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ClinicalTrials.gov public records Last synced Oct 13, 2026, 8:50 PM EDT

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Showing 313–336 of 576 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment As Usual (TAU) Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth

NCT03709472
View directory record Official record
Conditions
Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation, Family Relations
Interventions
Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
11 Years to 18 Years
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional

New Technologies for Cognitive Behavior Therapy (CBT) Treatment of Adolescent Depression

NCT01868867
View directory record Official record
Conditions
Depression
Interventions
Intervention
Behavioral
Lead sponsor
Center for Psychological Consultation
Other
Eligibility
13 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure

NCT06433271
View directory record Official record
Conditions
Adjustment Disorders, Mental Disorder
Interventions
Transdiagnostic Behavior Therapy (TBT), Treatment as Usual-Problem Solving Therapy (TAU-PST)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Phase 1 Interventional

MethaLoad Dose-Finding Study

NCT06877858
View directory record Official record
Conditions
Opioid Use Disorder (OUD)
Interventions
Methadone hydrochloride
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

NCT05973838
View directory record Official record
Conditions
Polysubstance Addiction, Opioid Medication Assisted Treatment, Treatment Adherence, Retention in Care, Substance-Related Disorders
Interventions
Peer-Delivered Behavioral Activation ("Peer Activate")
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • College Park, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional

Striving Towards EmPowerment and Medication Adherence (STEP-AD)

NCT02764853
View directory record Official record
Conditions
HIV
Interventions
Experimental Intervention (STEP-AD), Enhanced Treatment as Usual (E-TAU)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Miami, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Phase 1Phase 2 Interventional

Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders

NCT00600470
View directory record Official record
Conditions
Attention Deficit and Disruptive Behavior Disorders
Interventions
Doctor-office collaborative care (DOCC) management, Treatment as usual (TAU)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 12 Years
Enrollment
858 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study

NCT05380583
View directory record Official record
Conditions
Psychosis, Substance Use, Substance Use Disorders, Family, Cannabis, Marijuana, Alcohol, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Mental Disorder
Interventions
CRAFT-EP, TAU
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

NCT03755401
View directory record Official record
Conditions
PTSD
Interventions
TFPP, TAU
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Mindfulness Based Relapse Prevention: Efficacy and Mechanisms

NCT01159535
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Mindfulness Based Relapse Prevention, Relapse Prevention, Treatment as Usual
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease

NCT07210580
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
MBC-IBD Intervention, Enhanced Treatment as Usual (E-TAU)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
Decatur, Georgia • Ann Arbor, Michigan • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Not yet recruiting Not applicable Interventional

Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial

NCT07782268
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
Interventions
Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of Extended Treatments for Drug Dependence

NCT00685659
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Intensive Outpatient Treatment, Adaptive telephone-based counseling, Adaptive telephone-based counseling plus incentives
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

NCT06456762
View directory record Official record
Conditions
Parents, Self Efficacy, Mental Health Literacy, Psychiatric Emergency
Interventions
iPEACE: Intervention for Parent Education about Care after the ED, Text Messaging Reminders Only
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Comparing Treatments for HIV-Infected Opioid Users in an Integrated Care Effectiveness Study (CHOICES) Scale-Up

NCT03275350
View directory record Official record
Conditions
Opioid-use Disorder, Hiv
Interventions
Naltrexone Injectable Suspension, Treatment as usual
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Tarzana, California • Miami, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Phase 3 Interventional

Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment

NCT01457391
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy, Individual Addiction Counseling, Treatment-as-usual
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
4
States / cities
Berlin Corners, Vermont • Brattleboro, Vermont • Burlington, Vermont + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2015 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Results available

Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders

NCT03315208
View directory record Official record
Conditions
Substance Use Disorders, Depression, Anxiety, Emotional Disorder, Suicidal Ideation, Suicidal and Self-injurious Behavior
Interventions
Unified Protocol (UP), Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Results available

Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD

NCT03696225
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Compensatory Cognitive Training (CCT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Phase 3 Interventional

Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

NCT06333990
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Quetiapine Fumarate, TAU
Drug
Lead sponsor
Foundation for Advancing Veterans' Health Research
Other
Eligibility
18 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Albuquerque, New Mexico • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 13, 2026, 8:50 PM EDT
Recruiting Not applicable Interventional

A Toolkit to Improve Mental Health Treatment for Autistic Individuals

NCT07539519
View directory record Official record
Conditions
Autism, Mental Health Conditions
Interventions
Enhanced Psychotherapy, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
13 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Results available

Improving Outcomes for Individuals With Serious Mental Illness and Diabetes

NCT01410357
View directory record Official record
Conditions
Diabetes Mellitus, Bipolar Disorder, Depression, Psychotic Disorders, Schizophrenia
Interventions
Targeted Training in Illness Management (TTIM)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeting Worry to Improve Sleep

NCT03684057
View directory record Official record
Conditions
Anxiety, Sleep Disturbance
Interventions
App-Delivered Mindfulness Training (MT)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Phase 3 Interventional

Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients

NCT04271917
View directory record Official record
Conditions
Pain, Acute
Interventions
cannabidiol, placebo, acetaminophen 500mg and ibuprofen 200mg combo
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 13, 2026, 8:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

NCT02028247
View directory record Official record
Conditions
Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified, Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder
Interventions
Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 13 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 13, 2026, 8:50 PM EDT