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ClinicalTrials.gov public records Last synced Oct 14, 2026, 9:03 AM EDT

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Showing 505–528 of 576 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment As Usual (TAU) Clear all
Completed Not applicable Interventional

Technology Enhanced Behavioral Activation Treatment for Substance Use

NCT02707887
View directory record Official record
Conditions
Substance-Related Disorders, Depressive Disorder, Behavioral Symptoms, Risk-Taking, Sexual Behavior
Interventions
LETS ACT, LETS ACT-SE, Treatment as Usual
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

Intensive Models of HCV Care for Injection Drug Users

NCT01857245
View directory record Official record
Conditions
Hepatitis C, Medication Adherence
Interventions
Intensive Models (mDOT and CGT) of HCV Care
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Phase 2 Interventional Results available

A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression

NCT06229977
View directory record Official record
Conditions
Bipolar Depression
Interventions
Palmitoylethanolamide (PEA), Placebo, Treatment as Usual (TAU)
Drug
Lead sponsor
Rodrigo Machado-Vieira, MD, PhD, MSc
Other
Eligibility
18 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition

NCT06651528
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Michele Staton
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
4
States / cities
Frankfort, Kentucky • Pewee Valley, Kentucky • Chillicothe, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Phase 4 Interventional Results available

Extended Release Naltrexone for Opioid-Dependent Youth

NCT01843023
View directory record Official record
Conditions
Drug Dependence
Interventions
Extended Release Naltrexone, Psychosocial Treatment, Buprenorphine
Drug · Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
15 Years to 21 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 14, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services

NCT06769282
View directory record Official record
Conditions
Aggression Childhood, Teen Dating Violence
Interventions
Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Telehealth to Improve Prevention of Suicide (TIPS)

NCT04800029
View directory record Official record
Conditions
Suicide Risk
Interventions
TIPS Program, TIPS Program + ED-SAFE
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
32,406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of EBT With Young, Substance Abusing Homeless Mothers

NCT02577666
View directory record Official record
Conditions
Substance Use
Interventions
Ecologically Based Therapy, Housing Only, Treatment as Usual
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

TECH App Marijuana Use Intervention for Court-Involved Adolescents

NCT05979272
View directory record Official record
Conditions
Cannabis Use, Adolescent
Interventions
Treatment as usual, Teen Empowerment through Computerized Health (TECH) app
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
14 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Phase 4 Interventional Results available

Primary Care Intervention Strategy for Anxiety Disorders

NCT00347269
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
Interventions
Cognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
Behavioral · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 75 Years
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
4
States / cities
Little Rock, Arkansas • La Jolla, California • Los Angeles, California + 1 more
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

African American Knowledge Optimized for Mindfully Healthy Adolescents

NCT00578318
View directory record Official record
Conditions
Depression
Interventions
Motivational Interviewing Active
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
11 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2013 · Synced Oct 14, 2026, 9:03 AM EDT
Active, not recruiting Not applicable Interventional

Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)

NCT05688410
View directory record Official record
Conditions
Opioid Use Disorder, Pain
Interventions
Exercise, Psychotherapy Pain and Addiction (I-STOP)
Other · Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Denver, Colorado • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

NCT06088303
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE)
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents

NCT01118988
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS), Myofacial Pain, Chronic Daily Headaches, Migraine Headaches, Chronic Pain
Interventions
Mentorship
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 14, 2026, 9:03 AM EDT
Completed No phase listed Observational

The Effects of Home-Based Telemental Health for Rural Veterans With PTSD

NCT02295410
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
CPT
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Automated Recovery Line for Medication Assisted Treatment

NCT02124980
View directory record Official record
Conditions
Drug Dependence, Substance Use Disorders
Interventions
Recovery Line
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 14, 2026, 9:03 AM EDT
Terminated Phase 3 Interventional

Helping Children With Trauma

NCT02737488
View directory record Official record
Conditions
Trauma, Post-Traumatic Stress Disorder
Interventions
Trauma Systems Therapy (TST), Treatment as Usual (TAU)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
7 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple Sclerosis

NCT04147052
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
iSLEEPms
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

Research on Improving Sleep During Pregnancy

NCT05017974
View directory record Official record
Conditions
Sleep, Pregnancy Related
Interventions
Mindfulness-Based Stress Reduction plus Prenatal Sleep supplement, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa

NCT02883413
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
CRT + Teach the Parent, CRT + Contact Control
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of the Vermont Family Based Approach in Primary Care Pediatrics

NCT04412590
View directory record Official record
Conditions
Psychiatric Disorder
Interventions
Vermont Family Based Approach, Treatment as Usual
Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
3 Years to 15 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 14, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

SilverCloud as a School-Based Intervention for Vulnerable Youth

NCT06004414
View directory record Official record
Conditions
Depression, Anxiety
Interventions
App-based Cognitive Behavioral Therapy (CBT), Psychotherapy
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
13 Years to 22 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
New Brunswick, New Jersey • Brooklyn, New York • Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 14, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Clinical Monitoring to Facilitate Continuous Care for Substance Abusing Clients

NCT01831999
View directory record Official record
Conditions
Substance-Related Disorders, Mental Disorders
Interventions
RecoveryTrack - Extended Care (RT-E)
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
Collingswood, New Jersey • Marlton, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 14, 2026, 9:03 AM EDT
Terminated Not applicable Interventional

Evaluating Outcomes for Youth Receiving Hospital-based Violence Prevention With and Without a Community-level Initiative

NCT04192318
View directory record Official record
Conditions
Violence in Adolescence
Interventions
Bridging the Gap, Communities that Care (CTC), Treatment as usual
Behavioral · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 21 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 14, 2026, 9:03 AM EDT