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ClinicalTrials.gov public records Last synced Oct 15, 2026, 2:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 576 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment As Usual/TAU Clear all
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers

A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic

NCT05144685
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
OTX-202, OTX-000, Treatment as Usual
Device · Behavioral
Lead sponsor
Oui Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
356 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
6
States / cities
Denver, Colorado • New Haven, Connecticut • Omaha, Nebraska + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Enhancing Addiction Treatment Through Psychoeducation

NCT07178158
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Installing the Metacognium software app, Continue treatment as usual
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

NCT06513156
View directory record Official record
Conditions
Opioid Use Disorder, Injection Related Infections, Stimulant Use Disorder
Interventions
Integrated Infectious Diseases and Substance Use Disorder Clinic (IC)
Behavioral
Lead sponsor
Elana Rosenthal
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

NCT04269772
View directory record Official record
Conditions
Bipolar Disorder
Interventions
CARE, Treatment As Usual
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Cranston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Childbirth Education Pilot Study

NCT04327557
View directory record Official record
Conditions
Pregnancy, Anxiety
Interventions
MBCP Childbirth Education Course, Non-MBCP Childbirth Education Course
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Improving Health for Older Adults With Pain Through Engagement

NCT06119698
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain
Interventions
GetActive+
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Active, not recruiting Not applicable Interventional

Outpatient VR (Virtual Reality)-Brain-gut Behavioral Therapies (BGBT) in Inflammatory Bowel Disease (IBD)

NCT06910787
View directory record Official record
Conditions
Inflammatory Bowel Diseases
Interventions
VR-directed BGBT, E-TAU
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

A Brief Community Linkage Intervention for Dually Diagnosed Individuals

NCT00137267
View directory record Official record
Conditions
Schizophrenia, Psychotic Disorders, Substance-Related Disorders, Bipolar Disorder
Interventions
Time limited case management, Health Education
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Bedford, Massachusetts • East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 15, 2015 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

NCT05181891
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Nicotine Use Disorder
Interventions
Contingency Management, Non-contingent control
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Sleep-Disordered Breathing and PAP in Perinatal Depression

NCT02507297
View directory record Official record
Conditions
Sleep-disordered Breathing, Major Depressive Disorder
Interventions
Positive Airway Pressure (PAP)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Phase 2Phase 3 Interventional

EXHIT ENTRE Comparative Effectiveness Trial

NCT04345718
View directory record Official record
Conditions
Substance Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
Interventions
Extended Release Buprenorphine, Treatment as Usual
Drug
Lead sponsor
Gavin Bart
Other
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
New Haven, Connecticut • Baltimore, Maryland • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

HIV+ Substance Users Released From Jail

NCT03834779
View directory record Official record
Conditions
HIV/AIDS, Substance Use Disorders
Interventions
DOORS-CHW Intervention
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Project Matter: Intervention to Improve HIV Self-care Among Men Who Have Sex With Men (MSM) With Substance Use Disorders

NCT03899220
View directory record Official record
Conditions
Substance Use Disorders, HIV/AIDS, Homosexuality, Male
Interventions
Project Matter
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

NCT06456762
View directory record Official record
Conditions
Parents, Self Efficacy, Mental Health Literacy, Psychiatric Emergency
Interventions
iPEACE: Intervention for Parent Education about Care after the ED, Text Messaging Reminders Only
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)

NCT01542528
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
IBBS
Behavioral
Lead sponsor
Yale University
Other
Eligibility
5 Years to 10 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
3
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 15, 2026, 2:06 AM EDT
Active, not recruiting Not applicable Interventional

Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study

NCT06193512
View directory record Official record
Conditions
Oral Bacterial Infection, Mechanical Ventilation Complication
Interventions
SwishKit + Oral care treatment as usual, Oral care treatment as usual
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 15, 2026, 2:06 AM EDT
Terminated Not applicable Interventional

Data-driven Approaches to Healthcare Provider Resilience & Burnout During COVID-19

NCT04922632
View directory record Official record
Conditions
Burnout, Professional, Exhaustion, Caregiver, Covid19
Interventions
Transcendental Meditation (TM), Experience Resolution Methodology (ERM), Transcendental Meditation (TM) and Experience Resolution Methodology (ERM), Treatment As Usual (TAU)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 15, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities

NCT06904508
View directory record Official record
Conditions
Autism Spectrum Disorder, Anxiety
Interventions
Facing Your Fears (FYF) Intervention: A CBT Focused Group Treatment for Autistic Youth with Anxiety
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
8 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Montclair, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional

START NOW in the Treatment of Opioid Addicted Individuals

NCT05552040
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
START NOW Group
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2022 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Pelvic Pain Education and Skills Training for Women Veterans

NCT06062043
View directory record Official record
Conditions
Pelvic Pain, Distress, Emotional
Interventions
Brief ACT with CPP Education Treatment
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing

NCT05479890
View directory record Official record
Conditions
Motivational Interviewing, Alcohol Use Disorder
Interventions
ClientBot
Other
Lead sponsor
Lyssn.io, Inc.
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic

NCT04632368
View directory record Official record
Conditions
Burnout, Professional, Stress, Psychological
Interventions
Transcendental Meditation
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Oct 15, 2026, 2:06 AM EDT
Active, not recruiting Not applicable Interventional

Integrated Care and Treatment for Severe Infectious Diseases and Substance Use Disorders Among Hospitalized Patients

NCT05688423
View directory record Official record
Conditions
Injection Site Infection, Substance Use Disorders
Interventions
SIRI Team, Treatment as Usual
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Miami, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 15, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Therapy

NCT05797441
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
EMPOWER, Treatment As Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Sepulveda, California • Tampa, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 15, 2026, 2:06 AM EDT