Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 6, 2026, 9:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–108 of 108 matching trials from the live ClinicalTrials.gov search.
Conditions
Knee Osteoarthritis
Interventions
cRFA
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
35 Years to 99 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Sacramento, California • Rochester, New York
Not yet recruiting Not applicable Interventional

Boosting Exercise Adherence in Knee Osteoarthritis

NCT07219732
Conditions
Osteoarthritis, Knee
Interventions
Usual PT Care (UC), BOOST-OA
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Knee Osteoarthritis
Interventions
DoD/VA CPG Core Set + PT, DoD/VA CPG Core Set
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
3
States / cities
San Antonio, Texas • Tacoma, Washington
Recruiting Not applicable Interventional

taVNS in Veterans With Knee OA (AVAHCS)

NCT07804199
Conditions
Knee Osteoarthritis
Interventions
Methylprednisolone acetate, taVNS
Drug · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Decatur, Georgia
Conditions
Osteoarthritis, Pain
Interventions
Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Celecoxib 100 mg, Celecoxib 100 mg Matching Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
32
States / cities
Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 29 more
Withdrawn Not applicable Interventional

rTMS for Relieving Chronic OA Pain

NCT05097729
Conditions
Chronic Pain, Osteo Arthritis Knee
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

Effectiveness Trial for Evaluating IAHA for PFPS

NCT01811654
Conditions
Patellofemoral Pain Syndrome
Interventions
Intra-Articular Hyaluronic Acid-Euflexxa
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis
Interventions
Bone Marrow Derived MSCs, Adipose-derived MSCs, Umbilical Cord Tissue (UCT) MSCs, Corticosteroid injection
Biological · Drug
Lead sponsor
Emory University
Other
Eligibility
40 Years to 70 Years
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Gulf Breeze, Florida • Atlanta, Georgia • Durham, North Carolina + 2 more
Completed No phase listed Observational Accepts healthy volunteers

An Analysis of Potential Sex Differences in Knee Osteoarthritis

NCT01403207
Conditions
Degenerative Joint Disease, Osteoarthritis
Interventions
musculoskeletal
Other
Lead sponsor
Mary O'Connor
Other
Eligibility
65 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Knee Osteoarthritis
Interventions
Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of NMES Therapy for Pain Relief Associated With Knee Osteoarthritis

NCT04367597
Conditions
Knee Osteoarthritis
Interventions
Home-based Neuromuscular Electrical Stimulation (NMES) therapy
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Tucson, Arizona • Houston, Texas • Katy, Texas + 1 more
Not yet recruiting Phase 1Phase 2 Interventional

NANOVAE to Treat Knee Osteoarthritis (KOA)

NCT06606561
Conditions
Knee Osteoarthritis
Interventions
NANOVAE - Acellular Allogenic Human Amniotic Fluid (hAF), 0.9% Sodium Chloride Injection, USP
Drug
Lead sponsor
Nova Vita Laboratory
Industry
Eligibility
21 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chesterfield, Missouri