Present-Centered Group Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Male only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: West Los Angeles, California

Conditions: Trauma
Interventions: Neurofeedback Intervention, standard of care; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 6 Years to 12 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Hospital-based Violence Intervention, Community Firearm Violence, Firearm Behaviors
Interventions: Brief Bedside, Peer Support, Case Management + Voucher, SELF Group Therapy Sessions; Behavioral
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: TBI (Traumatic Brain Injury), PTSD
Interventions: V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral; Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
Interventions: Prolonged exposure; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
Interventions: Varenicline, Medication Management Counseling, Prolonged Exposure; Drug · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment, Concussion, Multiple Sclerosis, Neuropathy, Parkinson's, Restless Legs Syndrome, Stroke
Interventions: Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description); Drug
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years to 100 Years
Enrollment: 3,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Evanston, Illinois

Conditions: Complicated Grief, Bereavement
Interventions: Citalopram, Complicated Grief Treatment, Placebo; Drug · Behavioral · Other
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 95 Years
Enrollment: 395 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 4
States / cities: San Diego, California • Boston, Massachusetts • New York, New York + 1 more

Conditions: Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions: Mindfulness Based Relapse Prevention (MBRP); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Individuals Who Use Violence, Interpersonal Violence
Interventions: Program For Alleviating Relationship Trauma and Stress through New Behaviors, DVIT Treatment As Usual (TAU); Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older · Male only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Malden, Massachusetts • Tumwater, Washington

Conditions: Post-Traumatic Stress Disorder
Interventions: Cognitive Processing Therapy (CPT); Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Hines, Illinois • Madison, Wisconsin

Conditions: Chronic Pain
Interventions: Behavior Change Coaching, Nutrition, Autonomic Recalibration, Dry Needling, Osteopathic Manipulative Treatment, Counseling Psychology, Multiple Treatments; Behavioral · Other · Procedure
Lead sponsor: Edward Via Virginia College of Osteopathic Medicine; Other
Eligibility: 21 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder, Fear of Falling
Interventions: Exposure-based Cognitive Behavioral Therapy, Relaxation Training; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 60 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: PTSD, Marital Relationship
Interventions: CBCT for PTSD, Prolonged Exposure; Behavioral
Lead sponsor: Toronto Metropolitan University; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 3
States / cities: Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas

Conditions: Nonsuicidal Self-injury
Interventions: Mindfulness; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 12 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms, Behavioral Problems, Child Overall Daily Functioning, Child and Guardian Relationship
Interventions: Trauma-focused Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 7 Years to 13 Years
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Use Disorder, Early Trauma Complications
Interventions: 8-week outpatient treatment; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Posttraumatic Stress Disorder, Alcohol Use Disorders
Interventions: Brief Cognitive Therapy; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Substance Abuse, Families, Trauma
Interventions: Multidimensional Family Therapy, Group CBT; Other
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 17 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Miami, Florida • Luling, Louisiana

Conditions: Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions: webSTAIR, ExpoTx, PsychoEd; Behavioral · Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Female only
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: PTSD, Cognitive Performance
Interventions: Cognitive Processing Therapy, Eye-Movement Desensitization and Reprocessing; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Fayetteville, North Carolina

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Optimizing a Technology-based Body and Mind Intervention

Adaptation and Randomized Controlled Trial of Written Exposure Therapy for Adolescents

Restorative Early Sleep Treatment After the Emergency Department

Recovery-oriented Group Therapy for Veteran Men With Military Sexual Trauma

A Trial of Neurofeedback as an Adjunctive Treatment for Youth in Outpatient Mental Health Settings

The HVIP+ Community Model

Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

Treatment of Smoking Among Individuals With PTSD

Quality Improvement and Practice Based Research in Neurology Using the EMR

A Study of Medication With or Without Psychotherapy for Complicated Grief

Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD

Program for Alleviating Relationship Trauma and Stress for Intimate Partner Violence - Randomized Control Trial

Comparison of Videoconference and Face-to-Face Delivery of Cognitive Processing Therapy for Posttraumatic Stress Disorder

VCOM Pain Free Research Collaborative

Back on My Feet: Emotional Recovery From Fall Injury

Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder

Interrupting Self-Harm Study

Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya

Neurobiological Responses in Alcoholism and Early Trauma

Brief Restructuring Intervention Following Trauma Exposure

Family-Based Drug Services for Young Disaster Victims

Multifaceted Intervention to Restore Resilience and Overcome Risk

Examining the Efficacy of Short-Term Intensive PTSD Treatment on Psychological and Cognitive Impairment Symptoms