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ClinicalTrials.gov public records Last synced Oct 15, 2026, 7:08 PM EDT

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Showing 433–456 of 3,321 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Treatment as Usual + Clear all
Not listed Not applicable Interventional

De-resuscitation Informed by Ultrasound for Patients With Sepsis

NCT04921319
View directory record Official record
Conditions
Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Interventions
VExUS score
Diagnostic Test
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 15, 2026, 7:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

NCT06501781
View directory record Official record
Conditions
HIV Infections, Substance Use
Interventions
Peer Activate-LAI, Standard of Care HIV treatment or prevention with LAI-PrEP/ART
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Phase 3 Interventional

Telephone-Based Care Management Program for Individuals With Anxiety Disorders

NCT00158327
View directory record Official record
Conditions
Anxiety Disorders, Panic Disorder
Interventions
Telephone-based collaborative care, Usual care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 64 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2014 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19

NCT04547283
View directory record Official record
Conditions
Covid19, Respiratory Failure
Interventions
Usual Care, APPS
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 15, 2026, 7:08 PM EDT
Active, not recruiting Not applicable Interventional

Investigating Metabolic and Psychological Adaptations in a Clinical Trial

NCT06800794
View directory record Official record
Conditions
Obesity and Type 2 Diabetes
Interventions
Behavioral Skill Training, Meal Provisioning
Behavioral · Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 15, 2026, 7:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery

NCT02900794
View directory record Official record
Conditions
Sinusitis
Interventions
Gold Laser, Microdebridement
Device · Procedure
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional

CONtrolling Disease Using Inexpensive IT - Hypertension in Diabetes

NCT01416766
View directory record Official record
Conditions
Hypertension, Diabetes Mellitus
Interventions
Self-monitoring-nurse-primary care provider feedback loop
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 80 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2015 · Synced Oct 15, 2026, 7:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities

NCT04340531
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Best Practice, Survey Administration, Tobacco Cessation Counseling, Training
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 64 Years
Enrollment
810 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
4
States / cities
Lexington, Kentucky • Columbus, Ohio • Charlottesville, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Phase 4 Interventional Results available

Study to Measure the Safety of Paliperidone ER (Extended-release) in Patients With Liver Disease

NCT00535145
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Psychotic Disorders
Interventions
Treatment as usual (TAU), Paliperidone ER
Drug
Lead sponsor
Ortho-McNeil Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
21
States / cities
Cerritos, California • Chino, California • Garden Grove, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Sensory Integration Therapy in Autism: Mechanisms and Effectiveness

NCT02536365
View directory record Official record
Conditions
Autism
Interventions
Sensory Integration Therapy, Applied Behavioral Analysis
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
6 Years to 114 Months
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease

NCT00600665
View directory record Official record
Conditions
Anemia, Sickle Cell, Hemoglobin SC Disease
Interventions
PAINReportIt (Phase 1 + 2), PAINUCope (Phase 1), PAINConsultN (Phase 2), PAINUCope (Phase 2)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy

NCT04992767
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Pregnancy Related
Interventions
Sunnyside, SunnysideFlex
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 15, 2026, 7:08 PM EDT
Terminated Not applicable Interventional Results available

Trial Comparing PLA to HIGRT (PROVE-HCC)

NCT03402607
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
Percutaneous Local Ablation, Hypofractionated Image Guided Radiation Therapy
Procedure · Radiation
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 15, 2026, 7:08 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery

NCT07533370
View directory record Official record
Conditions
Perioperative Care, EEG Power Spectra, Delirium - Postoperative
Interventions
Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
Procedure
Lead sponsor
Harrison Shong-Wen Chow
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 15, 2026, 7:08 PM EDT
Active, not recruiting Phase 3 Interventional

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

NCT04379570
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2 Negative Breast Carcinoma, Hormone Receptor Positive Breast Carcinoma, Invasive Breast Carcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8
Interventions
Educational Intervention, Text Message-based Navigation Intervention, Motivational Interviewing, Best Practice, Questionnaire Administration, Quality-of-Life Assessment
Other · Behavioral
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
1,167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
526
States / cities
Birmingham, Alabama • Fairbanks, Alaska • Gilbert, Arizona + 406 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional

A Geriatric Assessment Intervention for Older Cancer Patients Receiving Chemotherapy

NCT01915056
View directory record Official record
Conditions
Cancer
Interventions
GA-driven Intervention
Other
Lead sponsor
University of Rochester
Other
Eligibility
70 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hypnosis to Improve Sleep In Menopause

NCT02187419
View directory record Official record
Conditions
Sleep
Interventions
Hypnosis
Other
Lead sponsor
Baylor University
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 15, 2026, 7:08 PM EDT
Not yet recruiting Not applicable Interventional

Boosting Exercise Adherence in Knee Osteoarthritis

NCT07219732
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Usual PT Care (UC), BOOST-OA
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 15, 2026, 7:08 PM EDT
Completed No phase listed Observational

Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections

NCT04495699
View directory record Official record
Conditions
Urinary Tract Infections, Kidney Stone
Interventions
None - observational
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 15, 2026, 7:08 PM EDT
Not listed Not applicable Interventional

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

NCT01621711
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Substance, Addiction, Alcohol Abuse
Interventions
Linkage patient activation intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
504 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mayo Clinic Traumatic Brain Injury Model System Center: The CONNECT Trial

NCT02088099
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Complex clinical intervention, Treatment as usual
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 15, 2026, 7:08 PM EDT
Not listed Not applicable Interventional

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

NCT05138198
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions
Mediterranean Diet & Physical Activity, Usual Care
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
40 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Intensive Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)

NCT01120067
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Intensive Treatment, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
West Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 15, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Subchondroplasty® Knee RCT

NCT03112200
View directory record Official record
Conditions
Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis
Interventions
Subchondroplasty with Arthroscopy, Arthroscopy Alone
Procedure
Lead sponsor
Zimmer Biomet
Industry
Eligibility
30 Years to 75 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
12
States / cities
Encinitas, California • Loma Linda, California • Stanford, California + 9 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 15, 2026, 7:08 PM EDT